Long-term culture of genome-stable bipotent stem cells from adult human liver M Huch, H Gehart, R Van Boxtel, K Hamer, F Blokzijl, MMA Verstegen, ... Cell 160 (1), 299-312, 2015 | 1576 | 2015 |
Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice H Azuma, N Paulk, A Ranade, C Dorrell, M Al-Dhalimy, E Ellis, S Strom, ... Nature biotechnology 25 (8), 903-910, 2007 | 924 | 2007 |
Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease CC Bell, DFG Hendriks, SML Moro, E Ellis, J Walsh, A Renblom, ... Scientific reports 6 (1), 25187, 2016 | 707 | 2016 |
Differentiation and transplantation of human embryonic stem cell–derived hepatocytes H Basma, A Soto–Gutiérrez, GR Yannam, L Liu, R Ito, T Yamamoto, ... Gastroenterology 136 (3), 990-999. e4, 2009 | 607 | 2009 |
Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells N Marquardt, V Béziat, S Nyström, J Hengst, MA Ivarsson, E Kekäläinen, ... The Journal of Immunology 194 (6), 2467-2471, 2015 | 280 | 2015 |
Present status and perspectives of cell-based therapies for liver diseases A Nussler, S Konig, M Ott, E Sokal, B Christ, W Thasler, M Brulport, ... Journal of hepatology 45 (1), 144-159, 2006 | 280 | 2006 |
Overexpression of cholesterol 7α‐hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis T Li, M Matozel, S Boehme, B Kong, LM Nilsson, G Guo, E Ellis, ... Hepatology 53 (3), 996-1006, 2011 | 257 | 2011 |
Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity—implications for therapeutic targeting of Nrf2 A Olayanju, IM Copple, HK Bryan, GT Edge, RL Sison, MW Wong, ZQ Lai, ... Free Radical Biology and Medicine 78, 202-212, 2015 | 234 | 2015 |
GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRβ in the hepatic acute phase response N Venteclef, T Jakobsson, A Ehrlund, A Damdimopoulos, L Mikkonen, ... Genes & development 24 (4), 381-395, 2010 | 233 | 2010 |
Improving the techniques for human hepatocyte transplantation: report from a consensus meeting in London J Puppi, SC Strom, RD Hughes, S Bansal, JV Castell, I Dagher, ECS Ellis, ... Cell transplantation 21 (1), 1-10, 2012 | 231 | 2012 |
Isolation of amniotic epithelial stem cells T Miki, F Marongiu, K Dorko, ECS Ellis, SC Strom Current protocols in stem cell biology 12 (1), 1E. 3.1-1E. 3.10, 2010 | 222 | 2010 |
Hepatic differentiation of amniotic epithelial cells F Marongiu, R Gramignoli, K Dorko, T Miki, AR Ranade, M Paola Serra, ... Hepatology 53 (5), 1719-1729, 2011 | 191 | 2011 |
A novel bile acid-activated vitamin D receptor signaling in human hepatocytes S Han, T Li, E Ellis, S Strom, JYL Chiang Molecular endocrinology 24 (6), 1151-1164, 2010 | 166 | 2010 |
Hepatocyte transplantation for inherited metabolic diseases of the liver C Jorns, EC Ellis, G Nowak, B Fischler, A Nemeth, SC Strom, BG Ericzon Journal of internal medicine 272 (3), 201-223, 2012 | 155 | 2012 |
Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin–proteasomal degradation J Miao, Z Xiao, D Kanamaluru, G Min, PM Yau, TD Veenstra, E Ellis, ... Genes & development 23 (8), 986-996, 2009 | 147 | 2009 |
Mouse model of Alagille syndrome and mechanisms of Jagged1 missense mutations ER Andersson, IV Chivukula, S Hankeova, M Sjöqvist, YL Tsoi, ... Gastroenterology 154 (4), 1080-1095, 2018 | 133 | 2018 |
Spatial Transcriptomics to define transcriptional patterns of zonation and structural components in the mouse liver F Hildebrandt, A Andersson, S Saarenpää, L Larsson, N Van Hul, ... Nature communications 12 (1), 7046, 2021 | 122 | 2021 |
Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation VM Lauschke, SU Vorrink, SML Moro, F Rezayee, Å Nordling, ... Hepatology 64 (5), 1743-1756, 2016 | 120 | 2016 |
Identification of oxysterol 7α-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor α (RORα)(NR1F1) target gene and a functional cross-talk between RORα and liver X … T Wada, HS Kang, M Angers, H Gong, S Bhatia, S Khadem, S Ren, E Ellis, ... Molecular pharmacology 73 (3), 891-899, 2008 | 118 | 2008 |
Insulin regulation of cholesterol 7α-hydroxylase expression in human hepatocytes: roles of forkhead box O1 and sterol regulatory element-binding protein 1c T Li, X Kong, E Owsley, E Ellis, S Strom, JYL Chiang Journal of Biological Chemistry 281 (39), 28745-28754, 2006 | 117 | 2006 |