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Evan W. Newell
Evan W. Newell
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center
Geverifieerd e-mailadres voor fredhutch.org - Homepage
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Dimensionality reduction for visualizing single-cell data using UMAP
E Becht, L McInnes, J Healy, CA Dutertre, IWH Kwok, LG Ng, F Ginhoux, ...
Nature biotechnology 37 (1), 38-44, 2019
39272019
Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates
Y Simoni, E Becht, M Fehlings, CY Loh, SL Koo, KWW Teng, JPS Yeong, ...
Nature 557 (7706), 575-579, 2018
10912018
Unsupervised high-dimensional analysis aligns dendritic cells across tissues and species
M Guilliams, CA Dutertre, CL Scott, N McGovern, D Sichien, S Chakarov, ...
Immunity 45 (3), 669-684, 2016
8112016
Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes
EW Newell, N Sigal, SC Bendall, GP Nolan, MM Davis
Immunity 36 (1), 142-152, 2012
6412012
Identification of cDC1-and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow
A Schlitzer, V Sivakamasundari, J Chen, HRB Sumatoh, J Schreuder, ...
Nature immunology 16 (7), 718-728, 2015
5662015
TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity
JB Huppa, M Axmann, MA Mörtelmaier, BF Lillemeier, EW Newell, ...
Nature 463 (7283), 963-967, 2010
5522010
Developmental analysis of bone marrow neutrophils reveals populations specialized in expansion, trafficking, and effector functions
M Evrard, IWH Kwok, SZ Chong, KWW Teng, E Becht, J Chen, JL Sieow, ...
Immunity 48 (2), 364-379. e8, 2018
5342018
Human innate lymphoid cell subsets possess tissue-type based heterogeneity in phenotype and frequency
Y Simoni, M Fehlings, HN Kløverpris, N McGovern, SL Koo, CY Loh, ...
Immunity 46 (1), 148-161, 2017
4432017
Mapping the human DC lineage through the integration of high-dimensional techniques
P See, CA Dutertre, J Chen, P Günther, N McGovern, SE Irac, M Gunawan, ...
Science 356 (6342), eaag3009, 2017
4102017
Single-cell analysis of human mononuclear phagocytes reveals subset-defining markers and identifies circulating inflammatory dendritic cells
CA Dutertre, E Becht, SE Irac, A Khalilnezhad, V Narang, S Khalilnezhad, ...
Immunity 51 (3), 573-589. e8, 2019
4052019
A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory
L Swadling, S Capone, RD Antrobus, A Brown, R Richardson, EW Newell, ...
Science translational medicine 6 (261), 261ra153-261ra153, 2014
3882014
High-dimensional analysis of the murine myeloid cell system
B Becher, A Schlitzer, J Chen, F Mair, HR Sumatoh, KWW Teng, D Low, ...
Nature immunology 15 (12), 1181-1189, 2014
3812014
High-dimensional analysis delineates myeloid and lymphoid compartment remodeling during successful immune-checkpoint cancer therapy
MM Gubin, E Esaulova, JP Ward, ON Malkova, D Runci, P Wong, ...
Cell 175 (4), 1014-1030. e19, 2018
3602018
Cytofkit: a bioconductor package for an integrated mass cytometry data analysis pipeline
H Chen, MC Lau, MT Wong, EW Newell, M Poidinger, J Chen
PLoS computational biology 12 (9), e1005112, 2016
3402016
Clonal deletion prunes but does not eliminate self-specific αβ CD8+ T lymphocytes
W Yu, N Jiang, PJR Ebert, BA Kidd, S Müller, PJ Lund, J Juang, K Adachi, ...
Immunity 42 (5), 929-941, 2015
3302015
Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire
M Lepore, A Kalinichenko, A Colone, B Paleja, A Singhal, A Tschumi, ...
Nature communications 5 (1), 3866, 2014
3292014
Induced-pluripotent-stem-cell-derived primitive macrophages provide a platform for modeling tissue-resident macrophage differentiation and function
K Takata, T Kozaki, CZW Lee, MS Thion, M Otsuka, S Lim, KH Utami, ...
Immunity 47 (1), 183-198. e6, 2017
3112017
CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages
JR Fergusson, KE Smith, VM Fleming, N Rajoriya, EW Newell, ...
Cell reports 9 (3), 1075-1088, 2014
2982014
Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization
EW Newell, N Sigal, N Nair, BA Kidd, HB Greenberg, MM Davis
Nature biotechnology 31 (7), 623-629, 2013
2972013
Epigenomic-guided mass cytometry profiling reveals disease-specific features of exhausted CD8 T cells
B Bengsch, T Ohtani, O Khan, M Setty, S Manne, S O’Brien, PF Gherardini, ...
Immunity 48 (5), 1029-1045. e5, 2018
2802018
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