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Lot de Witte
Lot de Witte
Assistant professor, Radboud UMC and Icahn School of Medicine at Mount Sinai
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New insights into the genetic etiology of Alzheimer’s disease and related dementias
C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ...
Nature genetics 54 (4), 412-436, 2022
8502022
Langerin is a natural barrier to HIV-1 transmission by Langerhans cells
L de Witte, A Nabatov, M Pion, D Fluitsma, MAWP De Jong, T de Gruijl, ...
Nature medicine 13 (3), 367-371, 2007
7972007
Microglia innately develop within cerebral organoids
PR Ormel, R Vieira de Sá, EJ Van Bodegraven, H Karst, O Harschnitz, ...
Nature communications 9 (1), 4167, 2018
4702018
Efficacy of anti-inflammatory agents to improve symptoms in patients with schizophrenia: an update
IE Sommer, R van Westrhenen, MJH Begemann, LD de Witte, S Leucht, ...
Schizophrenia bulletin 40 (1), 181-191, 2014
3802014
Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry
C Böttcher, S Schlickeiser, MAM Sneeboer, D Kunkel, A Knop, E Paza, ...
Nature neuroscience 22 (1), 78-90, 2019
3452019
Immune involvement in the pathogenesis of schizophrenia: a meta-analysis on postmortem brain studies
C Van Kesteren, H Gremmels, LD De Witte, EM Hol, AR Van Gool, ...
Translational psychiatry 7 (3), e1075-e1075, 2017
3262017
Predominant Infection of CD150+ Lymphocytes and Dendritic Cells during Measles Virus Infection of Macaques
RL De Swart, M Ludlow, L De Witte, Y Yanagi, G Van Amerongen, ...
PLoS pathogens 3 (11), e178, 2007
2932007
Longitudinal changes of telomere length and epigenetic age related to traumatic stress and post-traumatic stress disorder
MP Boks, HC van Mierlo, BPF Rutten, TRDJ Radstake, L De Witte, ...
Psychoneuroendocrinology 51, 506-512, 2015
2312015
Nonsteroidal anti-inflammatory drugs in schizophrenia: ready for practice or a good start? A meta-analysis
IE Sommer, L de Witte, M Begemann, RS Kahn
The Journal of clinical psychiatry 72 (4), 12876, 2011
2232011
Cytokine alterations in first-episode schizophrenia patients before and after antipsychotic treatment
L de Witte, J Tomasik, E Schwarz, PC Guest, H Rahmoune, RS Kahn, ...
Schizophrenia research 154 (1-3), 23-29, 2014
2172014
Syndecan-3 is a dendritic cell-specific attachment receptor for HIV-1
L de Witte, M Bobardt, U Chatterji, G Degeest, G David, TBH Geijtenbeek, ...
Proceedings of the National Academy of Sciences 104 (49), 19464-19469, 2007
2142007
Glioblastoma‐derived extracellular vesicles modify the phenotype of monocytic cells
J de Vrij, SLN Maas, KMC Kwappenberg, R Schnoor, A Kleijn, L Dekker, ...
International journal of cancer 137 (7), 1630-1642, 2015
1982015
Measles virus targets DC-SIGN to enhance dendritic cell infection
L de Witte, M Abt, S Schneider-Schaulies, Y van Kooyk, TBH Geijtenbeek
Journal of virology 80 (7), 3477-3486, 2006
1872006
Distinct roles for DC-SIGN+-dendritic cells and Langerhans cells in HIV-1 transmission
L de Witte, A Nabatov, TBH Geijtenbeek
Trends in molecular medicine 14 (1), 12-19, 2008
1722008
TNF-α and TLR agonists increase susceptibility to HIV-1 transmission by human Langerhans cells ex vivo
MAWP de Jong, L de Witte, MJ Oudhoff, SI Gringhuis, P Gallay, ...
The Journal of clinical investigation 118 (10), 3440-3452, 2008
1682008
CSF-1 controls cerebellar microglia and is required for motor function and social interaction
V Kana, FA Desland, M Casanova-Acebes, P Ayata, A Badimon, E Nabel, ...
Journal of Experimental Medicine 216 (10), 2265-2281, 2019
1562019
Cannabidiol as a potential treatment for psychosis
CD Schubart, IEC Sommer, P Fusar-Poli, L De Witte, RS Kahn, MPM Boks
European Neuropsychopharmacology 24 (1), 51-64, 2014
1482014
Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease
SR Guttikonda, L Sikkema, J Tchieu, N Saurat, RM Walsh, O Harschnitz, ...
Nature Neuroscience 24 (3), 343-354, 2021
1382021
DC-SIGN and CD150 have distinct roles in transmission of measles virus from dendritic cells to T-lymphocytes
L de Witte, RD de Vries, M van der Vlist, S Yüksel, M Litjens, RL de Swart, ...
PLoS pathogens 4 (4), e1000049, 2008
1322008
Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies
KP Lopes, GJL Snijders, J Humphrey, A Allan, MAM Sneeboer, E Navarro, ...
Nature genetics 54 (1), 4-17, 2022
1232022
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