Gerry Nicolaes
Gerry Nicolaes
Associate Professor of Biochemistry - Maastricht University
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Oral contraceptives and venous thrombosis: different sensitivities to activated protein C in women using second‐and third‐generation oral contraceptives
J Rosing, G Tans, GAF Nicolaes, M Thomassen, R Van Oerle, ...
British journal of haematology 97 (1), 233-238, 1997
Low-dose oral contraceptives and acquired resistance to activated protein C: a randomised cross-over study
J Rosing, S Middeldorp, J Curvers, MCL GDlig, GAF Nicolaes, ...
The Lancet 354 (9195), 2036-2040, 1999
Peptide bond cleavages and loss of functional activity during inactivation of factor Va and factor VaR506Q by activated protein C
GAF Nicolaes, G Tans, MCLGD Thomassen, HC Hemker, I Pabinger, ...
Journal of Biological Chemistry 270 (36), 21158-21166, 1995
Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C
J Rosing, L Hoekema, GAF Nicolaes, MCLGD Thomassen, HC Hemker, ...
Journal of Biological Chemistry 270 (46), 27852-27858, 1995
Factor V and thrombotic disease: description of a janus-faced protein
GAF Nicolaes, B Dahlbäck
Arteriosclerosis, thrombosis, and vascular biology 22 (4), 530-538, 2002
Coagulation factor V and thrombophilia: background and mechanisms
K Segers, B Dahlback, GAF Nicolaes
Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis
KCAA Wildhagen, P García de Frutos, CP Reutelingsperger, R Schrijver, ...
Blood, The Journal of the American Society of Hematology 123 (7), 1098-1101, 2014
Riboflavin-responsive oxidative phosphorylation complex I deficiency caused by defective ACAD9: new function for an old gene
M Gerards, BJC Van Den Bosch, K Danhauser, V Serre, M van Weeghel, ...
Brain 134 (1), 210-219, 2011
Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance
A Chatzigeorgiou, T Seijkens, B Zarzycka, D Engel, M Poggi, ...
Proceedings of the National Academy of Sciences 111 (7), 2686-2691, 2014
Impaired APC cofactor activity of factor V plays a major role in the APC resistance associated with the factor V Leiden (R506Q) and R2 (H1299R) mutations
E Castoldi, JM Brugge, GAF Nicolaes, D Girelli, G Tans, J Rosing
Blood 103 (11), 4173-4179, 2004
Effect of activated protein C on thrombin generation and on the thrombin potential in plasma of normal and APC-resistant individuals.
GA Nicolaes, MC Thomassen, G Tans, J Rosing, HC Hemker
Blood coagulation & fibrinolysis: an international journal in haemostasis …, 1997
Acquired APC resistance and oral contraceptives: differences between two functional tests
J Curvers, MCLGD Thomassen, GAF Nicolaes, R Van Oerle, K Hamulyak, ...
British journal of haematology 105 (1), 88-94, 1999
Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death
C Silvestre-Roig, Q Braster, K Wichapong, EY Lee, JM Teulon, ...
Nature 569 (7755), 236-240, 2019
Comparative analysis of pharmacophore screening tools
MPA Sanders, AJM Barbosa, B Zarzycka, GAF Nicolaes, JPG Klomp, ...
Journal of chemical information and modeling 52 (6), 1607-1620, 2012
Re-evaluation of the role of the protein S-C4b binding protein complex in activated protein C-catalyzed factor Va-inactivation
LFA Maurissen, MCLGD Thomassen, GAF Nicolaes, B Dahlbäck, G Tans, ...
Blood, The Journal of the American Society of Hematology 111 (6), 3034-3041, 2008
Factor Xa activation of factor V is of paramount importance in initiating the coagulation system: lessons from a tick salivary protein
TJ Schuijt, K Bakhtiari, S Daffre, K DePonte, SJH Wielders, JA Marquart, ...
Circulation 128 (3), 254-266, 2013
Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation
P Von Hundelshausen, SM Agten, V Eckardt, X Blanchet, MM Schmitt, ...
Science translational medicine 9 (384), 2017
Partial glycosylation of Asn2181 in human factor V as a cause of molecular and functional heterogeneity. Modulation of glycosylation efficiency by mutagenesis of the consensus …
GAF Nicolaes, BO Villoutreix, B Dahlbäck
Biochemistry 38 (41), 13584-13591, 1999
Inhibiting inflammation with myeloid cell-specific nanobiologics promotes organ transplant acceptance
MS Braza, MMT van Leent, M Lameijer, BL Sanchez-Gaytan, RJW Arts, ...
Immunity 49 (5), 819-828. e6, 2018
Targeting CD40-induced TRAF6 signaling in macrophages reduces atherosclerosis
TTP Seijkens, CM van Tiel, PJH Kusters, D Atzler, O Soehnlein, ...
Journal of the American College of Cardiology 71 (5), 527-542, 2018
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