| A toolkit and benchmark study for FRET-restrained high-precision structural modeling S Kalinin, T Peulen, S Sindbert, PJ Rothwell, S Berger, T Restle, ... Nature methods 9 (12), 1218-1225, 2012 | 456 | 2012 |
| Structure and mechanism of DNA polymerases PJ Rothwell, G Waksman Advances in protein chemistry 71, 401-440, 2005 | 336 | 2005 |
| Accurate single-molecule FRET studies using multiparameter fluorescence detection E Sisamakis, A Valeri, S Kalinin, PJ Rothwell, CAM Seidel Methods in enzymology 475, 455-514, 2010 | 291 | 2010 |
| Multiparameter single-molecule fluorescence spectroscopy reveals heterogeneity of HIV-1 reverse transcriptase: primer/template complexes PJ Rothwell, S Berger, O Kensch, S Felekyan, M Antonik, BM Wöhrl, ... Proceedings of the National Academy of Sciences 100 (4), 1655-1660, 2003 | 274 | 2003 |
| Motions of the fingers subdomain of klentaq1 are fast and not rate limiting: implications for the molecular basis of fidelity in DNA polymerases PJ Rothwell, V Mitaksov, G Waksman Molecular cell 19 (3), 345-355, 2005 | 154 | 2005 |
| Single-molecule multiparameter fluorescence spectroscopy reveals directional MutS binding to mismatched bases in DNA M Cristovao, E Sisamakis, MM Hingorani, AD Marx, CP Jung, PJ Rothwell, ... Nucleic acids research 40 (12), 5448-5464, 2012 | 63 | 2012 |
| A Pre-equilibrium before Nucleotide Binding Limits Fingers Subdomain Closure by Klentaq1*♦ PJ Rothwell, G Waksman Journal of biological chemistry 282 (39), 28884-28892, 2007 | 59 | 2007 |
| Comparative analysis of enzymatically produced novel linear DNA constructs with plasmids for use as DNA vaccines AA Walters, E Kinnear, RJ Shattock, JU McDonald, LJ Caproni, N Porter, ... Gene therapy 21 (7), 645-652, 2014 | 44 | 2014 |
| Insight into the mechanism of a peptide inhibitor of HIV reverse transcriptase dimerization J Depollier, ML Hourdou, G Aldrian-Herrada, P Rothwell, T Restle, ... Biochemistry 44 (6), 1909-1918, 2005 | 36 | 2005 |
| Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model A Allen, C Wang, LJ Caproni, G Sugiyarto, E Harden, LR Douglas, ... Cancer Immunology, Immunotherapy 67, 627-638, 2018 | 35 | 2018 |
| Single molecule FCS-based oxygen sensor (O2-FCSensor): a new intrinsically calibrated oxygen sensor utilizing fluorescence correlation spectroscopy (FCS) with single … N Opitz, PJ Rothwell, B Oeke, P Schwille Sensors and Actuators B: Chemical 96 (1-2), 460-467, 2003 | 34 | 2003 |
| dNTP-dependent conformational transitions in the fingers subdomain of Klentaq1 DNA polymerase: insights into the role of the “nucleotide-binding” state PJ Rothwell, WJ Allen, E Sisamakis, S Kalinin, S Felekyan, J Widengren, ... Journal of Biological Chemistry 288 (19), 13575-13591, 2013 | 33 | 2013 |
| Novel synthetic plasmid and Doggybone™ DNA vaccines induce neutralizing antibodies and provide protection from lethal influenza challenge in mice VL Scott, A Patel, DO Villarreal, SE Hensley, E Ragwan, J Yan, ... Human Vaccines & Immunotherapeutics 11 (8), 1972-1982, 2015 | 30 | 2015 |
| An intramolecular FRET system monitors fingers subdomain opening in Klentaq1 WJ Allen, PJ Rothwell, G Waksman Protein Science 17 (3), 401-408, 2008 | 30 | 2008 |
| Doggybone™ DNA: an advanced platform for AAV production K Karbowniczek, J Extance, S Milsom, V Lukashchuk, K Bowes, ... Immuno-oncology Insights, 2017 | 22 | 2017 |
| dbDNA™: An advanced platform for genetic medicines T Adie, I Orefo, D Kysh, K Kondas, S Thapa, J Extance, T Duncan, ... Drug Discovery Today 27 (2), 374-377, 2022 | 7 | 2022 |
| Isothermal DNA amplification by a novel and non-ubiquitous Thermus polymerase A S Hjorleifsdottir, T Blondal, A Ævarsson, O H Fridjónsson, S Ernstsson, ... Current Biotechnology 3 (1), 76-86, 2014 | 3 | 2014 |
| Closed linear DNA production A Thomas, N Porter, P Rothwell US Patent 11,505,821, 2022 | 2 | 2022 |
| The unusual linear plasmid generating systems of prokaryotes SE Knott, SA Milsom, PJ Rothwell Bacteriophages-Perspectives and Future, 2019 | 2 | 2019 |
| Synthesis apparatus and method N Porter, PJ Rothwell US Patent 10,286,399, 2019 | 2 | 2019 |
Roger GoodyProfessor Max-Planck-Institute, DortmundGeverifieerd e-mailadres voor mpi-dortmund.mpg.de
