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Stuart M Cain
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The cellular mechanisms of neuronal swelling underlying cytotoxic edema
RL Rungta, HB Choi, JR Tyson, A Malik, L Dissing-Olesen, PJC Lin, ...
Cell 161 (3), 610-621, 2015
2312015
T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures
E Tringham, KL Powell, SM Cain, K Kuplast, J Mezeyova, M Weerapura, ...
Science translational medicine 4 (121), 121ra19-121ra19, 2012
2172012
Contributions of T-type calcium channel isoforms to neuronal firing
SM Cain, TP Snutch
Channels 4 (6), 475-482, 2010
2122010
A Cav3. 2 T-type calcium channel point mutation has splice-variant-specific effects on function and segregates with seizure expression in a polygenic rat model of absence epilepsy
KL Powell, SM Cain, C Ng, S Sirdesai, LS David, M Kyi, E Garcia, ...
Journal of Neuroscience 29 (2), 371-380, 2009
2002009
T-type calcium channels in burst-firing, network synchrony, and epilepsy
SM Cain, TP Snutch
Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (7), 1572-1578, 2013
1502013
Voltage‐gated calcium channels and disease
SM Cain, TP Snutch
Biofactors 37 (3), 197-205, 2011
1202011
Brainstem spreading depolarization and cortical dynamics during fatal seizures in Cacna1a S218L mice
ICM Loonen, NA Jansen, SM Cain, M Schenke, RA Voskuyl, AC Yung, ...
Brain 142 (2), 412-425, 2019
962019
Low threshold T‐type calcium channels as targets for novel epilepsy treatments
KL Powell, SM Cain, TP Snutch, TJ O'Brien
British journal of clinical pharmacology 77 (5), 729-739, 2014
942014
Voltage-gated calcium channels in epilepsy
SM Cain, TP Snutch
Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition, 2012
692012
Splice-variant changes of the CaV3. 2 T-type calcium channel mediate voltage-dependent facilitation and associate with cardiac hypertrophy and development
LS David, E Garcia, SM Cain, E Thau, JR Tyson, TP Snutch
Channels 4 (5), 375-389, 2010
622010
Pregabalin as a pain therapeutic: beyond calcium channels
SRA Alles, SM Cain, TP Snutch
Frontiers in Cellular Neuroscience 14, 83, 2020
612020
In vivo imaging reveals that pregabalin inhibits cortical spreading depression and propagation to subcortical brain structures
SM Cain, B Bohnet, J LeDue, AC Yung, E Garcia, JR Tyson, SRA Alles, ...
Proceedings of the National Academy of Sciences 114 (9), 2401-2406, 2017
522017
CaV3.2 drives sustained burst‐firing, which is critical for absence seizure propagation in reticular thalamic neurons
SM Cain, JR Tyson, HB Choi, R Ko, PJC Lin, JM LeDue, KL Powell, ...
Epilepsia 59 (4), 778-791, 2018
512018
The X-linked intellectual disability gene Zdhhc9 is essential for dendrite outgrowth and inhibitory synapse formation
JJ Shimell, BS Shah, SM Cain, S Thouta, N Kuhlmann, I Tatarnikov, ...
Cell reports 29 (8), 2422-2437. e8, 2019
482019
Thalamocortical neurons display suppressed burst-firing due to an enhanced Ih current in a genetic model of absence epilepsy
SM Cain, JR Tyson, KL Jones, TP Snutch
Pflügers Archiv-European Journal of Physiology 467, 1367-1382, 2015
422015
mGlu4 potentiation of K2P2. 1 is dependant on C-terminal dephosphorylation
SM Cain, HJ Meadows, J Dunlop, TJ Bushell
Molecular and Cellular Neuroscience 37 (1), 32-39, 2008
422008
The Cacna1h mutation in the GAERS model of absence epilepsy enhances T-type Ca2+ currents by altering calnexin-dependent trafficking of Cav3.2 channels
J Proft, Y Rzhepetskyy, J Lazniewska, FX Zhang, SM Cain, TP Snutch, ...
Scientific reports 7 (1), 11513, 2017
412017
Epigallocatechin-3-gallate elicits Ca2+ spike in MCF-7 breast cancer cells: essential role of Cav3. 2 channels
E Ranzato, V Magnelli, S Martinotti, Z Waheed, SM Cain, TP Snutch, ...
Cell Calcium 56 (4), 285-295, 2014
372014
The T-type calcium channel antagonist Z944 rescues impairments in crossmodal and visual recognition memory in Genetic Absence Epilepsy Rats from Strasbourg
WN Marks, SM Cain, TP Snutch, JG Howland
Neurobiology of Disease 94, 106-115, 2016
352016
Sociability impairments in genetic absence epilepsy rats from Strasbourg: reversal by the T-type calcium channel antagonist Z944
MT Henbid, WN Marks, MJ Collins, SM Cain, TP Snutch, JG Howland
Experimental Neurology 296, 16-22, 2017
302017
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