WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research DN Slenter, M Kutmon, K Hanspers, A Riutta, J Windsor, N Nunes, ... Nucleic acids research 46 (D1), D661-D667, 2018 | 955 | 2018 |
Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification MA La Merrill, LN Vandenberg, MT Smith, W Goodson, P Browne, ... Nature Reviews Endocrinology, 2019 | 776 | 2019 |
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ... Nature communications 10 (1), 2674, 2019 | 315 | 2019 |
The key characteristics of carcinogens: relationship to the hallmarks of cancer, relevant biomarkers, and assays to measure them MT Smith, KZ Guyton, N Kleinstreuer, A Borrel, A Cardenas, WA Chiu, ... Cancer Epidemiology, Biomarkers & Prevention 29 (10), 1887-1903, 2020 | 89 | 2020 |
Aflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinoma L Rieswijk, SMH Claessen, O Bekers, M van Herwijnen, DHJ Theunissen, ... Toxicology 350, 31-39, 2016 | 85 | 2016 |
Proposed key characteristics of female reproductive toxicants as an approach for organizing and evaluating mechanistic data in hazard assessment U Luderer, B Eskenazi, R Hauser, KS Korach, CM McHale, F Moran, ... Environmental health perspectives 127 (7), 075001, 2019 | 67 | 2019 |
A data fusion pipeline for generating and enriching adverse outcome pathway descriptions P Nymark, L Rieswijk, F Ehrhart, N Jeliazkova, G Tsiliki, H Sarimveis, ... Toxicological Sciences 162 (1), 264-275, 2018 | 59 | 2018 |
Formaldehyde and brain disorders: a meta-analysis and bioinformatics approach I Rana, L Rieswijk, C Steinmaus, L Zhang Neurotoxicity research 39, 924-948, 2021 | 48 | 2021 |
Key characteristics approach to carcinogenic hazard identification KZ Guyton, L Rieswijk, A Wang, WA Chiu, MT Smith Chemical Research in Toxicology 31 (12), 1290-1292, 2018 | 40 | 2018 |
A state-of-the-science review of arsenic’s effects on glucose homeostasis in experimental models F Castriota, L Rieswijk, S Dahlberg, MA La Merrill, C Steinmaus, MT Smith, ... Environmental Health Perspectives 128 (1), 016001, 2020 | 32 | 2020 |
Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women JYY Wong, H Zhang, CA Hsiung, K Shiraishi, K Yu, K Matsuo, MP Wong, ... Genomics 112 (2), 1223-1232, 2020 | 30 | 2020 |
Human exposure to trichloroethylene is associated with increased variability of blood DNA methylation that is enriched in genes and pathways related to autoimmune disease and … RV Phillips, L Rieswijk, AE Hubbard, R Vermeulen, J Zhang, W Hu, L Li, ... Epigenetics 14 (11), 1112-1124, 2019 | 28 | 2019 |
Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes L Rieswijk, KJJ Brauers, MLJ Coonen, SGJ Van Breda, DGJ Jennen, ... Mutagenesis 30 (6), 771-784, 2015 | 26 | 2015 |
Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and … L Rieswijk, KJJ Brauers, MLJ Coonen, DGJ Jennen, SGJ van Breda, ... Mutagenesis 31 (5), 603-615, 2016 | 16 | 2016 |
Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating … L Rieswijk, D Lizarraga, KJJ Brauers, JCS Kleinjans, JHM van Delft Mutagenesis 29 (1), 17-26, 2014 | 15 | 2014 |
InContext: curation of medical context for drug indications K Moodley, L Rieswijk, TI Oprea, M Dumontier Journal of biomedical semantics 12, 1-15, 2021 | 4 | 2021 |
eNanoMapper–A database and ontology framework for design and safety assessment of nanomaterials G Kilic, B Fadeel, L Farcal, H Sarimveis, P Doganis, G Drakakis, G Tsiliki, ... Toxicology Letters 258 (September), S118-S119, 2016 | 2 | 2016 |
Answering scientific questions with linked European nanosafety data E Willighagen, M Rautenberg, D Gebele, L Rieswijk, F Ehrhart, J Chang, ... 9th International Conference Semantic Web Applications and Tools for Life …, 2016 | 2 | 2016 |
TAPS Responsibility matrix: a tool for responsible data science by design V Urovi, R Celebi, C Sun, P Kumar, L Rieswijk, M Erard, A Yilmaz, ... Journal of Responsible Innovation 11 (1), 1-32, 2024 | 1 | 2024 |
An approach to the proposal of drug combination for cancer therapy using a pathway data connectivity approach R Miller, S Muraru, AB Malpartida, J Low, MP de Almeida, B van Engelen, ... | 1 | 2022 |