Sabine Linn
Sabine Linn
Professor of Translational Oncology - Utrecht University; Group leader NKI Amsterdam
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A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
K Berns, HM Horlings, BT Hennessy, M Madiredjo, EM Hijmans, K Beelen, ...
Cancer cell 12 (4), 395-402, 2007
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
K Berns, HM Horlings, BT Hennessy, M Madiredjo, EM Hijmans, K Beelen, ...
Cancer cell 12 (4), 395-402, 2007
Molecular characterisation of soft tissue tumours: a gene expression study
TO Nielsen, RB West, SC Linn, O Alter, MA Knowling, JX O'Connell, S Zhu, ...
The Lancet 359 (9314), 1301-1307, 2002
Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial
L Voorwerk, M Slagter, HM Horlings, K Sikorska, KK van de Vijver, ...
Nature medicine 25 (6), 920-928, 2019
Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model
R Meuwissen, SC Linn, RI Linnoila, J Zevenhoven, WJ Mooi, A Berns
Cancer cell 4 (3), 181-189, 2003
10 year survival after breast-conserving surgery plus radiotherapy compared with mastectomy in early breast cancer in the Netherlands: a population-based study
MC van Maaren, L de Munck, GH de Bock, JJ Jobsen, T van Dalen, ...
The Lancet Oncology 17 (8), 1158-1170, 2016
An international validation study of the EORTC brain cancer module (EORTC QLQ-BN20) for assessing health-related quality of life and symptoms in brain cancer patients
MJB Taphoorn, L Claassens, NK Aaronson, C Coens, M Mauer, D Osoba, ...
European Journal of Cancer 46 (6), 1033-1040, 2010
Prognosis of women with primary breast cancer diagnosed during pregnancy: results from an international collaborative study
F Amant, G von Minckwitz, SN Han, M Bontenbal, AE Ring, J Giermek, ...
Journal of Clinical Oncology 31 (20), 2532-2539, 2013
Treatment of breast cancer during pregnancy: an observational study
S Loibl, SN Han, G von Minckwitz, M Bontenbal, A Ring, J Giermek, ...
The lancet oncology 13 (9), 887-896, 2012
The predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancer
M Knauer, S Mook, EJT Rutgers, RA Bender, M Hauptmann, ...
Breast cancer research and treatment 120, 655-661, 2010
Use of 70-gene signature to predict prognosis of patients with node-negative breast cancer: a prospective community-based feasibility study (RASTER)
JM Bueno-de-Mesquita, WH van Harten, VP Retel, LJ van't Veer, ...
The lancet oncology 8 (12), 1079-1087, 2007
Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer …
R Gray, R Bradley, J Braybrooke, Z Liu, R Peto, L Davies, D Dodwell, ...
The lancet 393 (10179), 1440-1452, 2019
Neoadjuvant chemotherapy with or without anthracyclines in the presence of dual HER2 blockade for HER2-positive breast cancer (TRAIN-2): a multicentre, open-label, randomised …
MS van Ramshorst, A van der Voort, ED van Werkhoven, IA Mandjes, ...
The Lancet Oncology 19 (12), 1630-1640, 2018
Effects of tamoxifen and exemestane on cognitive functioning: a study in postmenopausal
CMT Schilder
Late effects of high‐dose adjuvant chemotherapy on white and gray matter in breast cancer survivors: converging results from multimodal magnetic resonance imaging
MB de Ruiter, L Reneman, W Boogerd, DJ Veltman, M Caan, G Douaud, ...
Human brain mapping 33 (12), 2971-2983, 2012
A prospective evaluation of a breast cancer prognosis signature in the observational RASTER study
CA Drukker, JM Bueno‐de‐Mesquita, VP Retèl, WH van Harten, ...
International journal of cancer 133 (4), 929-936, 2013
Prognostic role of clinical, pathological and biological characteristics in patients with locally advanced breast cancer
AH Honkoop, PJ Van Diest, JS De Jong, SC Linn, G Giaccone, ...
British journal of cancer 77 (4), 621-626, 1998
Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene
R Meuwissen, SC Linn, M van der Valk, WJ Mooi, A Berns
Oncogene 20 (45), 6551-6558, 2001
Understanding the biology of triple-negative breast cancer
C Criscitiello, HA Azim Jr, PC Schouten, SC Linn, C Sotiriou
Annals of oncology 23, vi13-vi18, 2012
Validation of 70-gene prognosis signature in node-negative breast cancer
JM Bueno-de-Mesquita, SC Linn, R Keijzer, J Wesseling, DSA Nuyten, ...
Breast cancer research and treatment 117, 483-495, 2009
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