Oral contraceptives and venous thrombosis: different sensitivities to activated protein C in women using second‐and third‐generation oral contraceptives J Rosing, G Tans, GAF Nicolaes, M Thomassen, R Van Oerle, ... British journal of haematology 97 (1), 233-238, 1997 | 428 | 1997 |
Low-dose oral contraceptives and acquired resistance to activated protein C: a randomised cross-over study J Rosing, S Middeldorp, J Curvers, MCL GDlig, GAF Nicolaes, ... The Lancet 354 (9195), 2036-2040, 1999 | 319 | 1999 |
Peptide bond cleavages and loss of functional activity during inactivation of factor Va and factor VaR506Q by activated protein C GAF Nicolaes, G Tans, MCLGD Thomassen, HC Hemker, I Pabinger, ... Journal of Biological Chemistry 270 (36), 21158-21166, 1995 | 288 | 1995 |
Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C J Rosing, L Hoekema, GAF Nicolaes, MCLGD Thomassen, HC Hemker, ... Journal of Biological Chemistry 270 (46), 27852-27858, 1995 | 278 | 1995 |
Factor V and thrombotic disease: description of a janus-faced protein GAF Nicolaes, B Dahlbäck Arteriosclerosis, thrombosis, and vascular biology 22 (4), 530-538, 2002 | 260 | 2002 |
Coagulation factor V and thrombophilia: background and mechanisms K Segers, B Dahlback, GAF Nicolaes THROMBOSIS AND HAEMOSTASIS-STUTTGART- 98 (3), 530, 2007 | 209 | 2007 |
Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis KCAA Wildhagen, P García de Frutos, CP Reutelingsperger, R Schrijver, ... Blood, The Journal of the American Society of Hematology 123 (7), 1098-1101, 2014 | 196 | 2014 |
Riboflavin-responsive oxidative phosphorylation complex I deficiency caused by defective ACAD9: new function for an old gene M Gerards, BJC Van Den Bosch, K Danhauser, V Serre, M van Weeghel, ... Brain 134 (1), 210-219, 2011 | 120 | 2011 |
Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance A Chatzigeorgiou, T Seijkens, B Zarzycka, D Engel, M Poggi, ... Proceedings of the National Academy of Sciences 111 (7), 2686-2691, 2014 | 118 | 2014 |
Impaired APC cofactor activity of factor V plays a major role in the APC resistance associated with the factor V Leiden (R506Q) and R2 (H1299R) mutations E Castoldi, JM Brugge, GAF Nicolaes, D Girelli, G Tans, J Rosing Blood 103 (11), 4173-4179, 2004 | 114 | 2004 |
Effect of activated protein C on thrombin generation and on the thrombin potential in plasma of normal and APC-resistant individuals. GA Nicolaes, MC Thomassen, G Tans, J Rosing, HC Hemker Blood coagulation & fibrinolysis: an international journal in haemostasis …, 1997 | 108 | 1997 |
Acquired APC resistance and oral contraceptives: differences between two functional tests J Curvers, MCLGD Thomassen, GAF Nicolaes, R Van Oerle, K Hamulyak, ... British journal of haematology 105 (1), 88-94, 1999 | 92 | 1999 |
Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death C Silvestre-Roig, Q Braster, K Wichapong, EY Lee, JM Teulon, ... Nature 569 (7755), 236-240, 2019 | 89 | 2019 |
Comparative analysis of pharmacophore screening tools MPA Sanders, AJM Barbosa, B Zarzycka, GAF Nicolaes, JPG Klomp, ... Journal of chemical information and modeling 52 (6), 1607-1620, 2012 | 83 | 2012 |
Re-evaluation of the role of the protein S-C4b binding protein complex in activated protein C-catalyzed factor Va-inactivation LFA Maurissen, MCLGD Thomassen, GAF Nicolaes, B Dahlbäck, G Tans, ... Blood, The Journal of the American Society of Hematology 111 (6), 3034-3041, 2008 | 78 | 2008 |
Factor Xa activation of factor V is of paramount importance in initiating the coagulation system: lessons from a tick salivary protein TJ Schuijt, K Bakhtiari, S Daffre, K DePonte, SJH Wielders, JA Marquart, ... Circulation 128 (3), 254-266, 2013 | 77 | 2013 |
Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation P Von Hundelshausen, SM Agten, V Eckardt, X Blanchet, MM Schmitt, ... Science translational medicine 9 (384), 2017 | 75 | 2017 |
Partial glycosylation of Asn2181 in human factor V as a cause of molecular and functional heterogeneity. Modulation of glycosylation efficiency by mutagenesis of the consensus … GAF Nicolaes, BO Villoutreix, B Dahlbäck Biochemistry 38 (41), 13584-13591, 1999 | 75 | 1999 |
Inhibiting inflammation with myeloid cell-specific nanobiologics promotes organ transplant acceptance MS Braza, MMT van Leent, M Lameijer, BL Sanchez-Gaytan, RJW Arts, ... Immunity 49 (5), 819-828. e6, 2018 | 73 | 2018 |
Targeting CD40-induced TRAF6 signaling in macrophages reduces atherosclerosis TTP Seijkens, CM van Tiel, PJH Kusters, D Atzler, O Soehnlein, ... Journal of the American College of Cardiology 71 (5), 527-542, 2018 | 71 | 2018 |