Josbert M Metselaar
Josbert M Metselaar
utrecht university, enceladus pharmaceuticals, university clinic aachen, university of twente
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Current trends and challenges in the clinical translation of nanoparticulate nanomedicines: pathways for translational development and commercialization
S Hua, MBC De Matos, JM Metselaar, G Storm
Frontiers in pharmacology 9, 790, 2018
Complete remission of experimental arthritis by joint targeting of glucocorticoids with long‐circulating liposomes
JM Metselaar, MHM Wauben, JPA Wagenaar‐Hilbers, OC Boerman, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2003
Improving solubility and chemical stability of natural compounds for medicinal use by incorporation into liposomes
M Coimbra, B Isacchi, L van Bloois, JS Torano, A Ket, X Wu, F Broere, ...
International journal of pharmaceutics 416 (2), 433-442, 2011
Drug targeting by long‐circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis
J Schmidt, JM Metselaar, MHM Wauben, KV Toyka, G Storm, R Gold
Brain 126 (8), 1895-1904, 2003
Role of complement activation in hypersensitivity reactions to doxil and hynic PEG liposomes: experimental and clinical studies
J Szebeni, L Baranyi, S Savay, J Milosevits, R Bunger, P Laverman, ...
Journal of liposome research 12 (1-2), 165-172, 2002
Multimodal clinical imaging to longitudinally assess a nanomedical anti-inflammatory treatment in experimental atherosclerosis
ME Lobatto, ZA Fayad, S Silvera, E Vucic, C Calcagno, V Mani, ...
Molecular pharmaceutics 7 (6), 2020-2029, 2010
A Novel Family of l-Amino Acid-Based Biodegradable Polymer−Lipid Conjugates for the Development of Long-Circulating Liposomes with Effective Drug-Targeting …
JM Metselaar, P Bruin, LWT de Boer, T de Vringer, C Snel, C Oussoren, ...
Bioconjugate chemistry 14 (6), 1156-1164, 2003
Challenges in nanomedicine clinical translation
JM Metselaar, T Lammers
Drug delivery and translational research 10, 721-725, 2020
Dexamethasone nanomedicines for COVID-19
T Lammers, AM Sofias, R Van der Meel, R Schiffelers, G Storm, F Tacke, ...
Nature nanotechnology 15 (8), 622-624, 2020
Prednisolone-containing liposomes accumulate in human atherosclerotic macrophages upon intravenous administration
FM van der Valk, DF van Wijk, ME Lobatto, HJ Verberne, G Storm, ...
Nanomedicine: nanotechnology, biology and medicine 11 (5), 1039-1046, 2015
Size-isolation of superparamagnetic iron oxide nanoparticles improves MRI, MPI and hyperthermia performance
SM Dadfar, D Camozzi, M Darguzyte, K Roemhild, P Varvarā, J Metselaar, ...
Journal of nanobiotechnology 18, 1-13, 2020
Liposomal drug formulations in the treatment of rheumatoid arthritis
JM van den Hoven, SR Van Tomme, JM Metselaar, B Nuijen, JH Beijnen, ...
Molecular pharmaceutics 8 (4), 1002-1015, 2011
Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes
L Quan, Y Zhang, BJ Crielaard, A Dusad, SM Lele, CJF Rijcken, ...
ACS nano 8 (1), 458-466, 2014
Liposome-encapsulated prednisolone phosphate inhibits growth of established tumors in mice
RM Schiffelers, JM Metselaar, MHAM Fens, APCA Janssen, G Molema, ...
Neoplasia 7 (2), 118-127, 2005
Liposomes in the treatment of inflammatory disorders
JM Metselaar, G Storm
Expert opinion on drug delivery 2 (3), 465-476, 2005
Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging
ME Lobatto, C Calcagno, A Millon, ML Senders, F Fay, PM Robson, ...
ACS nano 9 (2), 1837-1847, 2015
Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction
IE Allijn, BMS Czarny, X Wang, SY Chong, M Weiler, AE Da Silva, ...
Journal of controlled release 247, 127-133, 2017
Poly (amino acid) s: promising enzymatically degradable stealth coatings for liposomes
B Romberg, JM Metselaar, L Baranyi, CJ Snel, R Bünger, WE Hennink, ...
International journal of pharmaceutics 331 (2), 186-189, 2007
Antitumor activity of liposomal prednisolone phosphate depends on the presence of functional tumor-associated macrophages in tumor tissue
M Banciu, JM Metselaar, RM Schiffelers, G Storm
Neoplasia 10 (2), 108-117, 2008
Metallodrugs in cancer nanomedicine
Q Peņa, A Wang, O Zaremba, Y Shi, HW Scheeren, JM Metselaar, ...
Chemical society reviews 51 (7), 2544-2582, 2022
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Articles 1–20