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Oana Ursu
Oana Ursu
Scientist, Cellular and Tissue Genomics, Genentech
Verified email at gene.com - Homepage
Title
Cited by
Cited by
Year
Genetic control of chromatin states in humans involves local and distal chromosomal interactions
F Grubert, JB Zaugg, M Kasowski, O Ursu, DV Spacek, AR Martin, ...
Cell 162 (5), 1051-1065, 2015
3652015
Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens
DW Morgens, M Wainberg, EA Boyle, O Ursu, CL Araya, CK Tsui, ...
Nature communications 8 (1), 15178, 2017
3312017
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements
J Tycko, M Wainberg, GK Marinov, O Ursu, GT Hess, BK Ego, Aradhana, ...
Nature communications 10 (1), 4063, 2019
1012019
Measuring the reproducibility and quality of Hi-C data
GG Yardımcı, H Ozadam, MEG Sauria, O Ursu, KK Yan, T Yang, ...
Genome biology 20, 1-19, 2019
1002019
GenomeDISCO: a concordance score for chromosome conformation capture experiments using random walks on contact map graphs
O Ursu, N Boley, M Taranova, YXR Wang, GG Yardimci, W Stafford Noble, ...
Bioinformatics 34 (16), 2701-2707, 2018
922018
Massively parallel phenotyping of coding variants in cancer with Perturb-seq
O Ursu, JT Neal, E Shea, PI Thakore, L Jerby-Arnon, L Nguyen, D Dionne, ...
Nature biotechnology 40 (6), 896-905, 2022
63*2022
SAMNet: a network-based approach to integrate multi-dimensional high throughput datasets
SJC Gosline, SJ Spencer, O Ursu, E Fraenkel
Integrative biology 4 (11), 1415-1427, 2012
292012
Perspectives on ENCODE
F Abascal, R Acosta, NJ Addleman, J Adrian, V Afzal, B Aken, JA Akiyama
Nature 583 (7818), 693-699, 2020
152020
Structural and functional properties of mSWI/SNF chromatin remodeling complexes revealed through single-cell perturbation screens
JE Otto, O Ursu, AP Wu, EB Winter, MS Cuoco, S Ma, K Qian, BC Michel, ...
Molecular Cell 83 (8), 1350-1367. e7, 2023
92023
Unsupervised learning from noisy networks with applications to hi-c data
B Wang, J Zhu, A Pourshafeie, O Ursu, S Batzoglou, A Kundaje
Advances in Neural Information Processing Systems 29, 2016
72016
Network modelling of topological domains using Hi-C data
YXR Wang, P Sarkar, O Ursu, A Kundaje, PJ Bickel
The annals of applied statistics 13 (3), 1511, 2019
62019
Network modeling of kinase inhibitor polypharmacology reveals pathways targeted in chemical screens
O Ursu, SJC Gosline, N Beeharry, L Fink, V Bhattacharjee, SC Huang, ...
Plos one 12 (10), e0185650, 2017
42017
Methods and compositions for massively parallel variant and small molecule phenotyping
A Regev, P Thakore, J Doench, JT Neal, J Boehm, O Ursu
US Patent App. 16/809,458, 2020
22020
Massively parallel phenotyping of coding variants in cancer with Perturb-seq (vol 40, pg 896, 2022)
O Ursu, JT Neal, E Shea, PI Thakore, L Jerby-Arnon, L Nguyen, D Dionne, ...
NATURE BIOTECHNOLOGY 40 (11), 1691-1691, 2022
2022
Understanding Gene Regulation and Genetic Variation Through the Lens of Three-Dimensional Genome Architecture
O Ursu
Stanford University, 2018
2018
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Articles 1–15