Rebecca B. Riggins
Rebecca B. Riggins
Associate Professor of Oncology, Georgetown University
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Pathways to tamoxifen resistance
RB Riggins, RS Schrecengost, MS Guerrero, AH Bouton
Cancer letters 256 (1), 1-24, 2007
Functions of the adapter protein Cas: signal convergence and the determination of cellular responses
AH Bouton, RB Riggins, PJ Bruce-Staskal
Oncogene 20 (44), 6448-6458, 2001
Human X‐box binding protein‐1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines
BP Gomez, RB Riggins, AN Shajahan, U Klimach, A Wang, AC Crawford, ...
The FASEB Journal 21 (14), 4013-4027, 2007
The nuclear factor κB inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)–induced apoptosis in antiestrogen-resistant breast cancer cells
RB Riggins, A Zwart, R Nehra, R Clarke
Molecular cancer therapeutics 4 (1), 33-41, 2005
Interferon regulatory factor-1 (IRF-1) exhibits tumor suppressor activities in breast cancer associated with caspase activation and induction of apoptosis
KB Bouker, TC Skaar, RB Riggins, DS Harburger, DR Fernandez, A Zwart, ...
Carcinogenesis 26 (9), 1527-1535, 2005
Differential dependency network analysis to identify condition-specific topological changes in biological networks
B Zhang, H Li, RB Riggins, M Zhan, J Xuan, Z Zhang, EP Hoffman, ...
Bioinformatics 25 (4), 526-532, 2009
ERRγ mediates tamoxifen resistance in novel models of invasive lobular breast cancer
RB Riggins, JPJ Lan, U Klimach, A Zwart, LR Cavalli, BR Haddad, L Chen, ...
Cancer research 68 (21), 8908-8917, 2008
Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and …
RB Riggins, KS Thomas, HQ Ta, J Wen, RJ Davis, NR Schuh, ...
Cancer research 66 (14), 7007-7015, 2006
Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer
RB Riggins, AH Bouton, MC Liu, R Clarke
Vitamins & Hormones 71, 201-237, 2005
BCL2 and CASP8 regulation by NF‐κB differentially affect mitochondrial function and cell fate in antiestrogen‐sensitive and‐resistant breast cancer cells
R Nehra, RB Riggins, AN Shajahan, A Zwart, AC Crawford, R Clarke
The FASEB Journal 24 (6), 2040-2055, 2010
Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3
RB Riggins, LA Quilliam, AH Bouton
Journal of Biological Chemistry 278 (30), 28264-28273, 2003
IFNγ restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-κB, BCL2 family members, and signaling to caspase-dependent apoptosis
Y Ning, RB Riggins, JE Mulla, H Chung, A Zwart, R Clarke
Molecular cancer therapeutics 9 (5), 1274-1285, 2010
Identifying cancer biomarkers by network-constrained support vector machines
L Chen, J Xuan, RB Riggins, R Clarke, Y Wang
BMC systems biology 5 (1), 1-20, 2011
Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells
R Clarke, AN Shajahan, RB Riggins, Y Cho, A Crawford, J Xuan, Y Wang, ...
The Journal of steroid biochemistry and molecular biology 114 (1-2), 8-20, 2009
Co-inhibition of BCL-W and BCL2 restores antiestrogen sensitivity through BECN1 and promotes an autophagy-associated necrosis
AC Crawford, RB Riggins, AN Shajahan, A Zwart, R Clarke
PloS one 5 (1), e8604, 2010
The role of XBP-1 in tumorigenicity
AN Shajahan, RB Riggins, R Clarke
Drug news & perspectives 22 (5), 241, 2009
Interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (Faslodex, Fulvestrant)
KB Bouker, TC Skaar, DR Fernandez, KA O’Brien, RB Riggins, D Cao, ...
Cancer research 64 (11), 4030-4039, 2004
NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancer
R Hu, A Warri, L Jin, A Zwart, RB Riggins, HB Fang, R Clarke
Molecular and cellular biology 35 (2), 379-390, 2015
Breast cancer antiestrogen resistance-3 expression regulates breast cancer cell migration through promotion of p130Cas membrane localization and membrane ruffling
RS Schrecengost, RB Riggins, KS Thomas, MS Guerrero, AH Bouton
Cancer research 67 (13), 6174-6182, 2007
G-DOC: a systems medicine platform for personalized oncology
S Madhavan, Y Gusev, M Harris, DM Tanenbaum, R Gauba, ...
Neoplasia 13 (9), 771-783, 2011
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