| Prediction and validation of the distinct dynamics of transient and sustained ERK activation S Sasagawa, Y Ozaki, K Fujita, S Kuroda Nature Cell Biology 7 (4), 365-373, 2005 | 545 | 2005 |
| Integrating pathways of Parkinson's disease in a molecular interaction map KA Fujita, M Ostaszewski, Y Matsuoka, S Ghosh, E Glaab, C Trefois, ... Molecular Neurobiology 49 (1), 88-102, 2014 | 265 | 2014 |
| Decoupling of receptor and downstream signals in the akt pathway by its low-pass filter characteristics KA Fujita, Y Toyoshima, S Uda, Y Ozaki, H Kubota, S Kuroda Science Signaling 3 (132), ra56, 2010 | 100 | 2010 |
| Sensitivity control through attenuation of signal transfer efficiency by negative regulation of cellular signalling. Y Toyoshima, H Kakuda, KA Fujita, S Uda, S Kuroda Nature Communications 3, 743-743, 2012 | 26 | 2012 |
| Deep learning generates custom-made logistic regression models for explaining how breast cancer subtypes are classified T Shibahara, C Wada, Y Yamashita, K Fujita, M Sato, J Kuwata, ... Plos one 18 (5), e0286072, 2023 | 6 | 2023 |
| A mechanism-based simulation model of hepatic toxicity to predict cell death dynamics through mitochondrial dysfunction upon long-term exposure to drug KA Fujita, A Crudu, A Riu, G Ouedraogo, S Teissier, S Miyabe, I Suzuki, ... The Journal of Toxicological Sciences 42 (Supplement), S293, 2017 | | 2017 |
| A MECHANISM-BASED SIMULATION MODEL OF HEPATIC TOXICITY TO PREDICT CELL DEATH DYNAMICS THROUGH MITOCHONDRIAL DYSFUNCTION UPON LONG-TERM EXPOSURE TO DRUG A Riu, A Crudu, KA Fujita, G Ouedraogo, S Teissier, S Miyabe, I Suzuki, ... The 10th Congress on Alternatives and Animal Use in the Life Sciences, 2017 | | 2017 |
| A mechanism-based hepatotoxicity simulation model to capture dose-dependent cell death dynamics in response to the drugs amiodarone and valproate A Crudu, R Note, A Riu, G Ouedraogo, O Perin, S Jager, C Gomes, ... The Society of Toxicology 55th Annual Meeting and ToxExpo, 2016 | | 2016 |
| Weaving Knowledge into Biological Pathways in a Collaborative Manner Y Matsuoka, K Fujita, S Ghosh, H Kitano Computational Systems Toxicology, 181-208, 2015 | | 2015 |
| Curation of complex molecular pathways of Parkinson's disease as a collaborative scientific community effort S Gebel, M Ostaszewski, P Gawron, PMA Antony, C Trefois, KA Fujita, ... Movement Disorders 29, S11-S12, 2014 | | 2014 |
| Ageing neuron, clean up your room! KA Fujita http://minerva.uni.lu/pd_map/index.php/blog-menu/29-ageing-neuron-clean-up, 2014 | | 2014 |
| EGFR inhibitor can serve as a downstream activator in Akt pathway by its low-pass filter characteristics (Japanese title: Akt経路のローパスフィルタ特性によって, EGFR阻害剤が下流の活 … KA Fujita, Y Toyoshima, S Kuroda 実験医学 29 (1), 65-69, 2011 | | 2011 |
| Frequency Response Analysis of Signal Transduction (Japanese title: 周波数応答を応用したAktシグナル伝達経路のダイナミクスの解析) KA Fujita, Y Toyoshima, S Kuroda 細胞工学 29 (4), 349-354, 2010 | | 2010 |
| 3TP1-02 Akt 経路のローパスフィルタ特性による EGF 受容体と下流のリン酸化シグナル強度の逆転 (数理生物学, 第 47 回日本生物物理学会年会) T Yu, F Kazuhiro, U Shinsuke, O Yu-ichi, K Hiroyuki, K Shinya 生物物理 49 (supplement), S59, 2009 | | 2009 |
| System understanding of ERK signal network: mechanisms for detecting temporal rate and final concentration of growth factors S Sasagawa, Y Ozaki, K Fujita, S Kuroda Protein, nucleic acid and enzyme 50 (16 Suppl), 2275-2281, 2005 | | 2005 |
Samik GhoshSenior Scientist, The Systems Biology Institute, TokyoVerified email at sbi.jp
