Modeling of TREX1-dependent autoimmune disease using human stem cells highlights L1 accumulation as a source of neuroinflammation CA Thomas, L Tejwani, CA Trujillo, PD Negraes, RH Herai, P Mesci, ...
Cell stem cell 21 (3), 319-331. e8, 2017
286 2017 Exosomes regulate neurogenesis and circuit assembly P Sharma, P Mesci, C Carromeu, DR McClatchy, L Schiapparelli, ...
Proceedings of the National Academy of Sciences 116 (32), 16086-16094, 2019
218 2019 Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions M Tang, Q Xie, RC Gimple, Z Zhong, T Tam, J Tian, RL Kidwell, Q Wu, ...
Cell research 30 (10), 833-853, 2020
189 2020 Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxis SA Shiryaev, P Mesci, A Pinto, I Fernandes, N Sheets, S Shresta, C Farhy, ...
Scientific reports 7 (1), 15771, 2017
138 2017 Zika virus targets glioblastoma stem cells through a SOX2-integrin αvβ5 axis Z Zhu, P Mesci, JA Bernatchez, RC Gimple, X Wang, ST Schafer, ...
Cell stem cell 26 (2), 187-204. e10, 2020
137 2020 Altered neuronal network and rescue in a human MECP2 duplication model S Nageshappa, C Carromeu, CA Trujillo, P Mesci, I Espuny-Camacho, ...
Molecular psychiatry 21 (2), 178-188, 2016
116 2016 System is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice P Mesci, S Zaïdi, CS Lobsiger, S Millecamps, C Escartin, D Seilhean, ...
Brain 138 (1), 53-68, 2015
109 2015 Blocking Zika virus vertical transmission P Mesci, A Macia, SM Moore, SA Shiryaev, A Pinto, CT Huang, L Tejwani, ...
Scientific reports 8 (1), 1218, 2018
77 2018 Blocking Zika virus vertical transmission P Mesci, A Macia, SM Moore, SA Shiryaev, A Pinto, CT Huang, L Tejwani, ...
Scientific reports 8 (1), 1218, 2018
77 2018 Motor neuron–immune interactions: the vicious circle of ALS AG Barbeito, P Mesci, S Boillée
Journal of neural transmission 117, 981-1000, 2010
67 2010 Sofosbuvir protects human brain organoids against SARS-CoV-2 P Mesci, A Macia, A Saleh, L Martin-Sancho, X Yin, C Snethlage, ...
BioRxiv, 2020.05. 30.125856, 2020
64 2020 Modeling neuro-immune interactions during Zika virus infection P Mesci, A Macia, CN LaRock, L Tejwani, IR Fernandes, NA Suarez, ...
Human molecular genetics, 2017
56 2017 SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir P Mesci, JS de Souza, L Martin-Sancho, A Macia, A Saleh, X Yin, ...
PLoS biology 20 (11), e3001845, 2022
25 2022 Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury Y Shiga, A Shiga, P Mesci, HJ Kwon, C Brifault, JH Kim, JJ Jeziorski, ...
Scientific reports 9 (1), 19291, 2019
9 2019 Activity of retrotransposons in stem cells and differentiated cells A Macia, L Tejwani, P Mesci, A Muotri, JL Garcia-Perez
Human Retrotransposons in Health and Disease, 127-156, 2017
5 2017 Author correction: Blocking Zika virus vertical transmission P Mesci, A Macia, SM Moore, SA Shiryaev, A Pinto, CT Huang, L Tejwani, ...
Scientific reports 8, 2018
3 2018 Exosomes regulate Neurogenesis and Circuit Assembly in a Model of Rett Syndrome P Sharma, P Mesci, C Carromeu, D McClatchy, L Schiapparelli, ...
bioRxiv, 168955, 2017
1 2017 In-Space Fabrication of Janus Base Nano-Matrix for Improved Assembly and Bioactivities A Yau, M Landolina, MA Snow, P Mesci, B Williams, JB Hoying, D Duflo, ...
bioRxiv, 2024.03. 11.584527, 2024
2024 TREX1 is required for microglial cholesterol homeostasis and oligodendrocyte terminal differentiation in human neural assembloids G Goldberg, L Coelho, G Mo, LA Adang, M Patne, Z Chen, ...
Molecular Psychiatry, 1-14, 2023
2023 Functional cortical organoids, methods of making, and uses thereof AR Muotri, PD Negraes, C Trujillo, P Mesci
US Patent 11,821,895, 2023
2023