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Yu Toyoshima
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Temporal coding of insulin action through multiplexing of the AKT pathway
H Kubota, R Noguchi, Y Toyoshima, Y Ozaki, S Uda, K Watanabe, ...
Molecular cell 46 (6), 820-832, 2012
1322012
The selective control of glycolysis, gluconeogenesis and glycogenesis by temporal insulin patterns
R Noguchi, H Kubota, K Yugi, Y Toyoshima, Y Komori, T Soga, S Kuroda
Molecular systems biology 9 (1), 664, 2013
1102013
Decoupling of receptor and downstream signals in the Akt pathway by its low-pass filter characteristics
KA Fujita, Y Toyoshima, S Uda, Y Ozaki, H Kubota, S Kuroda
Science signaling 3 (132), ra56-ra56, 2010
1002010
Reconstruction of insulin signal flow from phosphoproteome and metabolome data
K Yugi, H Kubota, Y Toyoshima, R Noguchi, K Kawata, Y Komori, S Uda, ...
Cell reports 8 (4), 1171-1183, 2014
872014
Accurate automatic detection of densely distributed cell nuclei in 3D space
Y Toyoshima, T Tokunaga, O Hirose, M Kanamori, T Teramoto, MS Jang, ...
PLoS computational biology 12 (6), e1004970, 2016
572016
Neuron ID dataset facilitates neuronal annotation for whole-brain activity imaging of C. elegans
Y Toyoshima, S Wu, M Kanamori, H Sato, MS Jang, S Oe, Y Murakami, ...
BMC biology 18, 1-20, 2020
292020
Automated detection and tracking of many cells by using 4D live-cell imaging data
T Tokunaga, O Hirose, S Kawaguchi, Y Toyoshima, T Teramoto, H Ikebata, ...
Bioinformatics 30 (12), i43-i51, 2014
292014
SPF-CellTracker: Tracking multiple cells with strongly-correlated moves using a spatial particle filter
O Hirose, S Kawaguchi, T Tokunaga, Y Toyoshima, T Teramoto, S Kuge, ...
IEEE/ACM transactions on computational biology and bioinformatics 15 (6 …, 2017
282017
Sensitivity control through attenuation of signal transfer efficiency by negative regulation of cellular signalling
Y Toyoshima, H Kakuda, KA Fujita, S Uda, S Kuroda
Nature communications 3 (1), 743, 2012
262012
Multiple sensory neurons mediate starvation-dependent aversive navigation in Caenorhabditis elegans
MS Jang, Y Toyoshima, M Tomioka, H Kunitomo, Y Iino
Proceedings of the National Academy of Sciences 116 (37), 18673-18683, 2019
232019
Glucose homeostatic law: insulin clearance predicts the progression of glucose intolerance in humans
K Ohashi, H Komada, S Uda, H Kubota, T Iwaki, H Fukuzawa, Y Komori, ...
PloS one 10 (12), e0143880, 2015
202015
Modulation of sensory information processing by a neuroglobin in Caenorhabditis elegans
S Oda, Y Toyoshima, M de Bono
Proceedings of the National Academy of Sciences 114 (23), E4658-E4665, 2017
152017
An annotation dataset facilitates automatic annotation of whole-brain activity imaging of C. elegans
Y Toyoshima, S Wu, M Kanamori, H Sato, MS Jang, S Oe, Y Murakami, ...
bioRxiv, 698241, 2019
62019
Probabilistic generative modeling and reinforcement learning extract the intrinsic features of animal behavior
K Mori, N Yamauchi, H Wang, K Sato, Y Toyoshima, Y Iino
Neural networks 145, 107-120, 2022
22022
Information Processing Mechanism Underlying a Perceptual Change by a Neuroglobin
S Oda, Y Toyoshima, M de Bono
Biophysical Journal 114 (3), 156a, 2018
22018
Different modes of stimuli delivery elicit changes in glutamate driven, experience-dependent interneuron response in C. elegans
L Mabardi, H Sato, Y Toyoshima, Y Iino, H Kunitomo
Neuroscience Research 186, 33-42, 2023
12023
Deducing ensemble dynamics and information flow from the whole-brain imaging data
Y Toyoshima, H Sato, D Nagata, M Kanamori, MS Jang, K Kuze, S Oe, ...
bioRxiv, 2022.11. 18.517011, 2022
12022
An ensemble learning approach to auto-annotation for whole-brain C. elegans imaging
S Wu, Y Toyoshima, MS Jang, M Kanamori, T Teramoto, Y Iwasaki, ...
bioRxiv, 180430, 2017
12017
Ensemble dynamics and information flow deduction from whole-brain imaging data
Y Toyoshima, H Sato, D Nagata, M Kanamori, MS Jang, K Kuze, S Oe, ...
PLOS Computational Biology 20 (3), e1011848, 2024
2024
Neuronal sensorimotor integration guiding salt concentration navigation in Caenorhabditis elegans
A Matsumoto, Y Toyoshima, C Zhang, A Isozaki, K Goda, Y Iino
Proceedings of the National Academy of Sciences 121 (5), e2310735121, 2024
2024
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Articles 1–20