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George Tsokos
George Tsokos
Harvard Medical School
Verified email at bidmc.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Heat shock protein 70 kDa: molecular biology, biochemistry, and physiology
JG Kiang, GC Tsokos
Pharmacology & therapeutics 80 (2), 183-201, 1998
16221998
New insights into the immunopathogenesis of systemic lupus erythematosus
GC Tsokos, MS Lo, PC Reis, KE Sullivan
Nature Reviews Rheumatology 12 (12), 716-730, 2016
10972016
Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys
JC Crispín, M Oukka, G Bayliss, RA Cohen, CA Van Beek, IE Stillman, ...
The journal of immunology 181 (12), 8761-8766, 2008
9042008
Interleukin-17 and systemic lupus erythematosus: current concepts
A Nalbandian, JC Crispin, GC Tsokos
Clinical & Experimental Immunology 157 (2), 209-215, 2009
5132009
Pathogenesis of human systemic lupus erythematosus: recent advances
JC Crispín, SNC Liossis, K Kis-Toth, LA Lieberman, VC Kyttaris, YT Juang, ...
Trends in molecular medicine 16 (2), 47-57, 2010
4952010
T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with …
S Shivakumar, GC Tsokos, SK Datta
Journal of immunology (Baltimore, Md.: 1950) 143 (1), 103-112, 1989
4631989
Pathogenesis of human systemic lupus erythematosus: a cellular perspective
VR Moulton, A Suarez-Fueyo, E Meidan, H Li, M Mizui, GC Tsokos
Trends in molecular medicine 23 (7), 615-635, 2017
4102017
Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta …
SN Liossis, XZ Ding, GJ Dennis, GC Tsokos
The Journal of clinical investigation 101 (7), 1448-1457, 1998
4051998
Autoimmunity and organ damage in systemic lupus erythematosus
GC Tsokos
Nature immunology 21 (6), 605-614, 2020
3682020
The role of IL-23/IL-17 axis in lupus nephritis
Z Zhang, VC Kyttaris, GC Tsokos
The Journal of Immunology 183 (5), 3160-3169, 2009
3562009
Efficacy and safety of ustekinumab, an IL-12 and IL-23 inhibitor, in patients with active systemic lupus erythematosus: results of a multicentre, double-blind, phase 2 …
RF van Vollenhoven, BH Hahn, GC Tsokos, CL Wagner, P Lipsky, ...
The Lancet 392 (10155), 1330-1339, 2018
3232018
systemic lupus erythematosus
RG Lahita, G Tsokos, J Buyon, K Takao
3102010
B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events.
SN Liossis, B Kovacs, G Dennis, GM Kammer, GC Tsokos
The Journal of clinical investigation 98 (11), 2549-2557, 1996
3021996
T cells as therapeutic targets in SLE
JC Crispín, VC Kyttaris, C Terhorst, GC Tsokos
Nature Reviews Rheumatology 6 (6), 317-325, 2010
2942010
Regulatory T cells in the treatment of disease
A Sharabi, MG Tsokos, Y Ding, TR Malek, D Klatzmann, GC Tsokos
Nature reviews Drug discovery 17 (11), 823-844, 2018
2792018
Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV
YT Juang, Y Wang, EE Solomou, Y Li, C Mawrin, K Tenbrock, VC Kyttaris, ...
The Journal of clinical investigation 115 (4), 996-1005, 2005
2682005
Immunopathogenesis and spectrum of infections in systemiclupus erythematosus
AG Iliopoulos, GC Tsokos
Seminars in arthritis and rheumatism 25 (5), 318-336, 1996
2621996
Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: isolation of CD4-8-T helper cell lines that express the gamma delta T …
S Rajagopalan, T Zordan, GC Tsokos, SK Datta
Proceedings of the National Academy of Sciences 87 (18), 7020-7024, 1990
2521990
Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification
ME Munroe, R Lu, YD Zhao, DA Fife, JM Robertson, JM Guthridge, ...
Annals of the rheumatic diseases 75 (11), 2014-2021, 2016
2432016
Mechanisms of immune complex–mediated neutrophil recruitment and tissue injury
TN Mayadas, GC Tsokos, N Tsuboi
Circulation 120 (20), 2012-2024, 2009
2422009
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