Mike Sutcliffe
Mike Sutcliffe
Deputy Dean, TEDI-London
Geverifieerd e-mailadres voor tedi-london.ac.uk
Geciteerd door
Geciteerd door
Knowledge based modelling of homologous proteins, Part I: Three-dimensional frameworks derived from the simultaneous superposition of multiple structures
MJ Sutcliffe, I Haneef, D Carney, TL Blundell
Protein Engineering, Design and Selection 1 (5), 377-384, 1987
An automated approach for clustering an ensemble of NMR-derived protein structures into conformationally related subfamilies
LA Kelley, SP Gardner, MJ Sutcliffe
Protein Engineering, Design and Selection 9 (11), 1063-1065, 1996
Crystal structure of a PDZ domain
JHM Cabral, C Petosa, MJ Sutcliffe, S Raza, O Byron, F Poy, SM Marfatia, ...
Nature 382 (6592), 649-652, 1996
Atomic description of an enzyme reaction dominated by proton tunneling
L Masgrau, A Roujeinikova, LO Johannissen, P Hothi, J Basran, ...
Science 312 (5771), 237-241, 2006
Knowledge‐based protein modelling and design
T Blundell, D Carney, S Gardner, F Hayes, B Howlin, T Hubbard, ...
European Journal of Biochemistry 172 (3), 513-520, 1988
Knowledge based modelling of homologous proteins, Part II: Rules for the conformations of substituted sidechains
MJ Sutcliffe, FRF Hayes, TL Blundell
Protein Engineering, Design and Selection 1 (5), 385-392, 1987
Enzymatic H-transfer requires vibration-driven extreme tunneling
J Basran, MJ Sutcliffe, NS Scrutton
Biochemistry 38 (10), 3218-3222, 1999
A single aspartate residue is involved in both intrinsic gating and blockage by Mg2+ of the inward rectifier, IRK1.
PR Stanfield, NW Davies, PA Shelton, MJ Sutcliffe, IA Khan, WJ Brammar, ...
The Journal of physiology 478 (1), 1-6, 1994
Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: sequential metabolism of deltamethrin revealed
BJ Stevenson, J Bibby, P Pignatelli, S Muangnoicharoen, PM O’Neill, ...
Insect biochemistry and molecular biology 41 (7), 492-502, 2011
Ligand binding to integrin αIIbβ3 is dependent on a MIDAS-like domain in the β3 subunit
EC Tozer, RC Liddington, MJ Sutcliffe, AH Smeeton, JC Loftus
Journal of Biological Chemistry 271 (36), 21978-21984, 1996
A model for human cytochrome P450 2D6 based on homology modeling and NMR studies of substrate binding
S Modi, MJ Paine, MJ Sutcliffe, LY Lian, WU Primrose, CR Wolf, ...
Biochemistry 35 (14), 4540-4550, 1996
A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation
CF Oliver, S Modi, MJ Sutcliffe, WU Primrose, LY Lian, GCK Roberts
Biochemistry 36 (7), 1567-1572, 1997
TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies
M MacFarlane, SL Kohlhaas, MJ Sutcliffe, MJS Dyer, GM Cohen
Cancer research 65 (24), 11265-11270, 2005
A new conceptual framework for enzyme catalysis: Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes
MJ Sutcliffe, NS Scrutton
European Journal of Biochemistry 269 (13), 3096-3102, 2002
The catalytic mechanism of cytochrome P450 BM3 involves a 6 movement of the bound substrate on reduction
S Modi, MJ Sutcliffe, WU Primrose, LY Lian, GCK Roberts
Nature structural biology 3 (5), 414-417, 1996
Structure of hen lysozyme in solution
LJ Smith, MJ Sutcliffe, C Redfield, CM Dobson
Journal of molecular biology 229 (4), 930-944, 1993
Analysis of. vphi. and. chi. 1 torsion angles for hen lysozyme in solution from proton NMR spin-spin coupling constants
LJ Smith, MJ Sutcliffe, C Redfield, CM Dobson
Biochemistry 30 (4), 986-996, 1991
Biodiversity of cytochrome P450 redox systems
KJ McLean, M Sabri, KR Marshall, RJ Lawson, DG Lewis, D Clift, ...
Biochemical Society Transactions 33 (4), 796-801, 2005
[23] Protein-ligand interactions: Exchange processes and determination of ligand conformation and protein-ligand contacts
LY Lian, IL Barsukov, MJ Sutcliffe, KH Sze, GCK Roberts
Methods in enzymology 239, 657-700, 1994
Drug block of the hERG potassium channel: insight from modeling
PJ Stansfeld, P Gedeck, M Gosling, B Cox, JS Mitcheson, MJ Sutcliffe
Proteins: Structure, Function, and Bioinformatics 68 (2), 568-580, 2007
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