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Michael O'Neill
Michael O'Neill
Head of Molecular Pathology, Eli Lilly & Co. Ltd.
Geverifieerd e-mailadres voor lilly.com
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A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity
Z Ahmed, J Cooper, TK Murray, K Garn, E McNaughton, H Clarke, ...
Acta neuropathologica 127, 667-683, 2014
4942014
Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression
X Chai, S Wu, TK Murray, R Kinley, CV Cella, H Sims, N Buckner, ...
Journal of Biological Chemistry 286 (39), 34457-34467, 2011
3932011
6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cδ
K Hanrott, L Gudmunsen, MJ O’Neill, S Wonnacott
Journal of biological chemistry 281 (9), 5373-5382, 2006
3152006
Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment
G De Foubert, SL Carney, CS Robinson, EJ Destexhe, R Tomlinson, ...
Neuroscience 128 (3), 597-604, 2004
3012004
Conformation determines the seeding potencies of native and recombinant Tau aggregates
B Falcon, A Cavallini, R Angers, S Glover, TK Murray, L Barnham, ...
Journal of biological chemistry 290 (2), 1049-1065, 2015
2842015
AMPA receptor potentiators for the treatment of CNS disorders
MJ O'Neill, D Bleakman, DM Zimmerman, ES Nisenbaum
Current Drug Targets-CNS & Neurological Disorders 3 (3), 181-194, 2004
2782004
The role of neuronal nicotinic acetylcholine receptors in acute and chronic neurodegeneration
MJ O'neill, TK Murray, V Lakics, NP Visanji, S Duty
Current Drug Targets-CNS & Neurological Disorders 1 (4), 399-411, 2002
2772002
Impaired glymphatic function and clearance of tau in an Alzheimer’s disease model
IF Harrison, O Ismail, A Machhada, N Colgan, Y Ohene, P Nahavandi, ...
Brain 143 (8), 2576-2593, 2020
2622020
Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease
N Colgan, B Siow, JM O'Callaghan, IF Harrison, JA Wells, HE Holmes, ...
Neuroimage 125, 739-744, 2016
2182016
A common mucosal immunologic system involving the bronchus, breast and bowel
J Bienenstock, M McDermott, D Befus, M O’Neill
Secretory Immunity and Infection: Proceedings of the International Symposium …, 1978
2151978
Antagonists of GLUK5-containing kainate receptors prevent pilocarpine-induced limbic seizures
I Smolders, ZA Bortolotto, VRJ Clarke, R Warre, GM Khan, MJ O'neill, ...
Nature neuroscience 5 (8), 796-804, 2002
1812002
Cytotoxic activities of gut mucosal lymphoid cells in guinea pigs
F Arnaud-Battandier, BM Bundy, M O'Neill, J Bienenstock, DL Nelson
The Journal of Immunology 121 (3), 1059-1065, 1978
1681978
An AMPA receptor potentiator modulates hippocampal expression of BDNF: an in vivo study
M Mackowiak, MJ O’Neill, CA Hicks, D Bleakman, P Skolnick
Neuropharmacology 43 (1), 1-10, 2002
1592002
The IMPROVE guidelines (ischaemia models: procedural refinements of in vivo experiments)
N Percie du Sert, A Alfieri, SM Allan, HVO Carswell, GA Deuchar, TD Farr, ...
Journal of Cerebral Blood Flow & Metabolism 37 (11), 3488-3517, 2017
1502017
Short fibrils constitute the major species of seed-competent tau in the brains of mice transgenic for human P301S tau
SJ Jackson, C Kerridge, J Cooper, A Cavallini, B Falcon, CV Cella, ...
Journal of Neuroscience 36 (3), 762-772, 2016
1502016
The adenosine A2A antagonist KF17837 reverses the locomotor suppression and tremulous jaw movements induced by haloperidol in rats: possible relevance to parkinsonism
M Correa, A Wisniecki, A Betz, DR Dobson, MF O’Neill, MJ O’Neill, ...
Behavioural brain research 148 (1-2), 47-54, 2004
1462004
Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist,(+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366 …
V Bruno, G Battaglia, A Kingston, MJ O’neill, MV Catania, R Di Grezia, ...
Neuropharmacology 38 (2), 199-207, 1999
1441999
Decahydroisoquinolines: novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia
MJ O'Neill, A Bond, PL Ornstein, MA Ward, CA Hicks, K Hoo, D Bleakman, ...
Neuropharmacology 37 (10-11), 1211-1222, 1998
1411998
CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer’s disease
HJM Weir, TK Murray, PG Kehoe, S Love, EM Verdin, MJ O’Neill, JD Lane, ...
PloS one 7 (11), e48225, 2012
1322012
Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation …
M Keatinge, H Bui, A Menke, YC Chen, AM Sokol, Q Bai, F Ellett, ...
Human molecular genetics 24 (23), 6640-6652, 2015
1312015
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Artikelen 1–20