| T-cell-antigen recognition and the immunological synapse JB Huppa, MM Davis Nature Reviews Immunology 3 (12), 973-983, 2003 | 833 | 2003 |
| TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation BF Lillemeier, MA Mörtelmaier, MB Forstner, JB Huppa, JT Groves, ... Nature immunology 11 (1), 90-96, 2010 | 683 | 2010 |
| T cell killing does not require the formation of a stable mature immunological synapse MA Purbhoo, DJ Irvine, JB Huppa, MM Davis Nature immunology 5 (5), 524-530, 2004 | 674 | 2004 |
| TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity JB Huppa, M Axmann, MA Mörtelmaier, BF Lillemeier, EW Newell, ... Nature 463 (7283), 963-967, 2010 | 566 | 2010 |
| Continuous T cell receptor signaling required for synapse maintenance and full effector potential JB Huppa, M Gleimer, C Sumen, MM Davis Nature immunology 4 (8), 749-755, 2003 | 547 | 2003 |
| Agonist/endogenous peptide–MHC heterodimers drive T cell activation and sensitivity M Krogsgaard, Q Li, C Sumen, JB Huppa, M Huse, MM Davis Nature 434 (7030), 238-243, 2005 | 437 | 2005 |
| CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse QJ Li, AR Dinner, S Qi, DJ Irvine, JB Huppa, MM Davis, AK Chakraborty Nature immunology 5 (8), 791-799, 2004 | 323 | 2004 |
| Distinct TCR signaling pathways drive proliferation and cytokine production in T cells CS Guy, KM Vignali, J Temirov, ML Bettini, AE Overacre, M Smeltzer, ... Nature immunology 14 (3), 262-270, 2013 | 275 | 2013 |
| A mouse cytomegalovirus glycoprotein, gp34, forms a complex with folded class I MHC molecules in the ER which is not retained but is transported to the cell surface MF Kleijnen, JB Huppa, P Lucin, S Mukherjee, H Farrell, AE Campbell, ... The EMBO journal, 1997 | 258 | 1997 |
| The α chain of the T cell antigen receptor is degraded in the cytosol JB Huppa, HL Ploegh Immunity 7 (1), 113-122, 1997 | 195 | 1997 |
| Assessment of costimulation and coinhibition in a triple parameter T cell reporter line: Simultaneous measurement of NF-κB, NFAT and AP-1 S Jutz, J Leitner, K Schmetterer, I Doel-Perez, O Majdic, ... Journal of immunological methods 430, 10-20, 2016 | 193 | 2016 |
| T cells as a self-referential, sensory organ MM Davis, M Krogsgaard, M Huse, J Huppa, BF Lillemeier, Q Li Annu. Rev. Immunol. 25 (1), 681-695, 2007 | 170 | 2007 |
| SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses B Agerer, M Koblischke, V Gudipati, LF Montaño-Gutierrez, M Smyth, ... Science immunology 6 (57), eabg6461, 2021 | 167 | 2021 |
| Monomeric TCRs drive T cell antigen recognition M Brameshuber, F Kellner, BK Rossboth, H Ta, K Alge, E Sevcsik, ... Nature immunology 19 (5), 487-496, 2018 | 149 | 2018 |
| Dynamics of cell surface molecules during T cell recognition MM Davis, M Krogsgaard, JB Huppa, C Sumen, MA Purbhoo, DJ Irvine, ... Annual review of biochemistry 72 (1), 717-742, 2003 | 148 | 2003 |
| Dislocation of type I membrane proteins from the ER to the cytosol is sensitive to changes in redox potential D Tortorella, CM Story, JB Huppa, EJHJ Wiertz, TR Jones, HL Ploegh The Journal of cell biology 142 (2), 365-376, 1998 | 144 | 1998 |
| Linker for activation of T cells, ζ-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center … MR Kuhné, J Lin, D Yablonski, MN Mollenauer, LIR Ehrlich, J Huppa, ... The Journal of Immunology 171 (2), 860-866, 2003 | 142 | 2003 |
| RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics E Salzer, D Cagdas, M Hons, EM Mace, W Garncarz, ÖY Petronczki, ... Nature immunology 17 (12), 1352-1360, 2016 | 133 | 2016 |
| Inefficient CAR-proximal signaling blunts antigen sensitivity V Gudipati, J Rydzek, I Doel-Perez, VDR Gonçalves, L Scharf, ... Nature immunology 21 (8), 848-856, 2020 | 132 | 2020 |
| TCRs are randomly distributed on the plasma membrane of resting antigen-experienced T cells B Rossboth, AM Arnold, H Ta, R Platzer, F Kellner, JB Huppa, ... Nature immunology 19 (8), 821-827, 2018 | 119 | 2018 |
Mark M. DavisStanford UniversityGeverifieerd e-mailadres voor stanford.edu
