| Vimentin is a novel AKT1 target mediating motility and invasion QS Zhu, K Rosenblatt, KL Huang, G Lahat, R Brobey, S Bolshakov, ... Oncogene 30 (4), 457-470, 2011 | 259 | 2011 |
| Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies G Lahat, QS Zhu, KL Huang, S Wang, S Bolshakov, J Liu, K Torres, ... PloS one 5 (4), e10105, 2010 | 222 | 2010 |
| The integrator complex attenuates promoter-proximal transcription at protein-coding genes ND Elrod, T Henriques, KL Huang, DC Tatomer, JE Wilusz, EJ Wagner, ... Molecular cell 76 (5), 738-752. e7, 2019 | 160 | 2019 |
| Nongenomic androgen activation of phosphatidylinositol 3‐kinase/Akt signaling pathway in MC3T3‐E1 osteoblasts HY Kang, CL Cho, KL Huang, JC Wang, YC Hu, HK Lin, C Chang, ... Journal of Bone and Mineral Research 19 (7), 1181-1190, 2004 | 157 | 2004 |
| The Integrator complex cleaves nascent mRNAs to attenuate transcription DC Tatomer, ND Elrod, D Liang, MS Xiao, JZ Jiang, M Jonathan, ... Genes & development 33 (21-22), 1525-1538, 2019 | 125 | 2019 |
| Integrator recruits protein phosphatase 2A to prevent pause release and facilitate transcription termination KL Huang, D Jee, CB Stein, ND Elrod, T Henriques, LG Mascibroda, ... Molecular cell 80 (2), 345-358. e9, 2020 | 115 | 2020 |
| An atlas of alternative polyadenylation quantitative trait loci contributing to complex trait and disease heritability L Li, KL Huang, Y Gao, Y Cui, G Wang, ND Elrod, Y Li, YE Chen, P Ji, ... Nature genetics 53 (7), 994-1005, 2021 | 103 | 2021 |
| Integrator subunit 4 is a ‘Symplekin-like’scaffold that associates with INTS9/11 to form the Integrator cleavage module TR Albrecht, SP Shevtsov, Y Wu, LG Mascibroda, NJ Peart, KL Huang, ... Nucleic acids research 46 (8), 4241-4255, 2018 | 71 | 2018 |
| Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate KL Huang, AB Chadee, CYA Chen, Y Zhang, AB Shyu Rna 19 (3), 295-305, 2013 | 58 | 2013 |
| Dual targeting of mTOR and aurora-A kinase for the treatment of uterine Leiomyosarcoma KJ Brewer Savannah, EG Demicco, K Lusby, MPH Ghadimi, R Belousov, ... Clinical Cancer Research 18 (17), 4633-4645, 2012 | 54 | 2012 |
| Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci CB Stein, AR Field, CA Mimoso, CC Zhao, KL Huang, EJ Wagner, ... Molecular cell 82 (22), 4232-4245. e11, 2022 | 46 | 2022 |
| Src family kinases mediate betel quid-induced oral cancer cell motility and could be a biomarker for early invasion in oral squamous cell carcinoma JYF Chen, CC Hung, KL Huang, YT Chen, SY Liu, WF Chiang, HR Chen, ... Neoplasia 10 (12), 1393-1401, 2008 | 33 | 2008 |
| Tob2 phosphorylation regulates global mRNA turnover to reshape transcriptome and impact cell proliferation CYA Chen, K Strouz, KL Huang, AB Shyu Rna 26 (9), 1143-1159, 2020 | 18 | 2020 |
| Inositol hexakisphosphate is required for Integrator function MH Lin, MK Jensen, ND Elrod, KL Huang, KA Welle, EJ Wagner, L Tong Nature communications 13 (1), 5742, 2022 | 14 | 2022 |
| Poly (ADP) ribose polymerase inhibition: A potential treatment of malignant peripheral nerve sheath tumor CM Kivlin, KL Watson, GA Al Sannaa, R Belousov, DR Ingram, KL Huang, ... Cancer Biology & Therapy 17 (2), 129-138, 2016 | 14 | 2016 |
| Expression of'drugable'tyrosine kinase receptors in malignant peripheral nerve sheath tumour: potential molecular therapeutic targets for a chemoresistant cancer. KE Torres, J Liu, E Young, KL Huang, M Ghadimi, K Lusby, AJ Lazar, ... Histopathology, 156-159, 2011 | 14 | 2011 |
| INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex LG Mascibroda, M Shboul, ND Elrod, L Colleaux, H Hamamy, KL Huang, ... Nature communications 13 (1), 6054, 2022 | 12 | 2022 |
| INTS13 Mutations Causing a Developmental Ciliopathy Disrupt Integrator Complex Assembly LG Mascibroda, M Shboul, ND Elrod, L Colleaux, H Hamamy, KL Huang, ... bioRxiv, 2020.07. 20.209130, 2020 | 10 | 2020 |
| Alternative polyadenylation alters protein dosage by switching between intronic and 3′ UTR sites N de Prisco, C Ford, ND Elrod, W Lee, LC Tang, KL Huang, A Lin, P Ji, ... Science advances 9 (7), eade4814, 2023 | 9 | 2023 |
| The Integrator complex terminates promoter-proximal transcription at protein-coding genes ND Elrod, T Henriques, KL Huang, DC Tatomer, JE Wilusz, EJ Wagner, ... bioRxiv, 725507, 2019 | 3 | 2019 |
