Emergence of a single solid chiral state from a nearly racemic amino acid derivative WL Noorduin, T Izumi, A Millemaggi, M Leeman, H Meekes, ... Journal of the American Chemical Society 130 (4), 1158-1159, 2008 | 481 | 2008 |
Monodentate Phosphoramidites: A Breakthrough in Rhodium‐Catalysed Asymmetric Hydrogenation of Olefins M van den Berg, AJ Minnaard, RM Haak, M Leeman, EP Schudde, ... Advanced Synthesis & Catalysis 345 (1‐2), 308-323, 2003 | 282 | 2003 |
Attrition-enhanced deracemization in the synthesis of clopidogrel-a practical application of a new discovery MW van der Meijden, M Leeman, E Gelens, WL Noorduin, H Meekes, ... Organic Process Research & Development 13 (6), 1195-1198, 2009 | 149 | 2009 |
Complete Deracemization by Attrition‐Enhanced Ostwald Ripening Elucidated WL Noorduin, H Meekes, WJP van Enckevort, A Millemaggi, M Leeman, ... Angewandte Chemie International Edition 47 (34), 6445-6447, 2008 | 135 | 2008 |
Novel extractants for the recovery of fermentation derived lactic acid A Krzyżaniak, M Leeman, F Vossebeld, TJ Visser, B Schuur, AB de Haan Separation and purification technology 111, 82-89, 2013 | 110 | 2013 |
Complete chiral resolution using additive‐induced crystal size bifurcation during grinding WL Noorduin, P van der Asdonk, H Meekes, WJP van Enckevort, ... Angewandte Chemie 121 (18), 3328-3330, 2009 | 77 | 2009 |
Large-Scale Synthesis of the Glucosylceramide Synthase Inhibitor N-[5-(Adamantan-1-yl-methoxy)-pentyl]-1-deoxynojirimycin T Wennekes, B Lang, M Leeman, GA Marel, E Smits, M Weber, ... Organic Process Research & Development 12 (3), 414-423, 2008 | 54 | 2008 |
Structural aspects of nucleation inhibitors for diastereomeric resolutions and the relationship to Dutch resolution M Leeman, G Brasile, E Gelens, T Vries, B Kaptein, R Kellogg ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH- 47 (7), 1287, 2008 | 39 | 2008 |
Combining incompatible processes for deracemization of a Praziquantel derivative under flow conditions G Valenti, P Tinnemans, I Baglai, WL Noorduin, B Kaptein, M Leeman, ... Angewandte Chemie 133 (10), 5339-5342, 2021 | 35 | 2021 |
Resolution of omeprazole using coupled preferential crystallization: efficient separation of a nonracemizable conglomerate salt under near-equilibrium conditions JE Hein, BH Cao, MW van der Meijden, M Leeman, RM Kellogg Organic Process Research & Development 17 (6), 946-950, 2013 | 35 | 2013 |
The Strecker reaction coupled to Viedma ripening: a simple route to highly hindered enantiomerically pure amino acids I Baglai, M Leeman, K Wurst, B Kaptein, RM Kellogg, WL Noorduin Chemical communications 54 (77), 10832-10834, 2018 | 32 | 2018 |
A Viedma ripening route to an enantiopure building block for Levetiracetam and Brivaracetam I Baglai, M Leeman, RM Kellogg, WL Noorduin Organic & Biomolecular Chemistry 17 (1), 35-38, 2019 | 28 | 2019 |
Efficient Havinga–Kondepudi resolution of conglomerate amino acid derivatives by slow cooling and abrasive grinding WJP ávan Enckevort CrystEngComm 12 (7), 2051-2053, 2010 | 26 | 2010 |
The resolution of 2-hydroxy-5, 5-dimethyl-4-phenyl-1, 3, 2-dioxaphosphorinan 2-oxide (phencyphos) by preferential crystallization M Leeman, F Querniard, TR Vries, B Kaptein, RM Kellogg Organic Process Research & Development 13 (6), 1379-1381, 2009 | 19 | 2009 |
9.16 crystallization as a tool in industrial applications of asymmetric synthesis RM Kellogg, M Leeman Elsevier, 2012 | 18 | 2012 |
Family of Conglomerate-Forming Systems Composed of Chlocyphos and Alkyl-amine. Assessment of Their Resolution Performances by Using Various Modes of Preferential Crystallization A Mbodji, G Gbabode, M Sanselme, N Couvrat, M Leeman, V Dupray, ... Crystal Growth & Design 19 (9), 5173-5183, 2019 | 14 | 2019 |
Evidence of conglomerate with partial solid solutions in ethylammonium chlocyphos A Mbodji, G Gbabode, M Sanselme, Y Cartigny, N Couvrat, M Leeman, ... Crystal Growth & Design 20 (4), 2562-2569, 2020 | 13 | 2020 |
Performance analysis and model-free design of deracemization via temperature cycles F Breveglieri, I Baglai, M Leeman, WL Noorduin, RM Kellogg, M Mazzotti Organic Process Research & Development 24 (8), 1515-1522, 2020 | 12 | 2020 |
A chiral switch: balancing between equilibrium and non-equilibrium states I Baglai, M Leeman, B Kaptein, RM Kellogg, WL Noorduin Chemical communications 55 (48), 6910-6913, 2019 | 11 | 2019 |
Enantiospecific solid solution formation triggers the propagation of homochirality I Baglai, M Leeman, K Wurst, RM Kellogg, WL Noorduin Angewandte Chemie 132 (47), 21071-21075, 2020 | 10 | 2020 |