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Prasanthi Medarametla
Prasanthi Medarametla
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DPD-inspired discovery of novel LsrK kinase inhibitors: An opportunity to fight antimicrobial resistance
S Stotani, V Gatta, P Medarametla, M Padmanaban, A Karawajczyk, ...
Journal of Medicinal Chemistry 62 (5), 2720-2737, 2019
292019
Structure‐Based Virtual Screening of LsrK Kinase Inhibitors to Target Quorum Sensing
P Medarametla, V Gatta, T Kajander, T Laitinen, P Tammela, A Poso
ChemMedChem 13 (22), 2400-2407, 2018
212018
Assessing therapeutic potential of molecules: molecular property diagnostic suite for tuberculosis
AS Gaur, A Bhardwaj, A Sharma, L John, MR Vivek, N Tripathi, ...
Journal of Chemical Sciences 129, 515-531, 2017
212017
A QSAR and molecular modelling study towards new lead finding: polypharmacological approach to Mycobacterium tuberculosis
S Janardhan, L John, M Prasanthi, V Poroikov, G Narahari Sastry
SAR and QSAR in Environmental Research 28 (10), 815-832, 2017
202017
Structural and Functional Characterization of Malate Synthase G from Opportunistic Pathogen Pseudomonas aeruginosa
AC McVey, P Medarametla, X Chee, S Bartlett, A Poso, DR Spring, ...
Biochemistry 56 (41), 5539-5549, 2017
112017
Structural characterization of LsrK as a quorum sensing target and a comparison between X-ray and homology models
P Medarametla, T Kronenberger, T Laitinen, A Poso
Journal of Chemical Information and Modeling 61 (3), 1346-1353, 2021
72021
Molecular Modelling Approaches to Antibacterial Drug Design and Discovery
AK Agnieszka, M Prasanthi, B Damian, K Magdalena, M Dariusz, P Antti
Frontiers in Anti-Infective Drug Discovery 7, 153-222, 2018
32018
Cover Feature: Structure‐Based Virtual Screening of LsrK Kinase Inhibitors to Target Quorum Sensing (ChemMedChem 22/2018)
P Medarametla, V Gatta, T Kajander, T Laitinen, P Tammela, A Poso
ChemMedChem 13 (22), 2350-2350, 2018
12018
The helix-turn-helix motif in Pseudomonas aeruginosa ExsA monomer can recognize DNA and stabilize the putative ligand-binding domain
J Greenhalgh, P Medarametla, A Poso, M Welch, T Kronenberger, ...
2024
Identification and design of new antibacterial agents using computational approaches
P Medarametla
Itä-Suomen yliopisto, 2020
2020
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Artikelen 1–10