| EFNS guidelines on the clinical management of amyotrophic lateral sclerosis (MALS)–revised report of an EFNS task force EFNS Task Force on Diagnosis and Management of Amyotrophic Lateral Sclerosis: European journal of neurology 19 (3), 360-375, 2012 | 1137 | 2012 |
| Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility International Multiple Sclerosis Genetics Consortium*†, ANZgene, ... Science 365 (6460), eaav7188, 2019 | 963 | 2019 |
| Amyotrophic lateral sclerosis: a clinical review P Masrori, P Van Damme European journal of neurology 27 (10), 1918-1929, 2020 | 841 | 2020 |
| Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS E Storkebaum, D Lambrechts, M Dewerchin, MP Moreno-Murciano, ... Nature neuroscience 8 (1), 85-92, 2005 | 627 | 2005 |
| Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1267-1288, 2018 | 626 | 2018 |
| Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind … JF Howard, K Utsugisawa, M Benatar, H Murai, RJ Barohn, I Illa, S Jacob, ... The Lancet Neurology 16 (12), 976-986, 2017 | 621 | 2017 |
| Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ... Nature genetics 48 (9), 1043-1048, 2016 | 614 | 2016 |
| The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis L Van Den Bosch, P Van Damme, E Bogaert, W Robberecht Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (11-12 …, 2006 | 609 | 2006 |
| Gain of toxicity from ALS/FTD-linked repeat expansions in C9ORF72 is alleviated by antisense oligonucleotides targeting GGGGCC-containing RNAs J Jiang, Q Zhu, TF Gendron, S Saberi, M McAlonis-Downes, A Seelman, ... Neuron 90 (3), 535-550, 2016 | 586 | 2016 |
| HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease C d'Ydewalle, J Krishnan, DM Chiheb, P Van Damme, J Irobi, ... Nature medicine 17 (8), 968-974, 2011 | 567 | 2011 |
| Phase separation of C9orf72 dipeptide repeats perturbs stress granule dynamics S Boeynaems, E Bogaert, D Kovacs, A Konijnenberg, E Timmerman, ... Molecular cell 65 (6), 1044-1055. e5, 2017 | 521 | 2017 |
| Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS T Miller, M Cudkowicz, PJ Shaw, PM Andersen, N Atassi, RC Bucelli, ... New England Journal of Medicine 383 (2), 109-119, 2020 | 486 | 2020 |
| Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival P Van Damme, A Van Hoecke, D Lambrechts, P Vanacker, E Bogaert, ... The Journal of cell biology 181 (1), 37-41, 2008 | 469 | 2008 |
| Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model HJ Westeneng, TPA Debray, AE Visser, RPA van Eijk, JPK Rooney, ... The Lancet Neurology 17 (5), 423-433, 2018 | 465 | 2018 |
| Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS TM Miller, ME Cudkowicz, A Genge, PJ Shaw, G Sobue, RC Bucelli, ... New England Journal of Medicine 387 (12), 1099-1110, 2022 | 415 | 2022 |
| HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients W Guo, M Naujock, L Fumagalli, T Vandoorne, P Baatsen, R Boon, ... Nature communications 8 (1), 861, 2017 | 362 | 2017 |
| EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans A Van Hoecke, L Schoonaert, R Lemmens, M Timmers, KA Staats, ... Nature medicine 18 (9), 1418-1422, 2012 | 355 | 2012 |
| Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology W Van Rheenen, RAA Van Der Spek, MK Bakker, JJFA Van Vugt, PJ Hop, ... Nature genetics 53 (12), 1636-1648, 2021 | 334 | 2021 |
| Regional variation of Guillain-Barré syndrome AY Doets, C Verboon, B Van Den Berg, T Harbo, DR Cornblath, ... Brain 141 (10), 2866-2877, 2018 | 327 | 2018 |
| NEK1 variants confer susceptibility to amyotrophic lateral sclerosis KP Kenna, PTC Van Doormaal, AM Dekker, N Ticozzi, BJ Kenna, ... Nature genetics 48 (9), 1037-1042, 2016 | 305 | 2016 |
Ludo Van Den BoschKU Leuven & VIBVerified email at kuleuven.vib.be
