Vascularized and functional human liver from an iPSC-derived organ bud transplant T Takebe, K Sekine, M Enomura, H Koike, M Kimura, T Ogaeri, RR Zhang, ... Nature 499 (7459), 481-484, 2013 | 2235 | 2013 |
Multilineage communication regulates human liver bud development from pluripotency JG Camp, K Sekine, T Gerber, H Loeffler-Wirth, H Binder, M Gac, ... Nature 546 (7659), 533-538, 2017 | 510 | 2017 |
Vascularized and complex organ buds from diverse tissues via mesenchymal cell-driven condensation T Takebe, M Enomura, E Yoshizawa, M Kimura, H Koike, Y Ueno, ... Cell stem cell 16 (5), 556-565, 2015 | 471 | 2015 |
Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant T Takebe, RR Zhang, H Koike, M Kimura, E Yoshizawa, M Enomura, ... Nature protocols 9 (2), 396-409, 2014 | 415 | 2014 |
Modeling steatohepatitis in humans with pluripotent stem cell-derived organoids R Ouchi, S Togo, M Kimura, T Shinozawa, M Koido, H Koike, ... Cell metabolism 30 (2), 374-384. e6, 2019 | 376 | 2019 |
Massive and reproducible production of liver buds entirely from human pluripotent stem cells T Takebe, K Sekine, M Kimura, E Yoshizawa, S Ayano, M Koido, ... Cell reports 21 (10), 2661-2670, 2017 | 334 | 2017 |
Organoids by design T Takebe, JM Wells Science 364 (6444), 956-959, 2019 | 307 | 2019 |
Modelling human hepato-biliary-pancreatic organogenesis from the foregut–midgut boundary H Koike, K Iwasawa, R Ouchi, M Maezawa, K Giesbrecht, N Saiki, ... Nature 574 (7776), 112-116, 2019 | 252 | 2019 |
Synergistic engineering: organoids meet organs-on-a-chip T Takebe, B Zhang, M Radisic Cell stem cell 21 (3), 297-300, 2017 | 239 | 2017 |
High-fidelity drug-induced liver injury screen using human pluripotent stem cell–derived organoids T Shinozawa, M Kimura, Y Cai, N Saiki, Y Yoneyama, R Ouchi, H Koike, ... Gastroenterology 160 (3), 831-846. e10, 2021 | 197 | 2021 |
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids A Marsee, FJM Roos, MMA Verstegen, F Roos, M Verstegen, H Clevers, ... Cell Stem Cell 28 (5), 816-832, 2021 | 168 | 2021 |
Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells A Asai, E Aihara, C Watson, R Mourya, T Mizuochi, P Shivakumar, ... Development 144 (6), 1056-1064, 2017 | 162 | 2017 |
Recapitulation of hepatitis B virus–host interactions in liver organoids from human induced pluripotent stem cells YZ Nie, YW Zheng, K Miyakawa, S Murata, RR Zhang, K Sekine, Y Ueno, ... EBioMedicine 35, 114-123, 2018 | 148 | 2018 |
Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis L Han, P Chaturvedi, K Kishimoto, H Koike, T Nasr, K Iwasawa, ... Nature communications 11 (1), 4158, 2020 | 140 | 2020 |
Self-condensation culture enables vascularization of tissue fragments for efficient therapeutic transplantation Y Takahashi, K Sekine, T Kin, T Takebe, H Taniguchi Cell reports 23 (6), 1620-1629, 2018 | 118 | 2018 |
Reconstruction of human elastic cartilage by a CD44+ CD90+ stem cell in the ear perichondrium S Kobayashi, T Takebe, M Inui, S Iwai, H Kan, YW Zheng, J Maegawa, ... Proceedings of the National Academy of Sciences 108 (35), 14479-14484, 2011 | 104 | 2011 |
Human iPSC-derived posterior gut progenitors are expandable and capable of forming gut and liver organoids RR Zhang, M Koido, T Tadokoro, R Ouchi, T Matsuno, Y Ueno, K Sekine, ... Stem Cell Reports 10 (3), 780-793, 2018 | 78 | 2018 |
Simultaneous Zn2+ tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells H Fang, S Geng, M Hao, Q Chen, M Liu, C Liu, Z Tian, C Wang, T Takebe, ... Nature Communications 12 (1), 109, 2021 | 75 | 2021 |
Polygenic architecture informs potential vulnerability to drug-induced liver injury M Koido, E Kawakami, J Fukumura, Y Noguchi, M Ohori, Y Nio, P Nicoletti, ... Nature medicine 26 (10), 1541-1548, 2020 | 69 | 2020 |
De Novo-Designed Near-Infrared Nanoaggregates for Super-Resolution Monitoring of Lysosomes in Cells, in Whole Organoids, and in Vivo H Fang, S Yao, Q Chen, C Liu, Y Cai, S Geng, Y Bai, Z Tian, AL Zacharias, ... ACS nano 13 (12), 14426-14436, 2019 | 63 | 2019 |