Charles Swanton
Charles Swanton
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
10161*2021
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ...
N Engl j Med 366, 883-892, 2012
70242012
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ...
Science 351 (6280), 1463-1469, 2016
19542016
The causes and consequences of genetic heterogeneity in cancer evolution
RA Burrell, N McGranahan, J Bartek, C Swanton
Nature 501 (7467), 338-345, 2013
19172013
Tracking the evolution of non–small-cell lung cancer
M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ...
New England Journal of Medicine 376 (22), 2109-2121, 2017
13472017
Clonal heterogeneity and tumor evolution: past, present, and the future
N McGranahan, C Swanton
Cell 168 (4), 613-628, 2017
13442017
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
M Gerlinger, S Horswell, J Larkin, AJ Rowan, MP Salm, I Varela, R Fisher, ...
Nature genetics 46 (3), 225-233, 2014
10932014
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
EC de Bruin, N McGranahan, R Mitter, M Salm, DC Wedge, L Yates, ...
Science 346 (6206), 251-256, 2014
9392014
Renal cell carcinoma
JJ Hsieh, MP Purdue, S Signoretti, C Swanton, L Albiges, M Schmidinger, ...
Nature reviews Disease primers 3 (1), 1-19, 2017
9362017
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...
Nature 545 (7655), 446-451, 2017
9342017
Intratumor heterogeneity: evolution through space and time
C Swanton
Cancer research 72 (19), 4875-4882, 2012
8642012
Biological and therapeutic impact of intratumor heterogeneity in cancer evolution
N McGranahan, C Swanton
Cancer cell 27 (1), 15-26, 2015
8552015
Genetic prognostic and predictive markers in colorectal cancer
A Walther, E Johnstone, C Swanton, R Midgley, I Tomlinson, D Kerr
Nature Reviews Cancer 9 (7), 489-499, 2009
8502009
Cancer heterogeneity: implications for targeted therapeutics
R Fisher, L Pusztai, C Swanton
British journal of cancer 108 (3), 479-485, 2013
7752013
Replication stress links structural and numerical cancer chromosomal instability
RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ...
Nature 494 (7438), 492-496, 2013
6732013
Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic
TA Chan, M Yarchoan, E Jaffee, C Swanton, SA Quezada, A Stenzinger, ...
Annals of Oncology 30 (1), 44-56, 2019
6662019
DeconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution
R Rosenthal, N McGranahan, J Herrero, BS Taylor, C Swanton
Genome biology 17 (1), 1-11, 2016
6442016
Allele-specific HLA loss and immune escape in lung cancer evolution
N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ...
Cell 171 (6), 1259-1271. e11, 2017
5702017
Toward understanding and exploiting tumor heterogeneity
AA Alizadeh, V Aranda, A Bardelli, C Blanpain, C Bock, C Borowski, ...
Nature medicine 21 (8), 846-853, 2015
5582015
Chromosomal instability drives metastasis through a cytosolic DNA response
SF Bakhoum, B Ngo, AM Laughney, JA Cavallo, CJ Murphy, P Ly, P Shah, ...
Nature 553 (7689), 467-472, 2018
5362018
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