Simon Langdon
Simon Langdon
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Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo [5, 1-d]-1, 2, 3, 5-tetrazin-4 (3H)-one (CCRG 81045; M & B 39831), a novel drug with potential…
MFG Stevens, JA Hickman, SP Langdon, D Chubb, L Vickers, R Stone, ...
Cancer research 47 (22), 5846-5852, 1987
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ...
Breast Cancer Research 15 (5), 1-37, 2013
Bone marrow angiogenesis in 400 patients with monoclonal gammopathy of undetermined significance, multiple myeloma, and primary amyloidosis
SV Rajkumar, RA Mesa, R Fonseca, G Schroeder, MF Plevak, ...
Clinical cancer research 8 (7), 2210-2216, 2002
Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma
W Sakai, EM Swisher, C Jacquemont, KV Chandramohan, FJ Couch, ...
Cancer research 69 (16), 6381-6386, 2009
Characterization and properties of nine human ovarian adenocarcinoma cell lines
SP Langdon, SS Lawrie, FG Hay, MM Hawkes, A McDonald, IP Hayward, ...
Cancer research 48 (21), 6166-6172, 1988
The prognostic value of epidermal growth factor receptor mRNA expression in primary ovarian cancer.
JM Bartlett, SP Langdon, BJ Simpson, M Stewart, D Katsaros, P Sismondi, ...
British journal of cancer 73 (3), 301, 1996
Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system
A Koussounadis, SP Langdon, IH Um, DJ Harrison, VA Smith
Scientific reports 5, 10775, 2015
Quantitative analysis of changes in ER, PR and HER2 expression in primary breast cancer and paired nodal metastases
SJ Aitken, JS Thomas, SP Langdon, DJ Harrison, D Faratian
Annals of Oncology 21 (6), 1254-1261, 2010
Antiestrogen therapy is active in selected ovarian cancer cases: the use of letrozole in estrogen receptor–positive patients
JF Smyth, C Gourley, G Walker, MJ MacKean, A Stevenson, ...
Clinical Cancer Research 13 (12), 3617-3622, 2007
Systems biology reveals new strategies for personalizing cancer medicine and confirms the role of PTEN in resistance to trastuzumab
D Faratian, A Goltsov, G Lebedeva, A Sorokin, S Moodie, P Mullen, C Kay, ...
Cancer research 69 (16), 6713-6720, 2009
Growth of small cell lung cancer cells: stimulation by multiple neuropeptides and inhibition by broad spectrum antagonists in vitro and in vivo
T Sethi, S Langdon, J Smyth, E Rozengurt
Cancer Research 52 (9 Supplement), 2737s-2742s, 1992
New strategies for targeting the hypoxic tumour microenvironment in breast cancer
C Ward, SP Langdon, P Mullen, AL Harris, DJ Harrison, CT Supuran, ...
Cancer treatment reviews 39 (2), 171-179, 2013
Estrogen receptor-α mediates gene expression changes and growth response in ovarian cancer cells exposed to estrogen
AJM O’Donnell, KG Macleod, DJ Burns, JF Smyth, SP Langdon
Endocrine-related cancer 12 (4), 851-866, 2005
CA125 response is associated with estrogen receptor expression in a phase II trial of letrozole in ovarian cancer: identification of an endocrine-sensitive subgroup
A Bowman, H Gabra, SP Langdon, A Lessells, M Stewart, A Young, ...
Clinical cancer research 8 (7), 2233-2239, 2002
Expression of the heat shock protein HSP27 in human ovarian cancer.
SP Langdon, GJ Rabiasz, GL Hirst, RJ King, RA Hawkins, JF Smyth, ...
Clinical Cancer Research 1 (12), 1603-1609, 1995
Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma
SL Cooke, CKY Ng, N Melnyk, MJ Garcia, T Hardcastle, J Temple, ...
Oncogene 29 (35), 4905-4913, 2010
Altered ErbB receptor signaling and gene expression in cisplatin-resistant ovarian cancer
K Macleod, P Mullen, J Sewell, G Rabiasz, S Lawrie, E Miller, JF Smyth, ...
Cancer research 65 (15), 6789-6800, 2005
High antitumour activity of ET743 against human tumour xenografts from melanoma, non-small-cell lung and ovarian cancer
HR Hendriks, HH Fiebig, R Giavazzi, SP Langdon, JM Jimeno, ...
Annals of Oncology 10 (10), 1233-1240, 1999
Broad spectrum neuropeptide antagonists inhibit the growth of small cell lung cancer in vivo
S Langdon, T Sethi, A Ritchie, M Muir, J Smyth, E Rozengurt
Cancer research 52 (16), 4554-4557, 1992
Phase II preclinical drug screening in human tumor xenografts: a first European multicenter collaborative study
E Boven, B Winograd, DP Berger, MP Dumont, BJM Braakhuis, Fodstad, ...
Cancer research 52 (21), 5940-5947, 1992
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