| Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells JJ Hulce, AB Cognetta, MJ Niphakis, SE Tully, BF Cravatt Nature methods 10 (3), 259-264, 2013 | 429 | 2013 |
| Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474 ACM van Esbroeck, APA Janssen, AB Cognetta III, D Ogasawara, ... Science 356 (6342), 1084-1087, 2017 | 313 | 2017 |
| A global map of lipid-binding proteins and their ligandability in cells MJ Niphakis, KM Lum, AB Cognetta, BE Correia, TA Ichu, J Olucha, ... Cell 161 (7), 1668-1680, 2015 | 213 | 2015 |
| Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates JW Chang, MJ Niphakis, KM Lum, AB Cognetta, C Wang, ML Matthews, ... Chemistry & biology 19 (5), 579-588, 2012 | 212 | 2012 |
| Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium N Pentinmikko, S Iqbal, M Mana, S Andersson, AB Cognetta III, RM Suciu, ... Nature 571 (7765), 398-402, 2019 | 195 | 2019 |
| Evaluation of NHS carbamates as a potent and selective class of endocannabinoid hydrolase inhibitors MJ Niphakis, AB Cognetta III, JW Chang, MW Buczynski, LH Parsons, ... ACS chemical neuroscience 4 (9), 1322-1332, 2013 | 149 | 2013 |
| Proteome-wide reactivity profiling identifies diverse carbamate chemotypes tuned for serine hydrolase inhibition JW Chang, AB Cognetta III, MJ Niphakis, BF Cravatt ACS chemical biology 8 (7), 1590-1599, 2013 | 125 | 2013 |
| AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs WH Parsons, MJ Kolar, SS Kamat, ABC III, JJ Hulce, E Saez, BB Kahn, ... Nature chemical biology 12 (5), 367-372, 2016 | 78 | 2016 |
| Selective N-hydroxyhydantoin carbamate inhibitors of mammalian serine hydrolases AB Cognetta, MJ Niphakis, HC Lee, ML Martini, JJ Hulce, BF Cravatt Chemistry & biology 22 (7), 928-937, 2015 | 62 | 2015 |
| In vivo quantification of formulated and chemically modified small interfering RNA by heating-in-Triton quantitative reverse transcription polymerase chain reaction … Y Landesman, N Svrzikapa, A Cognetta, X Zhang, BR Bettencourt, ... Silence 1, 1-14, 2010 | 56 | 2010 |
| Multicomponent mapping of boron chemotypes furnishes selective enzyme inhibitors J Tan, AB Cognetta III, DB Diaz, KM Lum, S Adachi, S Kundu, BF Cravatt, ... Nature communications 8 (1), 1760, 2017 | 47 | 2017 |
| Global portrait of protein targets of metabolites of the neurotoxic compound BIA 10–2474 Z Huang, D Ogasawara, UI Seneviratne, AB Cognetta III, CW Am Ende, ... ACS chemical biology 14 (2), 192-197, 2019 | 46 | 2019 |
| Selective irreversible inhibitors of the Wnt-deacylating enzyme NOTUM developed by activity-based protein profiling RM Suciu, AB Cognetta III, ZE Potter, BF Cravatt ACS medicinal chemistry letters 9 (6), 563-568, 2018 | 44 | 2018 |
| Remodeling natural products: chemistry and serine hydrolase activity of a rocaglate-derived β-lactone NJ Lajkiewicz, AB Cognetta III, MJ Niphakis, BF Cravatt, JA Porco Jr Journal of the American Chemical Society 136 (6), 2659-2664, 2014 | 43 | 2014 |
| Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan AL Chen, KM Lum, P Lara-Gonzalez, D Ogasawara, AB Cognetta III, A To, ... Nature chemical biology 15 (5), 453-462, 2019 | 40 | 2019 |
| Facile synthesis of borofragments and their evaluation in activity-based protein profiling S Adachi, AB Cognetta, MJ Niphakis, Z He, A Zajdlik, JDS Denis, ... Chemical communications 51 (17), 3608-3611, 2015 | 34 | 2015 |
| Design of benzoxathiazin-3-one 1, 1-dioxides as a new class of irreversible serine hydrolase inhibitors: discovery of a uniquely selective PNPLA4 inhibitor AF Kornahrens, AB Cognetta III, DM Brody, ML Matthews, BF Cravatt, ... Journal of the American Chemical Society 139 (20), 7052-7061, 2017 | 30 | 2017 |
| A screen for protein–protein interactions in live mycobacteria reveals a functional link between the virulence-associated lipid transporter LprG and the mycolyltransferase … MH Touchette, ER Van Vlack, L Bai, J Kim, AB Cognetta III, ML Previti, ... ACS infectious diseases 3 (5), 336-348, 2017 | 27 | 2017 |
| Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling M Li, HV Patel, AB Cognetta, TC Smith, I Mallick, JF Cavalier, ML Previti, ... Cell chemical biology 29 (5), 883-896. e5, 2022 | 24 | 2022 |
| Lipid probes and uses thereof BF Cravatt, MJ Niphakis, K Lum, B Correia, A Cognetta, J Hulce US Patent 10,168,342, 2019 | 6 | 2019 |
