Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry X Feng, MS Degese, R Iglesias-Bartolome, JP Vaque, AA Molinolo, ... Cancer cell 25 (6), 831-845, 2014 | 598 | 2014 |
mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis R Iglesias-Bartolome, V Patel, A Cotrim, K Leelahavanichkul, AA Molinolo, ... Cell stem cell 11 (3), 401-414, 2012 | 309 | 2012 |
Transcriptional signature primes human oral mucosa for rapid wound healing R Iglesias-Bartolome, A Uchiyama, AA Molinolo, L Abusleme, SR Brooks, ... Science translational medicine 10 (451), eaap8798, 2018 | 205 | 2018 |
A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors JP Vaqué, RT Dorsam, X Feng, R Iglesias-Bartolome, DJ Forsthoefel, ... Molecular cell 49 (1), 94-108, 2013 | 162 | 2013 |
Inactivation of a Gαs–PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis R Iglesias-Bartolome, D Torres, R Marone, X Feng, D Martin, M Simaan, ... Nature cell biology 17 (6), 793-803, 2015 | 157 | 2015 |
Assembly and activation of the Hippo signalome by FAT1 tumor suppressor D Martin, MS Degese, L Vitale-Cross, R Iglesias-Bartolome, JLC Valera, ... Nature communications 9 (1), 2372, 2018 | 147 | 2018 |
Exploiting the head and neck cancer oncogenome: widespread PI3K-mTOR pathway alterations and novel molecular targets R Iglesias-Bartolome, D Martin, JS Gutkind Cancer discovery 3 (7), 722-725, 2013 | 140 | 2013 |
mTOR Co-Targeting in Cetuximab Resistance in Head and Neck Cancers Harboring PIK3CA and RAS Mutations Z Wang, D Martin, AA Molinolo, V Patel, R Iglesias-Bartolome, ... Journal of the National Cancer Institute 106 (9), dju215, 2014 | 116 | 2014 |
YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity Y Yuan, J Park, A Feng, P Awasthi, Z Wang, Q Chen, ... Nature communications 11 (1), 1472, 2020 | 89 | 2020 |
Signaling circuitries controlling stem cell fate: to be or not to be R Iglesias-Bartolome, JS Gutkind Current opinion in cell biology 23 (6), 716-723, 2011 | 76 | 2011 |
Metabolic pathways and intracellular trafficking of gangliosides JL Daniotti, R Iglesias‐Bartolomé IUBMB life 63 (7), 513-520, 2011 | 71 | 2011 |
Expression of an active Gαs mutant in skeletal stem cells is sufficient and necessary for fibrous dysplasia initiation and maintenance X Zhao, P Deng, R Iglesias-Bartolome, P Amornphimoltham, DJ Steffen, ... Proceedings of the National Academy of Sciences 115 (3), E428-E437, 2018 | 67 | 2018 |
A biomechanical switch regulates the transition towards homeostasis in oesophageal epithelium J McGinn, A Hallou, S Han, K Krizic, S Ulyanchenko, R Iglesias-Bartolome, ... Nature Cell Biology 23 (5), 511-525, 2021 | 47 | 2021 |
mTOR inhibition prevents rapid-onset of carcinogen-induced malignancies in a novel inducible HPV-16 E6/E7 mouse model JL Callejas-Valera, R Iglesias-Bartolome, P Amornphimoltham, ... Carcinogenesis 37 (10), 1014-1025, 2016 | 44 | 2016 |
Combining portable Raman probes with nanotubes for theranostic applications AA Bhirde, G Liu, A Jin, R Iglesias-Bartolome, AA Sousa, RD Leapman, ... Theranostics 1, 310, 2011 | 44 | 2011 |
Control of the epithelial stem cell epigenome: the shaping of epithelial stem cell identity R Iglesias-Bartolome, JL Callejas-Valera, JS Gutkind Current opinion in cell biology 25 (2), 162-169, 2013 | 38 | 2013 |
The antibody to GD3 ganglioside, R24, is rapidly endocytosed and recycled to the plasma membrane via the endocytic recycling compartment: Inhibitory effect of brefeldin A and … R Iglesias‐Bartolomé, PM Crespo, GA Gomez, JL Daniotti The FEBS journal 273 (8), 1744-1758, 2006 | 36 | 2006 |
Prevention of irradiation-induced salivary hypofunction by rapamycin in swine parotid glands Z Zhu, B Pang, R Iglesias-Bartolome, X Wu, L Hu, C Zhang, J Wang, ... Oncotarget 7 (15), 20271, 2016 | 35 | 2016 |
Differential endocytic trafficking of neuropathy-associated antibodies to GM1 ganglioside and cholera toxin in epithelial and neural cells R Iglesias-Bartolomé, A Trenchi, R Comín, AL Moyano, GA Nores, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1788 (12), 2526-2540, 2009 | 35 | 2009 |
Genome‐wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy AD Sahu, J S Lee, Z Wang, G Zhang, R Iglesias‐Bartolome, T Tian, Z Wei, ... Molecular systems biology 15 (3), e8323, 2019 | 33 | 2019 |