Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 1542* | 2021 |
Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases S Sanna, NR van Zuydam, A Mahajan, A Kurilshikov, A Vich Vila, U Võsa, ... Nature genetics 51 (4), 600-605, 2019 | 1225 | 2019 |
Large-scale association analyses identify host factors influencing human gut microbiome composition A Kurilshikov, C Medina-Gomez, R Bacigalupe, D Radjabzadeh, J Wang, ... Nature genetics 53 (2), 156-165, 2021 | 1219 | 2021 |
Gene co-expression analysis for functional classification and gene–disease predictions S Van Dam, U Vosa, A van der Graaf, L Franke, JP de Magalhaes Briefings in bioinformatics 19 (4), 575-592, 2018 | 1073 | 2018 |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ... Nature genetics 51 (2), 245-257, 2019 | 665 | 2019 |
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ... Nature genetics 48 (9), 1043-1048, 2016 | 630 | 2016 |
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals L Folkersen, S Gustafsson, Q Wang, DH Hansen, ÅK Hedman, A Schork, ... Nature metabolism 2 (10), 1135-1148, 2020 | 468 | 2020 |
Genome analyses of> 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders S Ligthart, A Vaez, U Võsa, MG Stathopoulou, PS De Vries, BP Prins, ... The American Journal of Human Genetics 103 (5), 691-706, 2018 | 396 | 2018 |
Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood T Qi, Y Wu, J Zeng, F Zhang, A Xue, L Jiang, Z Zhu, K Kemper, L Yengo, ... Nature communications 9 (1), 2282, 2018 | 358 | 2018 |
Human disease-associated genetic variation impacts large intergenic non-coding RNA expression V Kumar, HJ Westra, J Karjalainen, DV Zhernakova, T Esko, B Hrdlickova, ... PLoS genetics 9 (1), e1003201, 2013 | 351 | 2013 |
Endothelial TLR4 and the microbiome drive cerebral cavernous malformations AT Tang, JP Choi, JJ Kotzin, Y Yang, CC Hong, N Hobson, R Girard, ... Nature 545 (7654), 305-310, 2017 | 305 | 2017 |
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets JH Zhao, D Stacey, N Eriksson, E Macdonald-Dunlop, ÅK Hedman, ... Nature immunology 24 (9), 1540-1551, 2023 | 260 | 2023 |
Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers S Altmäe, M Koel, U Võsa, P Adler, M Suhorutšenko, T Laisk-Podar, ... Scientific reports 7 (1), 10077, 2017 | 247 | 2017 |
Meta‐analysis of microRNA expression in lung cancer U Vosa, T Vooder, R Kolde, J Vilo, A Metspalu, T Annilo International journal of cancer 132 (12), 2884-2893, 2013 | 247 | 2013 |
A cross-disorder dosage sensitivity map of the human genome RL Collins, JT Glessner, E Porcu, M Lepamets, R Brandon, C Lauricella, ... Cell 185 (16), 3041-3055. e25, 2022 | 222 | 2022 |
High-throughput identification of human SNPs affecting regulatory element activity J van Arensbergen, L Pagie, VD FitzPatrick, M de Haas, MP Baltissen, ... Nature genetics 51 (7), 1160-1169, 2019 | 193 | 2019 |
Identification of miR‐374a as a prognostic marker for survival in patients with early‐stage nonsmall cell lung cancer U Võsa, T Vooder, R Kolde, K Fischer, K Välk, N Tõnisson, R Roosipuu, ... Genes, Chromosomes and Cancer 50 (10), 812-822, 2011 | 161 | 2011 |
Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses OB Bakker, R Aguirre-Gamboa, S Sanna, M Oosting, SP Smeekens, ... Nature immunology 19 (7), 776-786, 2018 | 131 | 2018 |
Genetic analysis of over half a million people characterises C-reactive protein loci S Said, R Pazoki, V Karhunen, U Võsa, S Ligthart, B Bodinier, ... Nature communications 13 (1), 2198, 2022 | 105 | 2022 |
Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome DV Zhernakova, TH Le, A Kurilshikov, B Atanasovska, MJ Bonder, ... Nature genetics 50 (11), 1524-1532, 2018 | 104 | 2018 |