Bas Heijmans
Bas Heijmans
Leiden University Medical Center, The Netherlands
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Geciteerd door
Persistent epigenetic differences associated with prenatal exposure to famine in humans
BT Heijmans, EW Tobi, AD Stein, H Putter, GJ Blauw, ES Susser, ...
Proceedings of the National Academy of Sciences 105 (44), 17046-17049, 2008
DNA methylation differences after exposure to prenatal famine are common and timing-and sex-specific
EW Tobi, LH Lumey, RP Talens, D Kremer, H Putter, AD Stein, ...
Human molecular genetics 18 (21), 4046-4053, 2009
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
Nature genetics 53 (9), 1300-1310, 2021
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
S Wahl, A Drong, B Lehne, M Loh, WR Scott, S Kunze, PC Tsai, JS Ried, ...
Nature 541 (7635), 81-86, 2017
DNA methylation aging clocks: challenges and recommendations
CG Bell, R Lowe, PD Adams, AA Baccarelli, S Beck, JT Bell, ...
Genome biology 20, 1-24, 2019
DNA methylation signatures link prenatal famine exposure to growth and metabolism
EW Tobi, JJ Goeman, R Monajemi, H Gu, H Putter, Y Zhang, RC Slieker, ...
Nature communications 5 (1), 5592, 2014
Periconceptional maternal folic acid use of 400 µg per day is related to increased methylation of the IGF2 gene in the very young child
RP Steegers-Theunissen, SA Obermann-Borst, D Kremer, J Lindemans, ...
PloS one 4 (11), e7845, 2009
Disease variants alter transcription factor levels and methylation of their binding sites
MJ Bonder, R Luijk, D Zhernakova, M Moed, P Deelen, M Vermaat, ...
Nature genetics 49 (1), 131–138, 2017
Identification of context-dependent expression quantitative trait loci in whole blood
DV Zhernakova, P Deelen, M Vermaat, M Van Iterson, M Van Galen, ...
Nature genetics 49 (1), 139-145, 2017
From promises to practical strategies in epigenetic epidemiology
J Mill, BT Heijmans
Nature Reviews Genetics 14 (8), 585-594, 2013
Epigenetic variation during the adult lifespan: cross‐sectional and longitudinal data on monozygotic twin pairs
RP Talens, K Christensen, H Putter, G Willemsen, L Christiansen, ...
Aging cell 11 (4), 694-703, 2012
Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology
RP Talens, DI Boomsma, EW Tobi, D Kremer, JW Jukema, G Willemsen, ...
The FASEB Journal 24 (9), 3135-3144, 2010
Reduced insulin/IGF‐1 signalling and human longevity
D Van Heemst, M Beekman, SP Mooijaart, BT Heijmans, BW Brandt, ...
Aging cell 4 (2), 79-85, 2005
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
N Kato, M Loh, F Takeuchi, N Verweij, X Wang, W Zhang, TN Kelly, ...
Nature genetics 47 (11), 1282-1293, 2015
Genetic and environmental influences interact with age and sex in shaping the human methylome
J Van Dongen, MG Nivard, G Willemsen, JJ Hottenga, Q Helmer, ...
Nature communications 7 (1), 11115, 2016
Genome‐wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited
J Deelen, M Beekman, HW Uh, Q Helmer, M Kuningas, L Christiansen, ...
Aging cell 10 (4), 686-698, 2011
Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study
RGJ Westendorp, D Van Heemst, MP Rozing, M Frölich, SP Mooijaart, ...
Journal of the American Geriatrics Society 57 (9), 1634-1637, 2009
The epigenome: archive of the prenatal environment
BT Heijmans, EW Tobi, LH Lumey, PE Slagboom
Epigenetics 4 (8), 526-531, 2009
Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single‐nucleotide polymorphisms in genes coding for folate pathway enzymes
JAM Wessels, JK de Vries‐Bouwstra, BT Heijmans, PE Slagboom, ...
Arthritis & Rheumatism 54 (4), 1087-1095, 2006
Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus
BT Heijmans, D Kremer, EW Tobi, DI Boomsma, PE Slagboom
Human molecular genetics 16 (5), 547-554, 2007
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Artikelen 1–20