PINK1/PARKIN signalling in neurodegeneration and neuroinflammation PMJ Quinn, PI Moreira, AF Ambrósio, CH Alves Acta neuropathologica communications 8 (1), 1-20, 2020 | 221 | 2020 |
Targeted Ablation of Crb1 and Crb2 in Retinal Progenitor Cells Mimics Leber Congenital Amaurosis LP Pellissier, CH Alves, PM Quinn, RM Vos, N Tanimoto, DMS Lundvig, ... PLoS genetics 9 (12), e1003976, 2013 | 93 | 2013 |
Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene CH Alves, A Sanz Sanz, B Park, LP Pellissier, N Tanimoto, SC Beck, ... Human molecular genetics 22 (1), 35-50, 2013 | 93 | 2013 |
The CRB1 and adherens junction complex proteins in retinal development and maintenance CH Alves, LP Pellissier, J Wijnholds Progress in retinal and eye research 40, 35-52, 2014 | 87 | 2014 |
Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models LP Pellissier, PM Quinn, CH Alves, RM Vos, J Klooster, JG Flannery, ... Human molecular genetics 24 (11), 3104-3118, 2015 | 79 | 2015 |
Human iPSC-derived retinas recapitulate the fetal CRB1 CRB2 complex formation and demonstrate that photoreceptors and Müller glia are targets of AAV5 PM Quinn, TM Buck, AA Mulder, C Ohonin, CH Alves, RM Vos, M Bialecka, ... Stem Cell Reports 12 (5), 906-919, 2019 | 77 | 2019 |
Transthyretin is up-regulated by sex hormones in mice liver I Goncalves, CH Alves, T Quintela, G Baltazar, S Socorro, MJ Saraiva, ... Molecular and cellular biochemistry 317, 137-142, 2008 | 73 | 2008 |
Animal models of bone loss in inflammatory arthritis: from cytokines in the bench to novel treatments for bone loss in the bedside—a comprehensive review CH Alves, E Farrell, M Vis, EM Colin, E Lubberts Clinical reviews in allergy & immunology 51, 27-47, 2016 | 60 | 2016 |
Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa CH Alves, LP Pellissier, RM Vos, M Garcia Garrido, V Sothilingam, ... Human molecular genetics 23 (13), 3384-3401, 2014 | 60 | 2014 |
PALS1 is essential for retinal pigment epithelium structure and neural retina stratification B Park, CH Alves, DM Lundvig, N Tanimoto, SC Beck, G Huber, F Richard, ... Journal of Neuroscience 31 (47), 17230-17241, 2011 | 60 | 2011 |
17β-estradiol induces transthyretin expression in murine choroid plexus via an oestrogen receptor dependent pathway T Quintela, I Gonçalves, G Baltazar, CH Alves, MJ Saraiva, CRA Santos Cellular and molecular neurobiology 29, 475-483, 2009 | 56 | 2009 |
Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background CH Alves, K Bossers, RM Vos, AHW Essing, S Swagemakers, ... PLoS One 8 (12), e82532, 2013 | 47 | 2013 |
Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype PM Quinn, AA Mulder, C Henrique Alves, M Desrosiers, SI de Vries, ... Human Molecular Genetics 28 (1), 105-123, 2019 | 42 | 2019 |
CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function PM Quinn, CH Alves, J Klooster, J Wijnholds Human molecular genetics 27 (18), 3137-3153, 2018 | 42 | 2018 |
5α-dihydrotestosterone up-regulates transthyretin levels in mice and rat choroid plexus via an androgen receptor independent pathway T Quintela, CH Alves, I Goncalves, G Baltazar, MJ Saraiva, CRA Santos Brain research 1229, 18-26, 2008 | 42 | 2008 |
Microglia contribution to the regulation of the retinal and choroidal vasculature in age-related macular degeneration CH Alves, R Fernandes, AR Santiago, AF Ambrosio Cells 9 (5), 1217, 2020 | 39 | 2020 |
Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon JJ Dudok, M Murtaza, CH Alves, P Rashbass, J Wijnholds Neuroscience research 108, 12-23, 2016 | 30 | 2016 |
Progesterone enhances transthyretin expression in the rat choroid plexus in vitro and in vivo via progesterone receptor T Quintela, I Gonçalves, A Martinho, CH Alves, MJ Saraiva, P Rocha, ... Journal of Molecular Neuroscience 44, 152-158, 2011 | 29 | 2011 |
Androgen receptor is expressed in murine choroid plexus and downregulated by 5α-dihydrotestosterone in male and female mice CH Alves, I Gonçalves, S Socorro, G Baltazar, T Quintela, CRA Santos Journal of molecular neuroscience 38, 41-49, 2009 | 27 | 2009 |
CRB2 loss in rod photoreceptors is associated with progressive loss of retinal contrast sensitivity CH Alves, N Boon, AA Mulder, AJ Koster, CR Jost, J Wijnholds International Journal of Molecular Sciences 20 (17), 4069, 2019 | 26 | 2019 |