Hartmut Jaeschke
Hartmut Jaeschke
University Distinguished Professor and Chair, University of Kansas Medical Center
Verified email at kumc.edu
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
autophagy 12 (1), 1-222, 2016
75462016
Mechanisms of hepatotoxicity
H Jaeschke, GJ Gores, AI Cederbaum, JA Hinson, D Pessayre, ...
Toxicological sciences 65 (2), 166-176, 2002
15462002
Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning
H Jaeschke
American Journal of Physiology-Gastrointestinal and Liver Physiology 284 (1 …, 2003
10712003
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating …
P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ...
Archives of toxicology 87 (8), 1315-1530, 2013
10072013
Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver
H Jaeschke, A Farhood
American Journal of Physiology-Gastrointestinal and Liver Physiology 260 (3 …, 1991
9471991
Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo
H Jaeschke, A Farhood, CW Smith
The FASEB Journal 4 (15), 3355-3359, 1990
8991990
Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity
H Jaeschke, MR McGill, A Ramachandran
Drug metabolism reviews 44 (1), 88-106, 2012
6962012
Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury
H Jaeschke, JJ Lemasters
Gastroenterology 125 (4), 1246-1257, 2003
6402003
The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation
MR McGill, MR Sharpe, CD Williams, M Taha, SC Curry, H Jaeschke
The Journal of clinical investigation 122 (4), 1574-1583, 2012
6112012
Intracellular signaling mechanisms of acetaminophen-induced liver cell death
H Jaeschke, ML Bajt
Toxicological sciences 89 (1), 31-41, 2006
5732006
Mechanisms of neutrophil‐induced parenchymal cell injury
H Jaeschke, CW Smith
Journal of leukocyte biology 61 (6), 647-653, 1997
5501997
Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts
H Jaeschke
Journal of gastroenterology and hepatology 26, 173-179, 2011
5192011
Mechanisms of Liver Injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions
H Jaeschke
American Journal of Physiology-Gastrointestinal and Liver Physiology 290 (6 …, 2006
5122006
The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity
H Jaeschke, TR Knight, ML Bajt
Toxicology letters 144 (3), 279-288, 2003
4822003
Mitochondrial permeability transition in acetaminophen‐induced necrosis and apoptosis of cultured mouse hepatocytes
K Kon, JS Kim, H Jaeschke, JJ Lemasters
Hepatology 40 (5), 1170-1179, 2004
4662004
Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis?
JS Gujral, TR Knight, A Farhood, ML Bajt, H Jaeschke
Toxicological sciences 67 (2), 322-328, 2002
4332002
Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis?
JS Gujral, TJ Bucci, A Farhood, H Jaeschke
Hepatology 33 (2), 397-405, 2001
4332001
Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis
MR McGill, H Jaeschke
Pharmaceutical research 30 (9), 2174-2187, 2013
4272013
Reactive oxygen and mechanisms of inflammatory liver injury
H Jaeschke
Journal of gastroenterology and hepatology 15 (7), 718-724, 2000
3982000
Activation of caspase 3 (CPP32)-like proteases is essential for TNF-α-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model
H Jaeschke, MA Fisher, JA Lawson, CA Simmons, A Farhood, DA Jones
The Journal of Immunology 160 (7), 3480-3486, 1998
3961998
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