Sebo Withoff
Sebo Withoff
Dept. of Genetics, University Medical Center Groningen, the Netherlands.
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Systematic identification of trans eQTLs as putative drivers of known disease associations
HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ...
Nature genetics 45 (10), 1238-1243, 2013
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
MA Sanjuan, CP Dillon, SWG Tait, S Moshiach, F Dorsey, S Connell, ...
Nature 450 (7173), 1253-1257, 2007
Inflammation-associated cancer: NF-κB is the lynchpin
Q Li, S Withoff, IM Verma
Trends in immunology 26 (6), 318-325, 2005
Human disease-associated genetic variation impacts large intergenic non-coding RNA expression
V Kumar, HJ Westra, J Karjalainen, DV Zhernakova, T Esko, B Hrdlickova, ...
PLoS genetics 9 (1), e1003201, 2013
Genetic variation in the non-coding genome: Involvement of micro-RNAs and long non-coding RNAs in disease
B Hrdlickova, RC de Almeida, Z Borek, S Withoff
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (10 …, 2014
A functional genomics approach to understand variation in cytokine production in humans
Y Li, M Oosting, SP Smeekens, M Jaeger, R Aguirre-Gamboa, KTT Le, ...
Cell 167 (4), 1099-1110. e14, 2016
From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases
V Kumar, C Wijmenga, S Withoff
Seminars in Immunopathology, 1-14, 2012
Clinical implications of shared genetics and pathogenesis in autoimmune diseases
A Zhernakova, S Withoff, C Wijmenga
Nature Reviews Endocrinology 9 (11), 646-659, 2013
Differential effects of environmental and genetic factors on T and B cell immune traits
R Aguirre-Gamboa, I Joosten, PCM Urbano, RG van der Molen, ...
Cell reports 17 (9), 2474-2487, 2016
NF-κB and the regulation of hematopoiesis
V Bottero, S Withoff, IM Verma
Cell Death & Differentiation 13 (5), 785-797, 2006
Fas receptor clustering and involvement of the death receptor pathway in rituximab-mediated apoptosis with concomitant sensitization of lymphoma B cells to fas-induced apoptosis
AJ Stel, B Ten Cate, S Jacobs, JW Kok, DCJ Spierings, M Dondorff, ...
The Journal of Immunology 178 (4), 2287-2295, 2007
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity
B Hrdlickova, V Kumar, K Kanduri, DV Zhernakova, S Tripathi, ...
Genome medicine 6 (10), 1-14, 2014
Selection of a subpopulation with fewer DNA topoisomerase II alpha gene copies in a doxorubicin-resistant cell line panel
S Withoff, WN Keith, AJ Knol, JC Coutts, SF Hoare, NH Mulder, ...
British journal of cancer 74 (4), 502-507, 1996
Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia
V Kumar, SC Cheng, MD Johnson, SP Smeekens, A Wojtowicz, ...
Nature communications 5 (1), 1-8, 2014
Isolation and characterization of comL, a transcription unit involved in competence development of Bacillus subtilis
D van Sinderen, S Withoff, H Boels, G Venema
Molecular and General Genetics MGG 224 (3), 396-404, 1990
Resistance‐associated factors in human small‐cell lung‐carcinoma GLC4 sub‐lines with increasing adriamycin resistance
CHM Versantvoort, S Withoff, HJ Broxterman, CM Kuiper, RJ Scheper, ...
International journal of cancer 61 (3), 375-380, 1995
Understanding celiac disease by genomics
S Withoff, Y Li, I Jonkers, C Wijmenga
Trends in Genetics 32 (5), 295-308, 2016
Bi-specific antibody therapy for the treatment of cancer.
S Withoff, W Helfrich, LF De Leij, G Molema
Current opinion in molecular therapeutics 3 (1), 53-62, 2001
A liver‐specific long noncoding RNA with a role in cell viability is elevated in human nonalcoholic steatohepatitis
B Atanasovska, SS Rensen, MR van der Sijde, G Marsman, V Kumar, ...
Hepatology 66 (3), 794-808, 2017
Human DNA topoisomerase II: biochemistry and role in chemotherapy resistance
S Withoff, S De Jong, EG De Vries, NH Mulder
Anticancer research 16 (4A), 1867-1880, 1996
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