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Jennifer Pocock
Jennifer Pocock
Institute of Neurology, University College London (UCL)
Geverifieerd e-mailadres voor ucl.ac.uk - Homepage
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TREM2 Variants in Alzheimer's Disease
R Guerreiro, A Wojtas, J Bras, M Carrasquillo, E Rogaeva, E Majounie, ...
New England Journal of Medicine 368 (2), 117-127, 2013
30762013
Neurotransmitter receptors on microglia
JM Pocock, H Kettenmann
Trends in neurosciences 30 (10), 527-535, 2007
7932007
Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
G Pryce, Z Ahmed, DJR Hankey, SJ Jackson, JL Croxford, JM Pocock, ...
Brain 126 (10), 2191-2202, 2003
4282003
Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor α-induced neurotoxicity in concert with microglial-derived Fas ligand
DL Taylor, F Jones, ESFCS Kubota, JM Pocock
Journal of Neuroscience 25 (11), 2952-2964, 2005
3782005
Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease
C Villegas-Llerena, A Phillips, P Garcia-Reitboeck, J Hardy, JM Pocock
Current opinion in neurobiology 36, 74-81, 2016
2772016
Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity
DL Taylor, LT Diemel, JM Pocock
Journal of Neuroscience 23 (6), 2150-2160, 2003
2482003
Microglia release activators of neuronal proliferation mediated by activation of mitogen‐activated protein kinase, phosphatidylinositol‐3‐kinase/Akt and delta–Notch signalling …
SC Morgan, DL Taylor, JM Pocock
Journal of neurochemistry 90 (1), 89-101, 2004
2272004
Microglial secreted cathepsin B induces neuronal apoptosis
PJ Kingham, JM Pocock
Journal of neurochemistry 76 (5), 1475-1484, 2001
2102001
Insights into TREM2 biology by network analysis of human brain gene expression data
P Forabosco, A Ramasamy, D Trabzuni, R Walker, C Smith, J Bras, ...
Neurobiology of aging 34 (12), 2699-2714, 2013
1912013
Apoptotic pathways mobilized in microglia and neurones as a consequence of chromogranin A‐induced microglial activation
PJ Kingham, ML Cuzner, JM Pocock
Journal of neurochemistry 73 (2), 538-547, 1999
1861999
Activation of group II metabotropic glutamate receptors underlies microglial reactivity and neurotoxicity following stimulation with chromogranin A, a peptide up‐regulated in …
DL Taylor, LT Diemel, ML Cuzner, JM Pocock
Journal of neurochemistry 82 (5), 1179-1191, 2002
1772002
Complement receptor 1 (CR1) and Alzheimer's disease
H Crehan, P Holton, S Wray, J Pocock, R Guerreiro, J Hardy
Immunobiology 217 (2), 244-250, 2012
1442012
Human induced pluripotent stem cell-derived microglia-like cells harboring TREM2 missense mutations show specific deficits in phagocytosis
P Garcia-Reitboeck, A Phillips, TM Piers, C Villegas-Llerena, M Butler, ...
Cell Reports 24 (9), 2300-2311, 2018
1432018
Branched Chain Amino Acids Induce Apoptosis in Neural Cells without Mitochondrial Membrane Depolarization or Cytochromec Release: Implications for …
P Jouvet, P Rustin, DL Taylor, JM Pocock, U Felderhoff-Mueser, ...
Molecular biology of the cell 11 (5), 1919-1932, 2000
1422000
Neuronal surface glycolytic enzymes are autoantigen targets in post-streptococcal autoimmune CNS disease
RC Dale, PM Candler, AJ Church, R Wait, JM Pocock, G Giovannoni
Journal of neuroimmunology 172 (1-2), 187-197, 2006
1382006
Microglial signalling cascades in neurodegenerative disease
JM Pocock, AC Liddle
Progress in brain research 132, 555-565, 2001
1202001
The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans
X Xiang, TM Piers, B Wefers, K Zhu, A Mallach, B Brunner, G Kleinberger, ...
Molecular neurodegeneration 13, 1-14, 2018
1152018
Microglia, Alzheimer's disease, and complement
H Crehan, J Hardy, J Pocock
International Journal of Alzheimer’s Disease 2012, 2012
1112012
A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC‐derived microglia
TM Piers, K Cosker, A Mallach, GT Johnson, R Guerreiro, J Hardy, ...
The FASEB Journal 34 (2), 2436, 2020
1012020
Wnt3a induces exosome secretion from primary cultured rat microglia
C Hooper, R Sainz-Fuertes, S Lynham, A Hye, R Killick, A Warley, ...
BMC neuroscience 13, 1-17, 2012
1012012
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