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Malene Urbanus
Malene Urbanus
Staff scientist, University of Toronto
Geverifieerd e-mailadres voor utoronto.ca
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YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase
PA Scotti, ML Urbanus, J Brunner, JWL de Gier, G von Heijne, ...
The EMBO journal 19 (4), 542-549, 2000
5052000
Mapping the cellular response to small molecules using chemogenomic fitness signatures
AY Lee, RP St. Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ...
Science 344 (6180), 208-211, 2014
2602014
Sec-dependent membrane protein insertion: sequential interaction of nascent FtsQ with SecY and YidC
ML Urbanus, PA Scotti, L Fröderberg, A Sääf, JWL de Gier, J Brunner, ...
EMBO reports 2 (6), 524-529, 2001
2362001
A conserved function of YidC in the biogenesis of respiratory chain complexes
M van der Laan, ML Urbanus, CM Ten Hagen-Jongman, N Nouwen, ...
Proceedings of the National Academy of Sciences 100 (10), 5801-5806, 2003
1882003
Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pHc in Saccharomyces cerevisiae.
R Orij, ML Urbanus, FJ Vizeacoumar, G Giaever, C Boone, C Nislow, ...
Genome Biology 13 (R80), 2012
1682012
Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors
MA Sukhai, S Prabha, R Hurren, AC Rutledge, AY Lee, ...
The Journal of clinical investigation 123 (1), 2012
1562012
Signal recognition particle (SRP)-mediated targeting and Sec-dependent translocation of an extracellular Escherichia coli protein
R Sijbrandi, ML Urbanus, M Corinne, HD Bernstein, B Oudega, BR Otto, ...
Journal of Biological Chemistry 278 (7), 4654-4659, 2003
1532003
Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila
ML Urbanus, AT Quaile, PJ Stogios, M Morar, C Rao, R Di Leo, ...
Molecular systems biology 12 (12), 893, 2016
1242016
Targeting, insertion, and localization of Escherichia coli YidC
ML Urbanus, L Fröderberg, D Drew, P Björk, JWL de Gier, J Brunner, ...
Journal of Biological Chemistry 277 (15), 12718-12723, 2002
1212002
SecA is not required for signal recognition particle-mediated targeting and initial membrane insertion of a nascent inner membrane protein
PA Scotti, QA Valent, EH Manting, ML Urbanus, AJM Driessen, B Oudega, ...
Journal of Biological Chemistry 274 (42), 29883-29888, 1999
1121999
Detection of cross-links between FtsH, YidC, HflK/C suggests a linked role for these proteins in quality control upon insertion of bacterial inner membrane proteins
E van Bloois, HL Dekker, L Fröderberg, ENG Houben, ML Urbanus, ...
FEBS letters 582 (10), 1419-1424, 2008
972008
Mixed-disulfide folding intermediates between thyroglobulin and endoplasmic reticulum resident oxidoreductases ERp57 and protein disulfide isomerase
B Di Jeso, Y Park, L Ulianich, AS Treglia, ML Urbanas, S High, P Arvan
Molecular and cellular biology 25 (22), 9793-9805, 2005
962005
YidC and SecY mediate membrane insertion of a Type I transmembrane domain
ENG Houben, ML Urbanus, M Van Der Laan, CM ten Hagen-Jongman, ...
Journal of Biological Chemistry 277 (39), 35880-35886, 2002
712002
Decreasing the chlorophyll a/b ratio in reconstituted LHCII: structural and functional consequences
FJ Kleima, S Hobe, F Calkoen, ML Urbanus, EJG Peterman, ...
Biochemistry 38 (20), 6587-6596, 1999
681999
Compound prioritization methods increase rates of chemical probe discovery in model organisms
IM Wallace, ML Urbanus, GM Luciani, AR Burns, MKL Han, H Wang, ...
Chemistry & biology 18 (10), 1273-1283, 2011
552011
Molecular characterization of LubX: functional divergence of the U-box fold by Legionella pneumophila
AT Quaile, ML Urbanus, PJ Stogios, B Nocek, T Skarina, AW Ensminger, ...
Structure 23 (8), 1459-1469, 2015
522015
Discovery of ubiquitin deamidases in the pathogenic arsenal of Legionella pneumophila
D Valleau, AT Quaile, H Cui, X Xu, E Evdokimova, C Chang, ME Cuff, ...
Cell reports 23 (2), 568-583, 2018
482018
Competitive genomic screens of barcoded yeast libraries
AM Smith, T Durbic, J Oh, M Urbanus, M Proctor, LE Heisler, G Giaever, ...
JoVE (Journal of Visualized Experiments), e2864, 2011
462011
The automated cell: compound and environment screening system (ACCESS) for chemogenomic screening
M Proctor, ML Urbanus, EL Fung, DF Jaramillo, RW Davis, C Nislow, ...
Yeast Systems Biology: Methods and Protocols, 239-269, 2011
362011
Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans
GM Luciani, L Magomedova, R Puckrin, ML Urbanus, IM Wallace, ...
Nature chemical biology 7 (12), 891-893, 2011
332011
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Artikelen 1–20