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Manuel alcalde rico
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Bacterial multidrug efflux pumps: much more than antibiotic resistance determinants
P Blanco, S Hernando-Amado, JA Reales-Calderon, F Corona, F Lira, ...
Microorganisms 4 (1), 14, 2016
6912016
Multidrug efflux pumps at the crossroad between antibiotic resistance and bacterial virulence
M Alcalde-Rico, S Hernando-Amado, P Blanco, JL Martínez
Frontiers in microbiology 7, 215898, 2016
2382016
Multidrug efflux pumps as main players in intrinsic and acquired resistance to antimicrobials
S Hernando-Amado, P Blanco, M Alcalde-Rico, F Corona, ...
Drug Resistance Updates 28, 13-27, 2016
1842016
Metabolic Compensation of Fitness Costs Is a General Outcome for Antibiotic-Resistant Pseudomonas aeruginosa Mutants Overexpressing Efflux Pumps
J Olivares Pacheco, C Alvarez-Ortega, M Alcalde Rico, JL Martínez
MBio 8 (4), 10.1128/mbio. 00500-17, 2017
852017
Role of the multidrug resistance efflux pump MexCD-OprJ in the Pseudomonas aeruginosa quorum sensing response
M Alcalde-Rico, J Olivares-Pacheco, C Alvarez-Ortega, M Cámara, ...
Frontiers in Microbiology 9, 415014, 2018
712018
The development of efflux pump inhibitors to treat Gram-negative infections
P Blanco, F Sanz-García, S Hernando-Amado, JL Martínez, ...
Expert opinion on drug discovery 13 (10), 919-931, 2018
472018
Naringenin inhibition of the Pseudomonas aeruginosa quorum sensing response is based on its time-dependent competition with N-(3-Oxo-dodecanoyl)-L-homoserine lactone for LasR …
S Hernando-Amado, M Alcalde-Rico, T Gil-Gil, JR Valverde, JL Martínez
Frontiers in molecular biosciences 7, 25, 2020
462020
The impaired quorum sensing response of Pseudomonas aeruginosa MexAB‐OprM efflux pump overexpressing mutants is not due to non‐physiological efflux of 3 …
M Alcalde‐Rico, J Olivares‐Pacheco, N Halliday, M Cámara, JL Martínez
Environmental Microbiology 22 (12), 5167-5188, 2020
302020
Novel Inducers of the Expression of Multidrug Efflux Pumps That Trigger Pseudomonas aeruginosa Transient Antibiotic Resistance
P Laborda, M Alcalde-Rico, P Blanco, JL Martínez, S Hernando-Amado
Antimicrobial Agents and Chemotherapy 63 (11), 10.1128/aac. 01095-19, 2019
242019
The analysis of the antibiotic resistome offers new opportunities for therapeutic intervention
F Corona, P Blanco, M Alcalde-Rico, S Hernando-Amado, F Lira, ...
Future medicinal chemistry 8 (10), 1133-1151, 2016
192016
Discovery of inhibitors of Pseudomonas aeruginosa virulence through the search for natural‐like compounds with a dual role as inducers and substrates of efflux …
P Laborda, M Alcalde‐Rico, A Chini, JL Martínez, S Hernando‐Amado
Environmental Microbiology 23 (12), 7396-7411, 2021
162021
Genetic characterization of clinically relevant class 1 integrons carried by multidrug resistant bacteria (MDRB) isolated from the gut microbiota of highly antibiotic treated …
F Vásquez-Ponce, S Higuera-Llantén, J Parás-Silva, N Gamboa-Acuña, ...
Journal of Global Antimicrobial Resistance 29, 55-62, 2022
82022
The MexJK Multidrug Efflux Pump Is Not Involved in Acquired or Intrinsic Antibiotic Resistance in Pseudomonas aeruginosa, but Modulates the Bacterial Quorum …
R Amieva, T Gil-Gil, JL Martínez, M Alcalde-Rico
International Journal of Molecular Sciences 23 (14), 7492, 2022
72022
Methods for measuring the production of quorum sensing signal molecules
M Alcalde-Rico, JL Martínez
Antibiotic Resistance Protocols, 1-15, 2018
62018
Use of phenotype microarrays to study the effect of acquisition of resistance to antimicrobials in bacterial physiology
JA Reales-Calderon, P Blanco, M Alcalde-Rico, F Corona, F Lira, ...
Research in microbiology 167 (9-10), 723-730, 2016
52016
Acquisition of resistance to ceftazidime-avibactam during infection treatment in Pseudomonas aeruginosa through D179Y mutation in one of two blaKPC-2 gene …
P García, B Brito, M Alcalde-Rico, JM Munita, JRW Martínez, ...
Frontiers in Cellular and Infection Microbiology 12, 981792, 2022
32022
Role of the multi-drug efflux systems on the baseline susceptibility to ceftazidime/avibactam and ceftolozane/tazobactam in clinical isolates of non-carbapenemase-producing …
MJ Contreras-Gómez, JRW Martinez, L Rivas, R Riquelme-Neira, ...
Frontiers in Pharmacology 13, 1007162, 2022
22022
Real-world performance of susceptibility testing for ceftolozane/tazobactam against non-carbapenemase-producing carbapenem-resistant Pseudomonas aeruginosa
L Rivas, M Alcalde-Rico, JRW Martínez, MV Moreno, P Rojas, A Wozniak, ...
Antimicrobial Agents and Chemotherapy 66 (1), e01657-21, 2022
22022
Primer aislado de Pseudomonas aeruginosa productora de Sao Paulo metalo-β-lactamasa (SPM-1) en un paciente chileno
A Wozniak, N Rodríguez, M Alcalde-Rico, C Castillo, P García
Revista chilena de infectología 38 (5), 724-726, 2021
22021
Dynamics of the MRSA Population in a Chilean Hospital: a Phylogenomic Analysis (2000–2016)
JRW Martínez, PJ Planet, M Spencer-Sandino, L Rivas, L Díaz, ...
Microbiology Spectrum 11 (4), e05351-22, 2023
12023
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