| Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa Y Li, YT Tsai, CW Hsu, D Erol, J Yang, WH Wu, RJ Davis, D Egli, ... Molecular medicine 18 (9), 1312, 2012 | 208 | 2012 |
| Precision Medicine: Genetic Repair of Retinitis Pigmentosa in Patient-Derived Stem Cells AG Bassuk, A Zheng, Y Li, SH Tsang, VB Mahajan Scientific reports 6, 2016 | 201 | 2016 |
| Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines J Yang, Y Li, L Chan, YT Tsai, WH Wu, HV Nguyen, CW Hsu, X Li, ... Human molecular genetics 23 (13), 3445-3455, 2014 | 105 | 2014 |
| Gene Therapy in Patient-specific Stem Cell Lines and a Preclinical Model of Retinitis Pigmentosa With Membrane Frizzled-related Protein Defects Y Li, WH Wu, CW Hsu, HV Nguyen, YT Tsai, L Chan, T Nagasaki, ... Molecular Therapy, 2014 | 94 | 2014 |
| Personalized therapeutic strategies for patients with retinitis pigmentosa A Zheng, Y Li, SH Tsang Expert opinion on biological therapy 15 (3), 391-402, 2015 | 74 | 2015 |
| Patient-specific mutations impair BESTROPHIN1’s essential role in mediating Ca2+-dependent Cl-currents in human RPE Y Li, Y Zhang, Y Xu, A Kittredge, N Ward, S Chen, SH Tsang, T Yang eLife 6, 2017 | 52 | 2017 |
| BESTROPHIN1 mutations cause defective chloride conductance in patient stem cell-derived RPE Y Moshfegh, G Velez, Y Li, AG Bassuk, VB Mahajan, SH Tsang Human Molecular Genetics, ddw126, 2016 | 52 | 2016 |
| BEST1: the Best Target for Gene and Cell Therapies T Yang, S Justus, Y Li, SH Tsang Molecular Therapy, 2015 | 51 | 2015 |
| Personalized Medicine: Cell and Gene Therapy Based on Patient-Specific iPSC-Derived Retinal Pigment Epithelium Cells Y Li, L Chan, HV Nguyen, SH Tsang Retinal Degenerative Diseases, 549-555, 2016 | 39 | 2016 |
| Patient-Specific iPSC-Derived RPE for Modeling of Retinal Diseases HV Nguyen, Y Li, SH Tsang Journal of Clinical Medicine 4 (4), 567-578, 2015 | 32 | 2015 |
| investigation and Restoration of BEST1 Activity in Patient-derived Rpes with Dominant Mutations Y Li, C Ji, A Kittredge, A Hopiavuori, N Ward, P Yao, Y Fukuda, Y Zhang, ... Scientific Reports 9 (1), 1-13, 2019 | 31 | 2019 |
| Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy KJ Wert, VB Mahajan, L Zhang, Y Yan, Y Li, J Tosi, CW Hsu, T Nagasaki, ... Signal Transduction and Targeted Therapy 1, 16005, 2016 | 27 | 2016 |
| CLIC4 regulates late endosomal trafficking and matrix degradation activity of MMP14 at focal adhesions in RPE cells KS Hsu, W Otsu, Y Li, HC Wang, S Chen, SH Tsang, JZ Chuang, ... Scientific reports 9 (1), 1-17, 2019 | 20 | 2019 |
| Skin Biopsy and Patient-Specific Stem Cell Lines Y Li, HV Nguyen, SH Tsang Patient-Specific Induced Pluripotent Stem Cell Models 1353, 77-88, 2016 | 19 | 2016 |
| HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration. S Sun, B Cai, Y Li, W Su, X Zhao, B Gong, Z Li, X Zhang, Y Wu, C Chen, ... Aging, 2019 | 18 | 2019 |
| Distinct expression requirements and rescue strategies for BEST1 loss-and gain-of-function mutations Q Zhao, Y Kong, A Kittredge, Y Li, Y Shen, Y Zhang, SH Tsang, T Yang eLife 10, e67622, 2021 | 11 | 2021 |
| Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration Y Li, YT Tsai, J Ryu, PY Su, CH Cheng, WH Wu, YS Li, PMJ Quinn, ... The American Journal of Human Genetics, 2021 | 9 | 2021 |
| Generation of induced pluripotent stem cells from conjunctiva J Yang, Y Li, D Erol, WH Wu, YT Tsai, XR Li, RJ Davis, SH Tsang Graefe's Archive for Clinical and Experimental Ophthalmology 252 (3), 423-431, 2014 | 9 | 2014 |
| HIF2α activation and mitochondrial deficit due to iron chelation cause retinal atrophy Y Kong, PK Liu, Y Li, ND Nolan, PMJ Quinn, CW Hsu, LA Jenny, J Zhao, ... EMBO Molecular Medicine 15 (2), e16525, 2023 | 6 | 2023 |
| CRISPR editing demonstrates rs10490924 raised oxidative stress in iPSC-derived retinal cells from patients with ARMS2/HTRA1-related AMD YJ Chang, LA Jenny, YS Li, X Cui, Y Kong, Y Li, JR Sparrow, SH Tsang Proceedings of the National Academy of Sciences 120 (19), e2215005120, 2023 | 5 | 2023 |
