Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions F De Sousa E Melo, X Wang, M Jansen, E Fessler, A Trinh, ... Nature medicine 19 (5), 614-618, 2013 | 864 | 2013 |
Immune escape in breast cancer during in situ to invasive carcinoma transition CRG Del Alcazar, SJ Huh, MB Ekram, A Trinh, LL Liu, F Beca, X Zi, ... Cancer discovery 7 (10), 1098-1115, 2017 | 216 | 2017 |
Practical and robust identification of molecular subtypes in colorectal cancer by immunohistochemistry A Trinh, K Trumpi, F De Sousa E Melo, X Wang, JH De Jong, E Fessler, ... Clinical cancer research 23 (2), 387-398, 2017 | 166 | 2017 |
Phylogenetic quantification of intra-tumour heterogeneity RF Schwarz, A Trinh, B Sipos, JD Brenton, N Goldman, F Markowetz PLoS computational biology 10 (4), e1003535, 2014 | 164 | 2014 |
Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes A Marusyk, DP Tabassum, M Janiszewska, AE Place, A Trinh, AI Rozhok, ... Cancer research 76 (22), 6495-6506, 2016 | 126 | 2016 |
Intratumor heterogeneity defines treatment‐resistant HER 2+ breast tumors IH Rye, A Trinh, AB Sætersdal, D Nebdal, OC Lingjærde, V Almendro, ... Molecular oncology 12 (11), 1838-1855, 2018 | 112 | 2018 |
Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier FC Martins, I Santiago, A Trinh, J Xian, A Guo, K Sayal, M Jimenez-Linan, ... Genome biology 15, 1-15, 2014 | 110 | 2014 |
Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data A Trinh, C Lädrach, HE Dawson, S Ten Hoorn, PJK Kuppen, MS Reimers, ... British journal of cancer 119 (10), 1244-1251, 2018 | 79 | 2018 |
EN1 is a transcriptional dependency in triple-negative breast cancer associated with brain metastasis G Peluffo, A Subedee, NW Harper, N Kingston, B Jovanović, F Flores, ... Cancer research 79 (16), 4173-4183, 2019 | 54 | 2019 |
Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer JY Ge, S Shu, M Kwon, B Jovanović, K Murphy, A Gulvady, A Fassl, ... Nature Communications 11 (1), 2350, 2020 | 52 | 2020 |
TRPS1 is a lineage-specific transcriptional dependency in breast cancer RM Witwicki, MB Ekram, X Qiu, M Janiszewska, S Shu, M Kwon, A Trinh, ... Cell reports 25 (5), 1255-1267. e5, 2018 | 48 | 2018 |
Classification of colorectal cancer in molecular subtypes by immunohistochemistry S Ten Hoorn, A Trinh, J de Jong, L Koens, L Vermeulen Colorectal Cancer: Methods and Protocols, 179-191, 2018 | 47 | 2018 |
Neoadjuvant chemotherapy affects molecular classification of colorectal tumors K Trumpi, I Ubink, A Trinh, M Djafarihamedani, JM Jongen, KM Govaert, ... Oncogenesis 6 (7), e357-e357, 2017 | 45 | 2017 |
The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer M Janiszewska, S Stein, O Metzger Filho, J Eng, NL Kingston, NW Harper, ... JCI insight 6 (11), 2021 | 35 | 2021 |
Genomic alterations during the in situ to invasive ductal breast carcinoma transition shaped by the immune system A Trinh, CRG Del Alcazar, SA Shukla, K Chin, YH Chang, G Thibault, ... Molecular Cancer Research 19 (4), 623-635, 2021 | 32 | 2021 |
JAK–STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States LE Stevens, G Peluffo, X Qiu, D Temko, A Fassl, Z Li, A Trinh, ... Cancer Research 83 (2), 264-284, 2023 | 27 | 2023 |
Associations of non-pedunculated T1 colorectal adenocarcinoma outcome with consensus molecular subtypes, immunoscore, and microsatellite status: a multicenter case-cohort study KJC Haasnoot, Y Backes, LMG Moons, O Kranenburg, A Trinh, ... Modern Pathology 33 (12), 2626-2636, 2020 | 26 | 2020 |
Tumor neoantigens: when too much of a good thing is bad A Trinh, K Polyak Cancer cell 36 (5), 466-467, 2019 | 16 | 2019 |
Increased levels of oxidative damage in liver metastases compared with corresponding primary colorectal tumors: association with molecular subtype and prior treatment LM van der Waals, JMJ Jongen, SG Elias, K Veremiyenko, K Trumpi, ... The American journal of pathology 188 (10), 2369-2377, 2018 | 16 | 2018 |
Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone S Ten Hoorn, DW Sommeijer, F Elliott, D Fisher, TR de Back, A Trinh, ... British journal of cancer 125 (8), 1080-1088, 2021 | 15 | 2021 |