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Jan Ehses
Jan Ehses
Assistant Professor, University of British Columbia
Verified email at mail.ubc.ca - Homepage
Title
Cited by
Cited by
Year
Interleukin-1–receptor antagonist in type 2 diabetes mellitus
CM Larsen, M Faulenbach, A Vaag, A Vølund, JA Ehses, B Seifert, ...
New England Journal of Medicine 356 (15), 1517-1526, 2007
21422007
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
H Ellingsgaard, I Hauselmann, B Schuler, AM Habib, LL Baggio, DT Meier, ...
Nature medicine 17 (11), 1481-1489, 2011
9792011
Increased number of islet-associated macrophages in type 2 diabetes
JA Ehses, A Perren, E Eppler, P Ribaux, JA Pospisilik, R Maor-Cahn, ...
Diabetes 56 (9), 2356-2370, 2007
8992007
Mechanisms of β-cell death in type 2 diabetes
MY Donath, JA Ehses, K Maedler, DM Schumann, H Ellingsgaard, ...
Diabetes 54 (suppl_2), S108-S113, 2005
6122005
Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes
CM Larsen, M Faulenbach, A Vaag, JA Ehses, MY Donath, ...
Diabetes care 32 (9), 1663-1668, 2009
4782009
Dipeptidyl peptidase IV inhibitor treatment stimulates β-cell survival and islet neogenesis in streptozotocin-induced diabetic rats
JA Pospisilik, J Martin, T Doty, JA Ehses, N Pamir, FC Lynn, S Piteau, ...
Diabetes 52 (3), 741-750, 2003
4752003
Islet inflammation impairs the pancreatic β-cell in type 2 diabetes
MY Donath, M Böni-Schnetzler, H Ellingsgaard, JA Ehses
Physiology 24 (6), 325-331, 2009
4412009
Islet inflammation in type 2 diabetes: from metabolic stress to therapy
MY Donath, DM Schumann, M Faulenbach, H Ellingsgaard, A Perren, ...
Diabetes care 31 (Supplement_2), S161-S164, 2008
4332008
IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat
JA Ehses, G Lacraz, MH Giroix, F Schmidlin, J Coulaud, N Kassis, ...
Proceedings of the National Academy of Sciences 106 (33), 13998-14003, 2009
4222009
Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I
M Böni-Schnetzler, S Boller, S Debray, K Bouzakri, DT Meier, R Prazak, ...
Endocrinology 150 (12), 5218-5229, 2009
4082009
Increased interleukin (IL)-1β messenger ribonucleic acid expression in β-cells of individuals with type 2 diabetes and regulation of IL-1β in human islets by glucose and …
M Böni-Schnetzler, J Thorne, G Parnaud, L Marselli, JA Ehses, ...
The Journal of Clinical Endocrinology & Metabolism 93 (10), 4065-4074, 2008
4072008
Leptin modulates β cell expression of IL-1 receptor antagonist and release of IL-1β in human islets
K Maedler, P Sergeev, JA Ehses, Z Mathe, D Bosco, T Berney, JM Dayer, ...
Proceedings of the National Academy of Sciences 101 (21), 8138-8143, 2004
3582004
Interleukin-6 regulates pancreatic α-cell mass expansion
H Ellingsgaard, JA Ehses, EB Hammar, L Van Lommel, R Quintens, ...
Proceedings of the national academy of sciences 105 (35), 13163-13168, 2008
3192008
Cytokine production by islets in health and diabetes: cellular origin, regulation and function
MY Donath, M Böni-Schnetzler, H Ellingsgaard, PA Halban, JA Ehses
Trends in Endocrinology & Metabolism 21 (5), 261-267, 2010
2792010
Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
JA Ehses, DT Meier, S Wueest, J Rytka, S Boller, PY Wielinga, ...
Diabetologia 53, 1795-1806, 2010
2722010
Low-and high-density lipoproteins modulate function, apoptosis, and proliferation of primary human and murine pancreatic β-cells
S Rutti, JA Ehses, RA Sibler, R Prazak, L Rohrer, S Georgopoulos, ...
Endocrinology 150 (10), 4521-4530, 2009
2552009
Resident macrophages mediate islet amyloid polypeptide–induced islet IL-1β production and β-cell dysfunction
CY Westwell-Roper, JA Ehses, CB Verchere
Diabetes 63 (5), 1698-1711, 2014
2412014
Glucose-dependent insulinotropic polypeptide promotes β-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen …
JA Ehses, VR Casilla, TIM Doty, JA Pospisilik, KD Winter, HU Demuth, ...
Endocrinology 144 (10), 4433-4445, 2003
2222003
IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction
C Westwell-Roper, DL Dai, G Soukhatcheva, KJ Potter, N van Rooijen, ...
The journal of immunology 187 (5), 2755-2765, 2011
2122011
Insulin inhibits IL-10–mediated regulatory T cell function: implications for obesity
JM Han, SJ Patterson, M Speck, JA Ehses, MK Levings
The Journal of Immunology 192 (2), 623-629, 2014
1752014
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