John F. Reilly, Ph.D.
John F. Reilly, Ph.D.
Entrepreneur-in-Residence at Apple Tree Partners
Adresse e-mail validée de appletreepartners.com
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Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)
M Duvic, R Talpur, X Ni, C Zhang, P Hazarika, C Kelly, JH Chiao, JF Reilly, ...
Blood 109 (1), 31-39, 2007
11442007
Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes
G Garcia-Manero, H Yang, C Bueso-Ramos, A Ferrajoli, J Cortes, ...
Blood, The Journal of the American Society of Hematology 111 (3), 1060-1066, 2008
4992008
Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study
E Galanis, KA Jaeckle, MJ Maurer, JM Reid, MM Ames, JS Hardwick, ...
Journal of clinical oncology 27 (12), 2052, 2009
3342009
Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study
E Galanis, KA Jaeckle, MJ Maurer, JM Reid, MM Ames, JS Hardwick, ...
Journal of clinical oncology 27 (12), 2052, 2009
3312009
Importin β–mediated nuclear import of fibroblast growth factor receptor: role in cell proliferation
JF Reilly, PA Maher
The Journal of cell biology 152 (6), 1307-1312, 2001
2552001
Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis
JM Redwine, B Kosofsky, RE Jacobs, D Games, JF Reilly, JH Morrison, ...
Proceedings of the National Academy of Sciences 100 (3), 1381-1386, 2003
2132003
Adult mouse brain gene expression patterns bear an embryologic imprint
MA Zapala, I Hovatta, JA Ellison, L Wodicka, JA Del Rio, R Tennant, ...
Proceedings of the National Academy of Sciences 102 (29), 10357-10362, 2005
1832005
Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma
VR Fantin, A Loboda, CP Paweletz, RC Hendrickson, JW Pierce, JA Roth, ...
Cancer research 68 (10), 3785-3794, 2008
1772008
Met activation in non-small cell lung cancer is associated with de novo resistance to EGFR inhibitors and the development of brain metastasis
E Benedettini, LM Sholl, M Peyton, J Reilly, C Ware, L Davis, N Vena, ...
The American journal of pathology 177 (1), 415-423, 2010
1742010
Amyloid deposition in the hippocampus and entorhinal cortex: quantitative analysis of a transgenic mouse model
JF Reilly, D Games, RE Rydel, S Freedman, D Schenk, WG Young, ...
Proceedings of the National Academy of Sciences 100 (8), 4837-4842, 2003
1642003
Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks
D Palmieri, PR Lockman, FC Thomas, E Hua, J Herring, E Hargrave, ...
Clinical Cancer Research 15 (19), 6148-6157, 2009
1512009
Regulation of astrocyte GFAP expression by TGF‐β1 and FGF‐2
JF Reilly, PA Maher, VG Kumari
Glia 22 (2), 202-210, 1998
1261998
Downregulation of Notch pathway by a γ-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model
CL Efferson, CT Winkelmann, C Ware, T Sullivan, S Giampaoli, ...
Cancer research 70 (6), 2476-2484, 2010
1002010
Alterations in fibroblast growth factor receptor expression following brain injury
JF Reilly, VG Kumari
Experimental neurology 140 (2), 139-150, 1996
921996
Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer
W Zhang, J Zhu, CL Efferson, C Ware, J Tammam, M Angagaw, J Laskey, ...
Cancer research 69 (18), 7466-7472, 2009
882009
MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor
BS Pan, GKY Chan, M Chenard, A Chi, LJ Davis, SV Deshmukh, JB Gibbs, ...
Cancer research 70 (4), 1524-1533, 2010
822010
Down‐regulation of the Notch pathway mediated by a γ‐secretase inhibitor induces anti‐tumour effects in mouse models of T‐cell leukaemia
J Tammam, C Ware, C Efferson, J O'neil, S Rao, X Qu, J Gorenstein, ...
British journal of pharmacology 158 (5), 1183-1195, 2009
802009
Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14: characterization of a new receptor binding partner
JF Reilly, G Mickey, PA Maher
Journal of Biological Chemistry 275 (11), 7771-7778, 2000
762000
Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14: characterization of a new receptor binding partner
JF Reilly, G Mickey, PA Maher
Journal of Biological Chemistry 275 (11), 7771-7778, 2000
762000
Phase I study of accelerated conformal radiotherapy for stage I non–small-cell lung cancer in patients with pulmonary dysfunction: CALGB 39904
JA Bogart, L Hodgson, SL Seagren, AW Blackstock, X Wang, R Lenox, ...
Journal of clinical oncology 28 (2), 202, 2010
702010
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