Lasse Sinkkonen
Lasse Sinkkonen
Head of the Epigenetics Team, University of Luxembourg
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Cited by
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MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells
L Sinkkonen, T Hugenschmidt, P Berninger, D Gaidatzis, F Mohn, ...
Nature structural & molecular biology 15 (3), 259-267, 2008
The human peroxisome proliferator-activated receptor δ gene is a primary target of 1α, 25-dihydroxyvitamin D3 and its nuclear receptor
TW Dunlop, S Väisänen, C Frank, F Molnár, L Sinkkonen, C Carlberg
Journal of molecular biology 349 (2), 248-260, 2005
Neurodegeneration by activation of the microglial complement–phagosome pathway
LG Bodea, Y Wang, B Linnartz-Gerlach, J Kopatz, L Sinkkonen, ...
Journal of Neuroscience 34 (25), 8546-8556, 2014
Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1α, 25-dihydroxyvitamin D3
S Väisänen, TW Dunlop, L Sinkkonen, C Frank, C Carlberg
Journal of molecular biology 350 (1), 65-77, 2005
Gene-pair expression signatures reveal lineage control
M Heinäniemi, M Nykter, R Kramer, A Wienecke-Baldacchino, ...
Nature methods 10 (6), 577-583, 2013
Dicer is associated with ribosomal DNA chromatin in mammalian cells
L Sinkkonen, T Hugenschmidt, W Filipowicz, P Svoboda
PloS one 5 (8), e12175, 2010
Dataset integration identifies transcriptional regulation of microRNA genes by PPARγ in differentiating mouse 3T3-L1 adipocytes
E John, A Wienecke-Baldacchino, M Liivrand, M Heinäniemi, C Carlberg, ...
Nucleic acids research 40 (10), 4446-4460, 2012
Regulation of the human cyclin C gene via multiple vitamin D 3 -responsive regions in its promoter
L Sinkkonen, M Malinen, K Saavalainen, S Väisänen, C Carlberg
Nucleic acids research 33 (8), 2440-2451, 2005
Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network
M Galhardo, L Sinkkonen, P Berninger, J Lin, T Sauter, M Heinäniemi
Nucleic acids research 42 (3), 1474-1496, 2014
TREM2 triggers microglial density and age‐related neuronal loss
B Linnartz‐Gerlach, LG Bodea, C Klaus, A Ginolhac, R Halder, ...
Glia 67 (3), 539-550, 2019
Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture
M Bouvy-Liivrand, A Hernández de Sande, P Pölönen, J Mehtonen, ...
Nucleic acids research 45 (17), 9837-9849, 2017
Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network
MP Pacheco, E John, T Kaoma, M Heinäniemi, N Nicot, L Vallar, JL Bueb, ...
BMC genomics 16 (1), 1-24, 2015
Controlling the chromatin organization of vitamin D target genes by multiple vitamin D receptor binding sites
C Carlberg, TW Dunlop, A Saramäki, L Sinkkonen, M Matilainen, ...
The Journal of steroid biochemistry and molecular biology 103 (3-5), 338-343, 2007
Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis
M Lahnalampi, M Heinäniemi, L Sinkkonen, M Wabitsch, C Carlberg
PloS one 5 (9), e12991, 2010
Combinatorial regulation of lipoprotein lipase by microRNAs during mouse adipogenesis
M Bouvy-Liivrand, M Heinäniemi, E John, JG Schneider, T Sauter, ...
RNA biology 11 (1), 76-91, 2014
Missing heritability in Parkinson’s disease: the emerging role of non-coding genetic variation
J Ohnmacht, P May, L Sinkkonen, R Krüger
Journal of Neural Transmission 127 (5), 729-748, 2020
Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients
SL Nickels, J Walter, S Bolognin, D Gérard, C Jaeger, X Qing, J Tisserand, ...
Parkinsonism & Related Disorders 67, 48-55, 2019
Temporal enhancer profiling of parallel lineages identifies AHR and GLIS1 as regulators of mesenchymal multipotency
D Gérard, F Schmidt, A Ginolhac, M Schmitz, R Halder, P Ebert, ...
Nucleic acids research 47 (3), 1141-1163, 2019
Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice
C Klaus, JN Hansen, A Ginolhac, D Gérard, VS Gnanapragassam, ...
Neurobiology of Aging 88, 91-107, 2020
Phagocytosis‐related NADPH oxidase 2 subunit gp91phox contributes to neurodegeneration after repeated systemic challenge with lipopolysaccharides
A Shahraz, J Wißfeld, A Ginolhac, M Mathews, L Sinkkonen, H Neumann
Glia 69 (1), 137-150, 2021
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