Nienke Vrisekoop
Nienke Vrisekoop
Assistant Professor, Laboratory of Translational Immunology, UMCU
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In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days
J Pillay, I Den Braber, N Vrisekoop, LM Kwast, RJ De Boer, ...
Blood, The Journal of the American Society of Hematology 116 (4), 625-627, 2010
Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans
I den Braber, T Mugwagwa, N Vrisekoop, L Westera, R Mögling, ...
Immunity 36 (2), 288-297, 2012
T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens
JN Mandl, JP Monteiro, N Vrisekoop, RN Germain
Immunity 38 (2), 263-274, 2013
Plasticity between epithelial and mesenchymal states unlinks EMT from metastasis-enhancing stem cell capacity
E Beerling, D Seinstra, E de Wit, L Kester, D van der Velden, C Maynard, ...
Cell reports 14 (10), 2281-2288, 2016
Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool
N Vrisekoop, I den Braber, AB de Boer, AFC Ruiter, MT Ackermans, ...
Proceedings of the National Academy of Sciences 105 (16), 6115-6120, 2008
Plasticity of Lgr5-negative cancer cells drives metastasis in colorectal cancer
A Fumagalli, KC Oost, L Kester, J Morgner, L Bornes, L Bruens, ...
Cell stem cell 26 (4), 569-578. e7, 2020
Intravital microscopy through an abdominal imaging window reveals a pre-micrometastasis stage during liver metastasis
L Ritsma, EJA Steller, E Beerling, CJM Loomans, A Zomer, C Gerlach, ...
Science translational medicine 4 (158), 158ra145-158ra145, 2012
Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naive CD4+ and CD8+ T cells
JN Mandl, R Liou, F Klauschen, N Vrisekoop, JP Monteiro, AJ Yates, ...
Proceedings of the National Academy of Sciences 109 (44), 18036-18041, 2012
Intravital microscopy: new insights into metastasis of tumors
E Beerling, L Ritsma, N Vrisekoop, PWB Derksen, J van Rheenen
Journal of cell science 124 (3), 299-310, 2011
Brief report: Intravital imaging of cancer stem cell plasticity in mammary tumors
A Zomer, SIJ Ellenbroek, L Ritsma, E Beerling, N Vrisekoop, ...
Stem cells 31 (3), 602-606, 2013
Low immune activation despite high levels of pathogenic human immunodeficiency virus type 1 results in long-term asymptomatic disease
SK Choudhary, N Vrisekoop, CA Jansen, SA Otto, H Schuitemaker, ...
Journal of virology 81 (16), 8838-8842, 2007
Neutrophil phenotypes in health and disease
P Hellebrekers, N Vrisekoop, L Koenderman
European journal of clinical investigation 48, e12943, 2018
Human CD62Ldim neutrophils identified as a separate subset by proteome profiling and in vivo pulse-chase labeling
T Tak, P Wijten, M Heeres, P Pickkers, A Scholten, AJR Heck, ...
Blood, The Journal of the American Society of Hematology 129 (26), 3476-3485, 2017
The mechanisms and physiological relevance of glycocalyx degradation in hepatic ischemia/reperfusion injury
RF van Golen, MJ Reiniers, N Vrisekoop, CJ Zuurbier, PB Olthof, ...
Antioxidants & redox signaling 21 (7), 1098-1118, 2014
On the origin of low-density neutrophils
M Hassani, P Hellebrekers, N Chen, C van Aalst, S Bongers, F Hietbrink, ...
Journal of Leukocyte Biology 107 (5), 809-818, 2020
Revisiting thymic positive selection and the mature T cell repertoire for antigen
N Vrisekoop, JP Monteiro, JN Mandl, RN Germain
Immunity 41 (2), 181-190, 2014
Differential antibacterial control by neutrophil subsets
PHC Leliefeld, J Pillay, N Vrisekoop, M Heeres, T Tak, M Kox, ...
Blood advances 2 (11), 1344-1355, 2018
Restoration of the CD4 T cell compartment after long-term highly active antiretroviral therapy without phenotypical signs of accelerated immunological aging
N Vrisekoop, R van Gent, AB de Boer, SA Otto, JCC Borleffs, ...
The Journal of Immunology 181 (2), 1573-1581, 2008
In vivo dynamics of stable chronic lymphocytic leukemia inversely correlate with somatic hypermutation levels and suggest no major leukemic turnover in bone marrow
R van Gent, AP Kater, SA Otto, A Jaspers, JAM Borghans, N Vrisekoop, ...
Cancer research 68 (24), 10137-10144, 2008
Proteolytically active ADAM10 and ADAM17 carried on membrane microvesicles in human abdominal aortic aneurysms
M Folkesson, C Li, S Frebelius, J Swedenborg, D Wågsäter, KJ Williams, ...
Thrombosis and haemostasis 114 (12), 1165-1174, 2015
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