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Laurent Meijer
Laurent Meijer
Unknown affiliation
Verified email at manros-therapeutics.com
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Year
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
N Sato, L Meijer, L Skaltsounis, P Greengard, AH Brivanlou
Nature medicine 10 (1), 55-63, 2004
26302004
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin‐dependent kinases cdc2, cdk2 and cdk5
L Meijer, A Borgne, O Mulner, JPJ Chong, JJ Blow, N Inagaki, M Inagaki, ...
European journal of biochemistry 243 (1‐2), 527-536, 1997
16121997
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors
NS Gray, L Wodicka, AMWH Thunnissen, TC Norman, S Kwon, ...
Science 281 (5376), 533-538, 1998
11421998
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases
R Hoessel, S Leclerc, JA Endicott, MEM Nobel, A Lawrie, P Tunnah, ...
Nature cell biology 1 (1), 60-67, 1999
10331999
GSK-3-selective inhibitors derived from Tyrian purple indirubins
L Meijer, AL Skaltsounis, P Magiatis, P Polychronopoulos, M Knockaert, ...
Chemistry & biology 10 (12), 1255-1266, 2003
9572003
Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease: A PROPERTY COMMON TO MOST …
S Leclerc, M Garnier, R Hoessel, D Marko, JA Bibb, GL Snyder, ...
Journal of Biological Chemistry 276 (1), 251-260, 2001
9222001
Inhibition of cyclin‐dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine
WF De Azevedo, S Leclerc, L Meijer, L Havlicek, M Strnad, SH Kim
European journal of biochemistry 243 (1‐2), 518-526, 1997
8851997
Inhibition of cyclin‐dependent kinases by purine analogues
J Veselư, L Havliček, M Strnad, JJ Blow, A Donella‐Deana, L Pinna, ...
European journal of biochemistry 224 (2), 771-786, 1994
7961994
Pharmacological inhibitors of glycogen synthase kinase 3
L Meijer, M Flajolet, P Greengard
Trends in pharmacological sciences 25 (9), 471-480, 2004
7472004
Pharmacological inhibitors of cyclin-dependent kinases
M Knockaert, P Greengard, L Meijer
Trends in pharmacological sciences 23 (9), 417-425, 2002
7282002
Constitutive phosphorylation of the Parkinson's disease associated α-synuclein
M Okochi, J Walter, A Koyama, S Nakajo, M Baba, T Iwatsubo, L Meijer, ...
Journal of Biological Chemistry 275 (1), 390-397, 2000
7092000
cdc2 is a component of the M phase-specific histone H1 kinase: evidence for identity with MPF
D Arion, L Meijer, L Brizuela, D Beach
Cell 55 (2), 371-378, 1988
6951988
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
JA Bibb, GL Snyder, A Nishi, Z Yan, L Meijer, AA Fienberg, LH Tsai, ...
Nature 402 (6762), 669-671, 1999
6671999
Inhibition of cyclin-dependent kinases, GSK-3β and CK1 by hymenialdisine, a marine sponge constituent
L Meijer, AMWH Thunnissen, AW White, M Garnier, M Nikolic, LH Tsai, ...
Chemistry & biology 7 (1), 51-63, 2000
5852000
Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25
M Leost, C Schultz, A Link, YZ Wu, J Biernat, EM Mandelkow, JA Bibb, ...
European journal of biochemistry 267 (19), 5983-5994, 2000
4942000
Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases
P Polychronopoulos, P Magiatis, AL Skaltsounis, V Myrianthopoulos, ...
Journal of medicinal chemistry 47 (4), 935-946, 2004
4882004
Roscovitine and other purines as kinase inhibitors. From starfish oocytes to clinical trials
L Meijer, E Raymond
Accounts of chemical research 36 (6), 417-425, 2003
4742003
Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff’s bases
SM Sondhi, N Singh, A Kumar, O Lozach, L Meijer
Bioorganic & medicinal chemistry 14 (11), 3758-3765, 2006
4692006
Roscovitine Targets, Protein Kinases and Pyridoxal Kinase*[Boxs]
S Bach, M Knockaert, J Reinhardt, O Lozach, S Schmitt, B Baratte, ...
Journal of Biological Chemistry 280 (35), 31208-31219, 2005
4272005
Paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity
C Schultz, A Link, M Leost, DW Zaharevitz, R Gussio, EA Sausville, ...
Journal of medicinal chemistry 42 (15), 2909-2919, 1999
4061999
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