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Brittany L. Hartwell
Brittany L. Hartwell
Assistant Professor, University of Minnesota Department of Biomedical Engineering
Verified email at umn.edu
Title
Cited by
Cited by
Year
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity
M Silva, Y Kato, MB Melo, I Phung, BL Freeman, Z Li, K Roh, ...
Science immunology 6 (66), eabf1152, 2021
722021
Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice
NC Dalvie, SA Rodriguez-Aponte, BL Hartwell, LH Tostanoski, ...
Proceedings of the National Academy of Sciences 118 (38), e2106845118, 2021
682021
Multivalent nanomaterials: learning from vaccines and progressing to antigen-specific immunotherapies
BL Hartwell, L Antunez, BP Sullivan, S Thati, JO Sestak, C Berkland
Journal of pharmaceutical sciences 104 (2), 346-361, 2015
462015
Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity
BL Hartwell, MB Melo, P Xiao, AA Lemnios, N Li, JYH Chang, J Yu, ...
Science translational medicine 14 (654), eabn1413, 2022
442022
Codelivery of antigen and an immune cell adhesion inhibitor is necessary for efficacy of soluble antigen arrays in experimental autoimmune encephalomyelitis
JO Sestak, BP Sullivan, S Thati, L Northrup, B Hartwell, L Antunez, ...
Molecular Therapy-Methods & Clinical Development 1, 2014
442014
Soluble antigen arrays disarm antigen-specific B cells to promote lasting immune tolerance in experimental autoimmune encephalomyelitis
BL Hartwell, CJ Pickens, M Leon, L Northrup, MA Christopher, JD Griffin, ...
Journal of autoimmunity 93, 76-88, 2018
332018
Co-delivery of autoantigen and b7 pathway modulators suppresses experimental autoimmune encephalomyelitis
L Northrup, JO Sestak, BP Sullivan, S Thati, BL Hartwell, TJ Siahaan, ...
The AAPS journal 16, 1204-1213, 2014
322014
Multivalent soluble antigen arrays exhibit high avidity binding and modulation of B cell receptor-mediated signaling to drive efficacy against experimental autoimmune …
BL Hartwell, CJ Pickens, M Leon, C Berkland
Biomacromolecules 18 (6), 1893-1907, 2017
282017
Antigen-specific binding of multivalent soluble antigen arrays induces receptor clustering and impedes B cell receptor mediated signaling
BL Hartwell, FJ Martinez-Becerra, J Chen, H Shinogle, M Sarnowski, ...
Biomacromolecules 17 (3), 710-722, 2016
282016
Routes of administration and dose optimization of soluble antigen arrays in mice with experimental autoimmune encephalomyelitis
S Thati, C Kuehl, B Hartwell, J Sestak, T Siahaan, ML Forrest, C Berkland
Journal of pharmaceutical sciences 104 (2), 714-721, 2015
262015
Combined PET and whole-tissue imaging of lymphatic-targeting vaccines in non-human primates
JT Martin, BL Hartwell, SC Kumarapperuma, MB Melo, DG Carnathan, ...
Biomaterials 275, 120868, 2021
212021
Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters
NC Dalvie, SA Rodriguez-Aponte, BL Hartwell, LH Tostanoski, ...
BioRxiv, 2021
192021
Molecular dynamics of multivalent soluble antigen arrays support a two-signal co-delivery mechanism in the treatment of experimental autoimmune encephalomyelitis
BL Hartwell, A Smalter Hall, D Swafford, BP Sullivan, A Garza, JO Sestak, ...
Molecular pharmaceutics 13 (2), 330-343, 2016
162016
Co-delivery of autoantigen and dexamethasone in incomplete Freund's adjuvant ameliorates experimental autoimmune encephalomyelitis
L Northrup, JD Griffin, MA Christopher, LR Antunez, BL Hartwell, ...
Journal of Controlled Release 266, 156-165, 2017
142017
Acute B-cell inhibition by soluble antigen arrays is valency-dependent and predicts immunomodulation in splenocytes
JD Griffin, MA Leon, JR Salash, M Shao, BL Hartwell, CJ Pickens, ...
Biomacromolecules 20 (5), 2115-2122, 2019
82019
Screening immunomodulators to skew the antigen-specific autoimmune response
L Northrup, BP Sullivan, BL Hartwell, A Garza, C Berkland
Molecular pharmaceutics 14 (1), 66-80, 2017
72017
Smalter Hall A; Swafford D; Sullivan BP; Garza A; Sestak JO; Northrup L; Berkland C
BL Hartwell
Molecular Dynamics of Multivalent Soluble Antigen Arrays Support a Two …, 2016
72016
Transmucosal amphiphile-protein conjugate vaccine
DJ Irvine, BL Hartwell
US Patent App. 18/117,752, 2023
2023
Elucidating Vaccine Trafficking Mechanisms using Multimodal Imaging
BL Hartwell, J Martin, JYH Chang, SC Kumarapperuma, RM Ruprecht, ...
Microscopy and Microanalysis 29 (Supplement_1), 1068-1068, 2023
2023
Multivalent Soluble Antigen Arrays Target Antigen Presenting B Cells and Dampen Antigen-Specific Signaling to Promote Therapeutic Efficacy in Multiple Sclerosis
B Hartwell
2017 AIChE Annual Meeting, 2017
2017
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Articles 1–20