A novel vertebrate model of Staphylococcus aureus infection reveals phagocyte‐dependent resistance of zebrafish to non‐host specialized pathogens TK Prajsnar, VT Cunliffe, SJ Foster, SA Renshaw Cellular microbiology 10 (11), 2312-2325, 2008 | 206 | 2008 |
A privileged intraphagocyte niche is responsible for disseminated infection of Staphylococcus aureus in a zebrafish model TK Prajsnar, R Hamilton, J Garcia‐Lara, G McVicker, A Williams, M Boots, ... Cellular microbiology 14 (10), 1600-1619, 2012 | 129 | 2012 |
Intracellular Staphylococcus aureus eludes selective autophagy by activating a host cell kinase Y Neumann, SA Bruns, M Rohde, TK Prajsnar, SJ Foster, I Schmitz Autophagy 12 (11), 2069-2084, 2016 | 109 | 2016 |
Identification and Characterization of σS, a Novel Component of the Staphylococcus aureus Stress and Virulence Responses LN Shaw, C Lindholm, TK Prajsnar, HK Miller, MC Brown, E Golonka, ... PloS one 3 (12), e3844, 2008 | 104 | 2008 |
Clonal Expansion during Staphylococcus aureus Infection Dynamics Reveals the Effect of Antibiotic Intervention G McVicker, TK Prajsnar, A Williams, NL Wagner, M Boots, SA Renshaw, ... PLoS pathogens 10 (2), e1003959, 2014 | 100 | 2014 |
Human skin commensals augment Staphylococcus aureus pathogenesis E Boldock, BGJ Surewaard, D Shamarina, M Na, Y Fei, A Ali, A Williams, ... Nature microbiology 3 (8), 881-890, 2018 | 99 | 2018 |
The Lysozyme-Induced Peptidoglycan N-Acetylglucosamine Deacetylase PgdA (EF1843) Is Required for Enterococcus faecalis Virulence A Benachour, R Ladjouzi, A Le Jeune, L Hébert, S Thorpe, P Courtin, ... Journal of bacteriology 194 (22), 6066-6073, 2012 | 93 | 2012 |
Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model S Masud, TK Prajsnar, V Torraca, GEM Lamers, M Benning, ... Autophagy 15 (5), 796-812, 2019 | 86 | 2019 |
A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus L Hepburn, TK Prajsnar, C Klapholz, P Moreno, CA Loynes, NV Ogryzko, ... Science 346 (6209), 641-646, 2014 | 72 | 2014 |
The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils TK Prajsnar, JJ Serba, BM Dekker, JF Gibson, S Masud, A Fleming, ... Autophagy 17 (4), 888-902, 2021 | 66 | 2021 |
A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase KD Buchan, TK Prajsnar, NV Ogryzko, NWM De Jong, M Van Gent, ... PLoS One 14 (4), e0215592, 2019 | 56 | 2019 |
RNA-seq and Tn-seq reveal fitness determinants of vancomycin-resistant Enterococcus faecium during growth in human serum X Zhang, V de Maat, AM Guzmán Prieto, TK Prajsnar, JR Bayjanov, ... BMC genomics 18, 1-12, 2017 | 49 | 2017 |
Polymersomes eradicating intracellular bacteria F Fenaroli, JD Robertson, E Scarpa, VM Gouveia, C Di Guglielmo, ... ACS nano 14 (7), 8287-8298, 2020 | 48 | 2020 |
Zebrafish as a novel vertebrate model to dissect enterococcal pathogenesis TK Prajsnar, SA Renshaw, NV Ogryzko, SJ Foster, P Serror, S Mesnage Infection and immunity 81 (11), 4271-4279, 2013 | 43 | 2013 |
Zebrafish as a new model to study effects of periodontal pathogens on cardiovascular diseases M Widziolek, TK Prajsnar, S Tazzyman, GP Stafford, J Potempa, ... Scientific reports 6 (1), 36023, 2016 | 33 | 2016 |
Existence of a colonizing Staphylococcus aureus strain isolated in diabetic foot ulcers N Messad, TK Prajsnar, G Lina, D O’Callaghan, SJ Foster, SA Renshaw, ... Diabetes 64 (8), 2991-2995, 2015 | 32 | 2015 |
Decoration of the enterococcal polysaccharide antigen EPA is essential for virulence, cell surface charge and interaction with effectors of the innate immune system RE Smith, B Salamaga, P Szkuta, N Hajdamowicz, TK Prajsnar, ... PLoS pathogens 15 (5), e1007730, 2019 | 30 | 2019 |
Guidelines for the use and interpretation of assays for monitoring autophagy 1 D Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... Autophagy 17 (1), 1-382, 2021 | 29 | 2021 |
Neutrophils use selective autophagy receptor Sqstm1/p62 to target Staphylococcus aureus for degradation in vivo in zebrafish JF Gibson, TK Prajsnar, CJ Hill, AK Tooke, JJ Serba, RD Tonge, SJ Foster, ... Autophagy 17 (6), 1448-1457, 2021 | 24 | 2021 |
Rubicon-Dependent Lc3 Recruitment to Salmonella-Containing Phagosomes Is a Host Defense Mechanism Triggered Independently From Major Bacterial … S Masud, L Van der Burg, L Storm, TK Prajsnar, AH Meijer Frontiers in cellular and infection microbiology 9, 279, 2019 | 22 | 2019 |