The cellular mechanisms of neuronal swelling underlying cytotoxic edema RL Rungta, HB Choi, JR Tyson, A Malik, L Dissing-Olesen, PJC Lin, ... Cell 161 (3), 610-621, 2015 | 205 | 2015 |
T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures E Tringham, KL Powell, SM Cain, K Kuplast, J Mezeyova, M Weerapura, ... Science translational medicine 4 (121), 121ra19-121ra19, 2012 | 199 | 2012 |
Contributions of T-type calcium channel isoforms to neuronal firing SM Cain, TP Snutch Channels 4 (6), 475-482, 2010 | 198 | 2010 |
A Cav3. 2 T-type calcium channel point mutation has splice-variant-specific effects on function and segregates with seizure expression in a polygenic rat model of absence epilepsy KL Powell, SM Cain, C Ng, S Sirdesai, LS David, M Kyi, E Garcia, ... Journal of Neuroscience 29 (2), 371-380, 2009 | 187 | 2009 |
T-type calcium channels in burst-firing, network synchrony, and epilepsy SM Cain, TP Snutch Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (7), 1572-1578, 2013 | 145 | 2013 |
Voltage‐gated calcium channels and disease SM Cain, TP Snutch Biofactors 37 (3), 197-205, 2011 | 105 | 2011 |
Low threshold T‐type calcium channels as targets for novel epilepsy treatments KL Powell, SM Cain, TP Snutch, TJ O'Brien British journal of clinical pharmacology 77 (5), 729-739, 2014 | 81 | 2014 |
Brainstem spreading depolarization and cortical dynamics during fatal seizures in Cacna1a S218L mice ICM Loonen, NA Jansen, SM Cain, M Schenke, RA Voskuyl, AC Yung, ... Brain 142 (2), 412-425, 2019 | 77 | 2019 |
Voltage-gated calcium channels in epilepsy SM Cain, TP Snutch Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition, 2012 | 63 | 2012 |
Splice-variant changes of the CaV3. 2 T-type calcium channel mediate voltage-dependent facilitation and associate with cardiac hypertrophy and development LS David, E Garcia, SM Cain, E Thau, JR Tyson, TP Snutch Channels 4 (5), 375-389, 2010 | 59 | 2010 |
In vivo imaging reveals that pregabalin inhibits cortical spreading depression and propagation to subcortical brain structures SM Cain, B Bohnet, J LeDue, AC Yung, E Garcia, JR Tyson, SRA Alles, ... Proceedings of the National Academy of Sciences 114 (9), 2401-2406, 2017 | 45 | 2017 |
CaV3.2 drives sustained burst‐firing, which is critical for absence seizure propagation in reticular thalamic neurons SM Cain, JR Tyson, HB Choi, R Ko, PJC Lin, JM LeDue, KL Powell, ... Epilepsia 59 (4), 778-791, 2018 | 42 | 2018 |
Thalamocortical neurons display suppressed burst-firing due to an enhanced Ih current in a genetic model of absence epilepsy SM Cain, JR Tyson, KL Jones, TP Snutch Pflügers Archiv-European Journal of Physiology 467, 1367-1382, 2015 | 42 | 2015 |
Pregabalin as a pain therapeutic: beyond calcium channels SRA Alles, SM Cain, TP Snutch Frontiers in Cellular Neuroscience 14, 83, 2020 | 40 | 2020 |
mGlu4 potentiation of K2P2. 1 is dependant on C-terminal dephosphorylation SM Cain, HJ Meadows, J Dunlop, TJ Bushell Molecular and Cellular Neuroscience 37 (1), 32-39, 2008 | 40 | 2008 |
The Cacna1h mutation in the GAERS model of absence epilepsy enhances T-type Ca2+ currents by altering calnexin-dependent trafficking of Cav3.2 channels J Proft, Y Rzhepetskyy, J Lazniewska, FX Zhang, SM Cain, TP Snutch, ... Scientific reports 7 (1), 11513, 2017 | 35 | 2017 |
Epigallocatechin-3-gallate elicits Ca2+ spike in MCF-7 breast cancer cells: essential role of Cav3. 2 channels E Ranzato, V Magnelli, S Martinotti, Z Waheed, SM Cain, TP Snutch, ... Cell Calcium 56 (4), 285-295, 2014 | 35 | 2014 |
The X-linked intellectual disability gene Zdhhc9 is essential for dendrite outgrowth and inhibitory synapse formation JJ Shimell, BS Shah, SM Cain, S Thouta, N Kuhlmann, I Tatarnikov, ... Cell reports 29 (8), 2422-2437. e8, 2019 | 33 | 2019 |
The T-type calcium channel antagonist Z944 rescues impairments in crossmodal and visual recognition memory in Genetic Absence Epilepsy Rats from Strasbourg WN Marks, SM Cain, TP Snutch, JG Howland Neurobiology of Disease 94, 106-115, 2016 | 32 | 2016 |
Sociability impairments in genetic absence epilepsy rats from Strasbourg: reversal by the T-type calcium channel antagonist Z944 MT Henbid, WN Marks, MJ Collins, SM Cain, TP Snutch, JG Howland Experimental Neurology 296, 16-22, 2017 | 28 | 2017 |