Jesse D. Bloom
Jesse D. Bloom
Fred Hutch Cancer Research Center; University of Washington; Howard Hughes Medical Institute
Verified email at - Homepage
Cited by
Cited by
Protein stability promotes evolvability
JD Bloom, ST Labthavikul, CR Otey, FH Arnold
Proceedings of the National Academy of Sciences 103 (15), 5869-5874, 2006
Why highly expressed proteins evolve slowly
DA Drummond, JD Bloom, C Adami, CO Wilke, FH Arnold
Proceedings of the National Academy of Sciences 102 (40), 14338-14343, 2005
Permissive secondary mutations enable the evolution of influenza oseltamivir resistance
JD Bloom, LI Gong, D Baltimore
Science 328 (5983), 1272-1275, 2010
In the light of directed evolution: pathways of adaptive protein evolution
JD Bloom, FH Arnold
Proceedings of the National Academy of Sciences 106 (Supplement 1), 9995-10000, 2009
Evolving strategies for enzyme engineering
JD Bloom, MM Meyer, P Meinhold, CR Otey, D MacMillan, FH Arnold
Current opinion in structural biology 15 (4), 447-452, 2005
Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
TN Starr, AJ Greaney, SK Hilton, D Ellis, KHD Crawford, AS Dingens, ...
Cell 182 (5), 1295-1310. e20, 2020
Thermodynamic prediction of protein neutrality
JD Bloom, JJ Silberg, CO Wilke, DA Drummond, C Adami, FH Arnold
Proceedings of the National Academy of Sciences 102 (3), 606-611, 2005
Stability-mediated epistasis constrains the evolution of an influenza protein
LI Gong, MA Suchard, JD Bloom
Elife 2, e00631, 2013
Comprehensive mapping of mutations to the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human serum antibodies
AJ Greaney, AN Loes, KHD Crawford, TN Starr, KD Malone, HY Chu, ...
bioRxiv, 2020.12. 31.425021, 2021
Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 spike protein for neutralization assays
KHD Crawford, R Eguia, AS Dingens, AN Loes, KD Malone, CR Wolf, ...
Viruses 12 (5), 513, 2020
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition
AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein, AN Loes, SK Hilton, ...
Cell host & microbe 29 (1), 44-57. e9, 2021
Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with a high attack rate
A Addetia, KHD Crawford, A Dingens, H Zhu, P Roychoudhury, ML Huang, ...
Journal of clinical microbiology 58 (11), 2020
Structure-guided recombination creates an artificial family of cytochromes P450
CR Otey, M Landwehr, JB Endelman, K Hiraga, JD Bloom, FH Arnold
PLoS Biol 4 (5), e112, 2006
A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments
Y Li, DA Drummond, AM Sawayama, CD Snow, JD Bloom, FH Arnold
Nature biotechnology 25 (9), 1051-1056, 2007
Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013–2014 influenza season
SL Linderman, BS Chambers, SJ Zost, K Parkhouse, Y Li, C Herrmann, ...
Proceedings of the National Academy of Sciences 111 (44), 15798-15803, 2014
Structural determinants of the rate of protein evolution in yeast
JD Bloom, DA Drummond, FH Arnold, CO Wilke
Molecular biology and evolution 23 (9), 1751-1761, 2006
The interface of protein structure, protein biophysics, and molecular evolution
DA Liberles, SA Teichmann, I Bahar, U Bastolla, J Bloom, ...
Protein Science 21 (6), 769-785, 2012
Apparent dependence of protein evolutionary rate on number of interactions is linked to biases in protein–protein interactions data sets
JD Bloom, C Adami
BMC evolutionary biology 3 (1), 1-10, 2003
Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution
JD Bloom, PA Romero, Z Lu, FH Arnold
Biology direct 2 (1), 1-19, 2007
Thermodynamics of neutral protein evolution
JD Bloom, A Raval, CO Wilke
Genetics 175 (1), 255-266, 2007
The system can't perform the operation now. Try again later.
Articles 1–20