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Doreen Matthies
Doreen Matthies
Principal Investigator, NICHD, NIH
Geverifieerd e-mailadres voor nih.gov - Homepage
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2.2 Ċ resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor
A Bartesaghi, A Merk, S Banerjee, D Matthies, X Wu, JLS Milne, ...
Science 348 (6239), 1147-1151, 2015
5782015
Neuron-astrocyte metabolic coupling protects against activity-induced fatty acid toxicity
MS Ioannou, J Jackson, SH Sheu, CL Chang, AV Weigel, H Liu, ...
Cell 177 (6), 1522-1535. e14, 2019
5342019
Structure of β-galactosidase at 3.2-Ċ resolution obtained by cryo-electron microscopy
A Bartesaghi, D Matthies, S Banerjee, A Merk, S Subramaniam
Proceedings of the National Academy of Sciences 111 (32), 11709-11714, 2014
2272014
Cryo-EM structures of the magnesium channel CorA reveal symmetry break upon gating
D Matthies, O Dalmas, MJ Borgnia, PK Dominik, A Merk, P Rao, ...
Cell 164 (4), 747-756, 2016
1312016
Cell-free expression and assembly of ATP synthase
D Matthies, S Haberstock, F Joos, V Dötsch, J Vonck, F Bernhard, T Meier
Journal of molecular biology 413 (3), 593-603, 2011
1072011
Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs
D Matthies, C Bae, GES Toombes, T Fox, A Bartesaghi, S Subramaniam, ...
Elife 7, e37558, 2018
1052018
The structural basis of Rubisco phase separation in the pyrenoid
S He, HT Chou, D Matthies, T Wunder, MT Meyer, N Atkinson, ...
Nature plants 6 (12), 1480-1490, 2020
982020
A tridecameric c ring of the adenosine triphosphate (ATP) synthase from the thermoalkaliphilic Bacillus sp. strain TA2.A1 facilitates ATP synthesis at low …
T Meier, N Morgner, D Matthies, D Pogoryelov, S Keis, GM Cook, ...
Molecular microbiology 65 (5), 1181-1192, 2007
962007
The c13 ring from a thermoalkaliphilic ATP synthase reveals an extended diameter due to a special structural region
D Matthies, L Preiss, AL Klyszejko, DJ Muller, GM Cook, J Vonck, T Meier
Journal of molecular biology 388 (3), 611-618, 2009
852009
High-resolution structure and mechanism of an F/V-hybrid rotor ring in a Na+-coupled ATP synthase
D Matthies, W Zhou, AL Klyszejko, C Anselmi, Ö Yildiz, K Brandt, V Müller, ...
Nature communications 5 (1), 5286, 2014
752014
A New Type of Na+-Driven ATP Synthase Membrane Rotor with a Two-Carboxylate Ion-Coupling Motif
S Schulz, M Iglesias-Cans, A Krah, Ö Yildiz, V Leone, D Matthies, ...
PLoS Biology 11 (6), e1001596, 2013
632013
Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport
B Qiu, D Matthies, E Fortea, Z Yu, O Boudker
Science Advances 7 (10), eabf5814, 2021
482021
Using cryo-EM to map small ligands on dynamic metabolic enzymes: studies with glutamate dehydrogenase
MJ Borgnia, S Banerjee, A Merk, D Matthies, A Bartesaghi, P Rao, ...
Molecular pharmacology 89 (6), 645-651, 2016
442016
Allosteric interactions prime androgen receptor dimerization and activation
EV Wasmuth, AV Broeck, JR LaClair, EA Hoover, KE Lawrence, ...
Molecular cell 82 (11), 2021-2031. e5, 2022
352022
The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
AN Miller, PR Houlihan, E Matamala, D Cabezas-Bratesco, GY Lee, ...
Elife 12, e84477, 2023
332023
Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase
AK Puppala, RL French, D Matthies, U Baxa, S Subramaniam, ...
Scientific Reports 6 (1), 32563, 2016
232016
Microdomains form on the luminal face of neuronal extracellular vesicle membranes
D Matthies, NYJ Lee, I Gatera, HA Pasolli, X Zhao, H Liu, D Walpita, Z Liu, ...
Scientific Reports 10 (1), 11953, 2020
172020
Autolysosomal exocytosis of lipids protect neurons from ferroptosis
I Ralhan, J Chang, MJ Moulton, LD Goodman, NYJ Lee, G Plummer, ...
Journal of Cell Biology 222 (6), e202207130, 2023
162023
The crystal structure of human GlnRS provides basis for the development of neurological disorders
J Ognjenović, J Wu, D Matthies, U Baxa, S Subramaniam, J Ling, ...
Nucleic Acids Research 44 (7), 3420-3431, 2016
162016
Draft genome sequence of the thermoalkaliphilic Caldalkalibacillus thermarum strain TA2. A1
F Kalamorz, S Keis, DGG McMillan, K Olsson, JA Stanton, P Stockwell, ...
Journal of bacteriology 193 (16), 4290-4291, 2011
142011
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