| An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element MR Mansour, BJ Abraham, L Anders, A Berezovskaya, A Gutierrez, ... Science 346 (6215), 1373-1377, 2014 | 838 | 2014 |
| Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism DA Oldridge, AC Wood, N Weichert-Leahey, I Crimmins, R Sussman, ... Nature 528 (7582), 418-421, 2015 | 301 | 2015 |
| Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry AD Durbin, MW Zimmerman, NV Dharia, BJ Abraham, AB Iniguez, ... Nature genetics 50 (9), 1240-1246, 2018 | 220 | 2018 |
| Recurrent focal copy-number changes and loss of heterozygosity implicate two noncoding RNAs and one tumor suppressor gene at chromosome 3q13. 31 in osteosarcoma I Pasic, A Shlien, AD Durbin, DJ Stavropoulos, B Baskin, PN Ray, ... Cancer research 70 (1), 160-171, 2010 | 199 | 2010 |
| MYC drives a subset of high-risk pediatric neuroblastomas and is activated through mechanisms including enhancer hijacking and focal enhancer amplification MW Zimmerman, Y Liu, S He, AD Durbin, BJ Abraham, J Easton, Y Shao, ... Cancer discovery 8 (3), 320-335, 2018 | 195 | 2018 |
| Advances towards understanding heart valve response to injury AD Durbin, AI Gotlieb Cardiovascular Pathology 11 (2), 69-77, 2002 | 166 | 2002 |
| A first-generation pediatric cancer dependency map NV Dharia, G Kugener, LM Guenther, CF Malone, AD Durbin, AL Hong, ... Nature Genetics 53 (4), 529-538, 2021 | 87 | 2021 |
| EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma AD Durbin, T Wang, VK Wimalasena, MW Zimmerman, D Li, NV Dharia, ... Cancer Discovery 12 (3), 730-751, 2022 | 70 | 2022 |
| ASCL1 is a MYCN-and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry L Wang, TK Tan, AD Durbin, MW Zimmerman, BJ Abraham, SH Tan, ... Nature communications 10 (1), 5622, 2019 | 68 | 2019 |
| The NOTCH1/SNAIL1/MEF2C pathway regulates growth and self-renewal in embryonal rhabdomyosarcoma MS Ignatius, MN Hayes, R Lobbardi, EY Chen, KM McCarthy, P Sreenivas, ... Cell reports 19 (11), 2304-2318, 2017 | 63 | 2017 |
| ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression H Shi, T Tao, BJ Abraham, AD Durbin, MW Zimmerman, C Kadoch, ... Science Advances 6 (29), eaaz3440, 2020 | 59 | 2020 |
| JNK1 determines the oncogenic or tumor-suppressive activity of the integrin-linked kinase in human rhabdomyosarcoma AD Durbin, GR Somers, M Forrester, M Pienkowska, GE Hannigan, ... The Journal of clinical investigation 119 (6), 1558-1570, 2009 | 55 | 2009 |
| Expression of insulin-like growth factor pathway proteins in rhabdomyosarcoma: IGF-2 expression is associated with translocation-negative tumors S Makawita, M Ho, AD Durbin, PS Thorner, D Malkin, GR Somers Pediatric and Developmental Pathology 12 (2), 127-135, 2009 | 47 | 2009 |
| The CXCR4-SDF1α axis is a critical mediator of rhabdomyosarcoma metastatic signaling induced by bone marrow stroma B Strahm, AD Durbin, E Sexsmith, D Malkin Clinical & experimental metastasis 25 (1), 1-10, 2008 | 46 | 2008 |
| Using chemical epigenetics to target cancer VK Wimalasena, T Wang, LH Sigua, AD Durbin, J Qi Molecular cell 78 (6), 1086-1095, 2020 | 43 | 2020 |
| Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma MW Zimmerman, AD Durbin, S He, F Oppel, H Shi, T Tao, Z Li, ... Science Advances 7 (43), eabe0834, 2021 | 34 | 2021 |
| LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors T Tao, H Shi, L Mariani, BJ Abraham, AD Durbin, MW Zimmerman, ... Proceedings of the National Academy of Sciences 117 (28), 16516-16526, 2020 | 33 | 2020 |
| Malignant peripheral nerve sheath tumors AD Durbin, DH Ki, S He, AT Look Cancer and Zebrafish: mechanisms, techniques, and models, 495-530, 2016 | 30 | 2016 |
| Synthetic lethal interaction between the ESCRT paralog enzymes VPS4A and VPS4B in cancers harboring loss of chromosome 18q or 16q JE Neggers, BR Paolella, A Asfaw, MV Rothberg, TA Skipper, A Yang, ... Cell Reports 33 (11), 2020 | 29 | 2020 |
| The Estrogen Receptor Pathway in Rhabdomyosarcoma: A Role for Estrogen Receptor-β in Proliferation and Response to the Antiestrogen 4′ OH-Tamoxifen JA Greenberg, S Somme, HE Russnes, AD Durbin, D Malkin Cancer research 68 (9), 3476-3485, 2008 | 28 | 2008 |
