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Philip Knuckles
Philip Knuckles
F. Hoffman-La Roche AG
Verified email at roche.com
Title
Cited by
Cited by
Year
Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging
S Lugert, O Basak, P Knuckles, U Haussler, K Fabel, M Götz, CA Haas, ...
Cell stem cell 6 (5), 445-456, 2010
8152010
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl (2) d
P Knuckles, T Lence, IU Haussmann, D Jacob, N Kreim, SH Carl, ...
Genes & development 32 (5-6), 415-429, 2018
4902018
Molecular diversity subdivides the adult forebrain neural stem cell population
C Giachino, O Basak, S Lugert, P Knuckles, K Obernier, R Fiorelli, S Frank, ...
Stem cells 32 (1), 70-84, 2014
1542014
RNA fate determination through cotranscriptional adenosine methylation and microprocessor binding
P Knuckles, SH Carl, M Musheev, C Niehrs, A Wenger, M Bühler
Nature structural & molecular biology 24 (7), 561-569, 2017
1462017
Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs
P Knuckles, MA Vogt, S Lugert, M Milo, MMW Chong, GM Hautbergue, ...
Nature neuroscience 15 (7), 962-969, 2012
1402012
The H+ Vacuolar ATPase Maintains Neural Stem Cells in the Developing Mouse Cortex
C Lange, S Prenninger, P Knuckles, V Taylor, M Levin, F Calegari
Stem cells and development 20 (5), 843-850, 2011
912011
TDP-43 induces p53-mediated cell death of cortical progenitors and immature neurons
MA Vogt, Z Ehsaei, P Knuckles, A Higginbottom, MS Helmbrecht, ...
Scientific reports 8 (1), 8097, 2018
542018
Adenosine methylation as a molecular imprint defining the fate of RNA
P Knuckles, M Bühler
FEBS letters 592 (17), 2845-2859, 2018
492018
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1
T Welte, AC Tuck, P Papasaikas, SH Carl, M Flemr, P Knuckles, ...
Genes & development 33 (17-18), 1221-1235, 2019
322019
m6A RNA methylation of major satellite repeat transcripts facilitates chromatin association and RNA:DNA hybrid formation in mouse heterochromatin
TJ Katarzyna J Duda, Reagan W Ching, Lisa Jerabek, Nicholas Shukeir, Galina ...
Nucleic Acids Research, 2021
222021
A rare natural lipid induces neuroglobin expression to prevent amyloid oligomers toxicity and retinal neurodegeneration
HP Oamen, N Romero Romero, P Knuckles, J Saarikangas, ...
Aging Cell 21 (7), e13645, 2022
22022
Genome-Engineering Tools to Establish Accurate Reporter Cell Lines That Enable Identification of Therapeutic Strategies to Treat Friedreich’s Ataxia
R Villaseñor, L Miraglia, A Romero, B Tu, T Punga, P Knuckles, S Duss, ...
Journal of biomolecular screening 20 (6), 760-767, 2015
12015
Method for diagnosing cutaneous t-cell lymphoma diseases
P Nestorov, VK Tiwari, M Claassen, P Knuckles, SH CARL, E Guenova, ...
US Patent App. 17/789,340, 2023
2023
439 Cytometry and machine learning based approaches for diagnosis of malignant cells in Sézary syndrome
C Fassnacht, SH Carl, P Knuckles, E Varypataki, Y Tsai, E Guenova
Journal of Investigative Dermatology 142 (12), S256, 2022
2022
Mass cytometry and machine learning delineate tumor-defining cells in Sézary syndrome to allow discrimination from benign erythroderma
SH Carl, C Fassnacht, P Knuckles, EM Varypataki, YT Chang, YC Tsai, ...
European Journal of Cancer 156, S5-S6, 2021
2021
V-ATPase Maintains Neural Stem Cells in the Developing Mouse Cortex
C Lange, S Prenninger, P Knuckles, V Taylor, M Levin, F Calegari
Handbook of H+-ATPases, 413, 2014
2014
Role of Microprocessor in Neural Stem Cells
P Knuckles
Albert-Ludwigs University Freiburg im Breisgau, Germany, 2011
2011
INVENTORY OF SUPPLEMENTARY INFORMATION
S Lugert, O Basak, P Knuckles, U Haussler, K Fabel, M Gotz, CA Haas, ...
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