| FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress Z Tothova, R Kollipara, BJ Huntly, BH Lee, DH Castrillon, DE Cullen, ... Cell 128 (2), 325-339, 2007 | 1779 | 2007 |
| Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17–producing T cell responses TL Denning, Y Wang, SR Patel, IR Williams, B Pulendran Nature immunology 8 (10), 1086-1094, 2007 | 1215 | 2007 |
| MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors BJP Huntly, H Shigematsu, K Deguchi, BH Lee, S Mizuno, N Duclos, ... Cancer cell 6 (6), 587-596, 2004 | 853 | 2004 |
| Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium NA Mabbott, DS Donaldson, H Ohno, IR Williams, A Mahajan Mucosal immunology 6 (4), 666-677, 2013 | 708 | 2013 |
| FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model LM Kelly, Q Liu, JL Kutok, IR Williams, CL Boulton, DG Gilliland Blood, The Journal of the American Society of Hematology 99 (1), 310-318, 2002 | 631 | 2002 |
| Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice. H Xu, JA Gonzalo, Y St Pierre, IR Williams, TS Kupper, RS Cotran, ... The Journal of experimental medicine 180 (1), 95-109, 1994 | 610 | 1994 |
| JAM-A regulates permeability and inflammation in the intestine in vivo MG Laukoetter, P Nava, WY Lee, EA Severson, CT Capaldo, BA Babbin, ... The Journal of experimental medicine 204 (13), 3067-3076, 2007 | 567 | 2007 |
| Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype JD Growney, H Shigematsu, Z Li, BH Lee, J Adelsperger, R Rowan, ... Blood 106 (2), 494-504, 2005 | 540 | 2005 |
| Deletion of TLR5 results in spontaneous colitis in mice M Vijay-Kumar, CJ Sanders, RT Taylor, A Kumar, JD Aitken, ... The Journal of clinical investigation 117 (12), 3909-3921, 2007 | 503 | 2007 |
| Mouse model of Noonan syndrome reveals cell type– and gene dosage–dependent effects of Ptpn11 mutation T Araki, MG Mohi, FA Ismat, RT Bronson, IR Williams, JL Kutok, W Yang, ... Nature medicine 10 (8), 849-857, 2004 | 451 | 2004 |
| PML/RARα and FLT3-ITD induce an APL-like disease in a mouse model LM Kelly, JL Kutok, IR Williams, CL Boulton, SM Amaral, DP Curley, ... Proceedings of the National Academy of Sciences 99 (12), 8283-8288, 2002 | 414 | 2002 |
| CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML) LM Kelly, JC Yu, CL Boulton, M Apatira, J Li, CM Sullivan, I Williams, ... Cancer cell 1 (5), 421-432, 2002 | 414 | 2002 |
| Stat5 is essential for the myelo-and lymphoproliferative disease induced by TEL/JAK2 J Schwaller, E Parganas, D Wang, D Cain, JC Aster, IR Williams, CK Lee, ... Molecular cell 6 (3), 693-704, 2000 | 376 | 2000 |
| CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice O Medina-Contreras, D Geem, O Laur, IR Williams, SA Lira, A Nusrat, ... The Journal of clinical investigation 121 (12), 4787-4795, 2011 | 334 | 2011 |
| Lipoxin a4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis AT Gewirtz, LS Collier-Hyams, AN Young, T Kucharzik, WJ Guilford, ... The Journal of Immunology 168 (10), 5260-5267, 2002 | 327 | 2002 |
| Transformation of hematopoietic cell lines to growth‐factor independence and induction of a fatal myelo‐and lymphoproliferative disease in mice by retrovirally transduced TEL … J Schwaller, J Frantsve, J Aster, IR Williams, MH Tomasson, TS Ross, ... The EMBO journal, 1998 | 323 | 1998 |
| RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium KA Knoop, N Kumar, BR Butler, SK Sakthivel, RT Taylor, T Nochi, H Akiba, ... The Journal of Immunology 183 (9), 5738-5747, 2009 | 321 | 2009 |
| CCR6-mediated dendritic cell activation of pathogen-specific T cells in Peyer's patches RM Salazar-Gonzalez, JH Niess, DJ Zammit, R Ravindran, A Srinivasan, ... Immunity 24 (5), 623-632, 2006 | 312 | 2006 |
| Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease IT Chan, JL Kutok, IR Williams, S Cohen, L Kelly, H Shigematsu, ... The Journal of clinical investigation 113 (4), 528-538, 2004 | 305 | 2004 |
| Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations MG Mohi, IR Williams, CR Dearolf, G Chan, JL Kutok, S Cohen, K Morgan, ... Cancer cell 7 (2), 179-191, 2005 | 303 | 2005 |
Thomas S KupperBrigham and Women's Hospital/Harvard Medical SchoolVerified email at bwh.harvard.edu
