TREM2 Variants in Alzheimer's Disease R Guerreiro, A Wojtas, J Bras, M Carrasquillo, E Rogaeva, E Majounie, ... New England Journal of Medicine 368 (2), 117-127, 2013 | 3076 | 2013 |
Neurotransmitter receptors on microglia JM Pocock, H Kettenmann Trends in neurosciences 30 (10), 527-535, 2007 | 793 | 2007 |
Cannabinoids inhibit neurodegeneration in models of multiple sclerosis G Pryce, Z Ahmed, DJR Hankey, SJ Jackson, JL Croxford, JM Pocock, ... Brain 126 (10), 2191-2202, 2003 | 428 | 2003 |
Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor α-induced neurotoxicity in concert with microglial-derived Fas ligand DL Taylor, F Jones, ESFCS Kubota, JM Pocock Journal of Neuroscience 25 (11), 2952-2964, 2005 | 378 | 2005 |
Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease C Villegas-Llerena, A Phillips, P Garcia-Reitboeck, J Hardy, JM Pocock Current opinion in neurobiology 36, 74-81, 2016 | 277 | 2016 |
Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity DL Taylor, LT Diemel, JM Pocock Journal of Neuroscience 23 (6), 2150-2160, 2003 | 248 | 2003 |
Microglia release activators of neuronal proliferation mediated by activation of mitogen‐activated protein kinase, phosphatidylinositol‐3‐kinase/Akt and delta–Notch signalling … SC Morgan, DL Taylor, JM Pocock Journal of neurochemistry 90 (1), 89-101, 2004 | 227 | 2004 |
Microglial secreted cathepsin B induces neuronal apoptosis PJ Kingham, JM Pocock Journal of neurochemistry 76 (5), 1475-1484, 2001 | 210 | 2001 |
Insights into TREM2 biology by network analysis of human brain gene expression data P Forabosco, A Ramasamy, D Trabzuni, R Walker, C Smith, J Bras, ... Neurobiology of aging 34 (12), 2699-2714, 2013 | 191 | 2013 |
Apoptotic pathways mobilized in microglia and neurones as a consequence of chromogranin A‐induced microglial activation PJ Kingham, ML Cuzner, JM Pocock Journal of neurochemistry 73 (2), 538-547, 1999 | 186 | 1999 |
Activation of group II metabotropic glutamate receptors underlies microglial reactivity and neurotoxicity following stimulation with chromogranin A, a peptide up‐regulated in … DL Taylor, LT Diemel, ML Cuzner, JM Pocock Journal of neurochemistry 82 (5), 1179-1191, 2002 | 177 | 2002 |
Complement receptor 1 (CR1) and Alzheimer's disease H Crehan, P Holton, S Wray, J Pocock, R Guerreiro, J Hardy Immunobiology 217 (2), 244-250, 2012 | 144 | 2012 |
Human induced pluripotent stem cell-derived microglia-like cells harboring TREM2 missense mutations show specific deficits in phagocytosis P Garcia-Reitboeck, A Phillips, TM Piers, C Villegas-Llerena, M Butler, ... Cell Reports 24 (9), 2300-2311, 2018 | 143 | 2018 |
Branched Chain Amino Acids Induce Apoptosis in Neural Cells without Mitochondrial Membrane Depolarization or Cytochromec Release: Implications for … P Jouvet, P Rustin, DL Taylor, JM Pocock, U Felderhoff-Mueser, ... Molecular biology of the cell 11 (5), 1919-1932, 2000 | 142 | 2000 |
Neuronal surface glycolytic enzymes are autoantigen targets in post-streptococcal autoimmune CNS disease RC Dale, PM Candler, AJ Church, R Wait, JM Pocock, G Giovannoni Journal of neuroimmunology 172 (1-2), 187-197, 2006 | 138 | 2006 |
Microglial signalling cascades in neurodegenerative disease JM Pocock, AC Liddle Progress in brain research 132, 555-565, 2001 | 120 | 2001 |
The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans X Xiang, TM Piers, B Wefers, K Zhu, A Mallach, B Brunner, G Kleinberger, ... Molecular neurodegeneration 13, 1-14, 2018 | 115 | 2018 |
Microglia, Alzheimer's disease, and complement H Crehan, J Hardy, J Pocock International Journal of Alzheimer’s Disease 2012, 2012 | 111 | 2012 |
A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC‐derived microglia TM Piers, K Cosker, A Mallach, GT Johnson, R Guerreiro, J Hardy, ... The FASEB Journal 34 (2), 2436, 2020 | 101 | 2020 |
Wnt3a induces exosome secretion from primary cultured rat microglia C Hooper, R Sainz-Fuertes, S Lynham, A Hye, R Killick, A Warley, ... BMC neuroscience 13, 1-17, 2012 | 101 | 2012 |