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Helmuth Gehart
Helmuth Gehart
Institute for Molecular Health Sciences, ETH Zurich
Verified email at biol.ethz.ch
Title
Cited by
Cited by
Year
Long-term culture of genome-stable bipotent stem cells from adult human liver
M Huch, H Gehart, R Van Boxtel, K Hamer, F Blokzijl, MMA Verstegen, ...
Cell 160 (1), 299-312, 2015
14412015
Tales from the crypt: new insights into intestinal stem cells
H Gehart, H Clevers
Nature reviews Gastroenterology & hepatology 16 (1), 19-34, 2019
7622019
Long-term expansion of functional mouse and human hepatocytes as 3D organoids
H Hu, H Gehart, B Artegiani, C LÖpez-Iglesias, F Dekkers, O Basak, ...
Cell 175 (6), 1591-1606. e19, 2018
5932018
MAPK signalling in cellular metabolism: stress or wellness?
H Gehart, S Kumpf, A Ittner, R Ricci
EMBO reports 11 (11), 834-840, 2010
3242010
Identification of enteroendocrine regulators by real-time single-cell differentiation mapping
H Gehart, JH van Es, K Hamer, J Beumer, K Kretzschmar, JF Dekkers, ...
Cell 176 (5), 1158-1173. e16, 2019
2542019
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids
A Marsee, FJM Roos, MMA Verstegen, F Roos, M Verstegen, H Clevers, ...
Cell Stem Cell 28 (5), 816-832, 2021
1642021
Chuva de Sousa Lopes, SM; Begthel, H.; Korving, J.; et al. Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
H Hu, H Gehart, B Artegiani, C LÖpez-Iglesias, F Dekkers, O Basak, ...
Cell 175 (6), 1591-1606, 2018
1492018
Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1
MA Kerenyi, F Grebien, H Gehart, M Schifrer, M Artaker, B Kovacic, ...
Blood, The Journal of the American Society of Hematology 112 (9), 3878-3888, 2008
1312008
Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung
A Ittner, H Block, CA Reichel, M Varjosalo, H Gehart, G Sumara, ...
Journal of Experimental Medicine 209 (12), 2229-2246, 2012
1002012
The BAR domain protein Arfaptin-1 controls secretory granule biogenesis at the trans-Golgi network
H Gehart, A Goginashvili, R Beck, J Morvan, E Erbs, I Formentini, ...
Developmental cell 23 (4), 756-768, 2012
932012
Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma
E De Crignis, T Hossain, S Romal, F Carofiglio, P Moulos, MM Khalid, ...
Elife 10, e60747, 2021
822021
Exploring the human lacrimal gland using organoids and single-cell sequencing
M Bannier-Hélaouët, Y Post, J Korving, MT Bustos, H Gehart, H Begthel, ...
Cell stem cell 28 (7), 1221-1232. e7, 2021
682021
NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor
L Novellasdemunt, A Kucharska, C Jamieson, M Prange‐Barczynska, ...
The EMBO journal 39 (3), e102771, 2020
652020
Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure
EW Kuijk, S Rasmussen, F Blokzijl, M Huch, H Gehart, P Toonen, ...
Scientific reports 6 (1), 22154, 2016
612016
Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease
MMA Verstegen, FJM Roos, K Burka, H Gehart, M Jager, M de Wolf, ...
Scientific reports 10 (1), 21900, 2020
502020
Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a COMMD1-Deficient Dog Model of Metabolic Liver Disease
HS Kruitwagen, LA Oosterhoff, ME van Wolferen, C Chen, ...
Cells 9 (2), 410, 2020
502020
Enteroendocrine dynamics–new tools reveal hormonal plasticity in the gut
J Beumer, H Gehart, H Clevers
Endocrine reviews 41 (5), bnaa018, 2020
452020
The intestinal epithelium–fluid fate and rigid structure from crypt bottom to villus tip
V Bonis, C Rossell, H Gehart
Frontiers in cell and developmental biology 9, 661931, 2021
432021
A human organoid model of aggressive hepatoblastoma for disease modeling and drug testing
JA Saltsman, WJ Hammond, NJC Narayan, D Requena, H Gehart, ...
Cancers 12 (9), 2668, 2020
432020
Repairing organs: lessons from intestine and liver
H Gehart, H Clevers
Trends in Genetics 31 (6), 344-351, 2015
302015
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